DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JMJD7 and Kdm8

DIOPT Version :9

Sequence 1:	NP_648651.1	Gene:	JMJD7 / 39514	FlyBaseID:	FBgn0036366	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_084118.1	Gene:	Kdm8 / 77035	MGIID:	1924285	Length:	414	Species:	Mus musculus

Alignment Length:	293	Identity:	70/293 - (23%)
Similarity:	123/293 - (41%)	Gaps:	58/293 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ALDVLLQEAEELCIGSSVVELDRIPTALEFCREFYSKNQPVVIR-KALNWPAIGKWTPKYLIEAL 70
            |.||:|:.         :|...|.|....|.:.|....:||::. .|.:||.:.||:.:|:.|..
Mouse   173 APDVMLER---------MVPRLRCPPLQYFKQHFLVPGRPVILEGVADHWPCMKKWSLQYIQEIA 228

  Fly    71 GDRSVDVAITPNGYADGLATQNGQEYFVLPLETKMKLSEVVRR--LDDPTGAVHYIQKQNSNLSV 133
            |.|:|.|.: .:.|.|...:|           |.|.:.|.:::  |.:.....:..|.|   |..
Mouse   229 GCRTVPVEV-GSRYTDEDWSQ-----------TLMTVDEFIQKFILSEAKDVGYLAQHQ---LFD 278

  Fly   134 DLPELAADLRVSD---LDFAQQSFNKPPDAVNFWLGDERAVTSMHKDPYENVYCVISGHKDFVLI 195
            .:|||..|:.:.|   |...::.    ...:|.|.|.:..::.:|:||.:|....:.|.|...|.
Mouse   279 QIPELKRDISIPDYCCLGNGEEE----EITINAWFGPQGTISPLHQDPQQNFLVQVLGRKYIRLY 339

  Fly   196 PPHQLSCVPRGIYPTGVYKTSDSGQFYIEPLRDEEGSDQFTEWVSVDPLSPDLAKYPEYARAKPL 260
            .|.:    ...:||...:...::.|                    ||..:|||.|:|::..|..|
Mouse   340 SPQE----SEAVYPHETHILHNTSQ--------------------VDVENPDLEKFPKFTEAPFL 380

  Fly   261 KVRVHAGDILYLPNYWFHHVSQSHKCIAVNFWY 293
            ...:..||.|::|..::|:|.......:|:||:
Mouse   381 SCILSPGDTLFIPAKYWHYVRSLDLSFSVSFWW 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JMJD7	NP_648651.1	Cupin_8	33..298	CDD:290351	63/267 (24%)
Kdm8	NP_084118.1	Interaction with RCCD1. /evidence=ECO:0000250\|UniProtKB:Q8N371	1..107
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	148..169
		Cupin_8	189..414	CDD:290351	63/268 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385616at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920