Protein Alignment JMJD7 and JMJD7-PLA2G4B

DIOPT Version :10

• Sequence 1: NP_648651.1
• Gene: JMJD7 / 39514
• FlyBaseID: FBgn0036366
• Length: 316
• Species: Drosophila melanogaster
• Sequence 2: NP_005081.1
• Gene: JMJD7-PLA2G4B / 8681
• HGNCID: 34449
• Length: 1012
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 104/272 - (38%)
• Similarity: 147/272 - (54%)
• Gaps: 39/272 - (14%)

  Fly     5 ERALDVLLQE-------AEELCIGSSVVELDRIPTALEFCREFYSKNQPVVIRKAL-NWPAIGKW 61
            |.||:.:..|       |.|||:..:|..||:.||.|.|.|::...|:|.:||.|| :|||:.||
Human     3 EAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKW 67

  Fly    62 TPKYLIEALGDRSVDVAITPNGYADGLATQNGQEYFVLPLETKMKLSEVV----RRLDDPTGAVH 122
            :..|....:|...|.||:||:||||.:.    .:.|::|.|.::.||.|:    .|...|  .|.
Human    68 SLPYFRATVGSTEVSVAVTPDGYADAVR----GDRFMMPAERRLPLSFVLDVLEGRAQHP--GVL 126

  Fly   123 YIQKQNSNLSVDLPELAADLRVSDLDFAQQSFNKPPDAVNFWLGDERAVTSMHKDPYENVYCVIS 187
            |:|||.|||..:||:|..||. |.:.:|.::..|.|||||||||:..||||:|||.|||:|||:|
Human   127 YVQKQCSNLPSELPQLLPDLE-SHVPWASEALGKMPDAVNFWLGEAAAVTSLHKDHYENLYCVVS 190

  Fly   188 GHKDFVLIPPHQLSCVPRGIYPTGVYKTSDSGQFYIEPLRDEEGSDQFTEWVSVDPLSPDLAKYP 252
            |.|.|:..||.....:|..:|....|:.::.|.|.:.   |||..::                 .
Human   191 GEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVV---DEEAMEK-----------------A 235

  Fly   253 EYARAKPLKVRV 264
            |.:|...|.|||
Human   236 EVSRTCLLTVRV 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JMJD7	NP_648651.1	Cupin_8	33..299	CDD:463936	91/237 (38%)
JMJD7-PLA2G4B	NP_005081.1	Cupin_8	38..>223	CDD:463936	80/191 (42%)
		C2_cPLA2	242..361	CDD:176001	4/6 (67%)
		cPLA2_C2	382..473	CDD:465834
		cPLA2_Grp-IVB-IVD-IVE-IVF	474..999	CDD:132840