DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JMJD7 and jmjd7

DIOPT Version :9

Sequence 1:	NP_648651.1	Gene:	JMJD7 / 39514	FlyBaseID:	FBgn0036366	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_001017615.1	Gene:	jmjd7 / 550278	ZFINID:	ZDB-GENE-050417-86	Length:	311	Species:	Danio rerio

Alignment Length:	316	Identity:	145/316 - (45%)
Similarity:	204/316 - (64%)	Gaps:	12/316 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEVERALDVLLQEAEELCIGSSVVELDRIPTALEFCREFYSKNQPVVIRKALN-WPAIGKWTPK 64
            |.||:..|....:||.||.:..:|..||...:.|:|.|::...|:|.:||.|.| |||:.||.|.
Zfish     1 MDEVKECLRDFPKEARELYLNDAVPYLDEPLSPLQFYRDWIGPNKPCIIRNAFNDWPALSKWNPT 65

  Fly    65 YLIEALGDRSVDVAITPNGYADGLATQNGQEYFVLPLETKMKLSEVVRRLDD--PTGAVHYIQKQ 127
            ||.|.:|.:.:.||:||||:||.:   ||.. ||:|.|.:|..|.::..::.  .:.||.|:|||
Zfish    66 YLREKVGSKVISVAVTPNGFADAV---NGNR-FVMPEERQMSFSSLLDIVEGKIKSSAVFYVQKQ 126

  Fly   128 NSNLSVDLPELAADLRVSDLDFAQQSFNKPPDAVNFWLGDERAVTSMHKDPYENVYCVISGHKDF 192
            .|||..::|||..|:: :.:.:..::..|.|||||||||:|.||||||||.|||:||||||.|:|
Zfish   127 CSNLMEEIPELTGDVQ-THIPWMSEALGKLPDAVNFWLGEESAVTSMHKDHYENLYCVISGQKEF 190

  Fly   193 VLIPPHQLSCVPRGIYPTGVYKTSDSGQFYIEPLRDEEGSDQFTEWVSVDPLSPDLAKYPEYARA 257
            :|:||.....:|..:|....|:..|.|.|.|.   |||.|.: ..|:.:|||.||..::|.|..|
Zfish   191 ILLPPTDRPFIPYELYQPATYRQKDDGTFEIV---DEENSPK-VPWIPLDPLKPDFERFPSYRHA 251

  Fly   258 KPLKVRVHAGDILYLPNYWFHHVSQSHKCIAVNFWYDLDYDSRYCYYRMLEQMTSA 313
            |.|...|.||::||||:.|||||.|||.|||||||||::||.:|.|::::|.:|:|
Zfish   252 KALHCTVKAGEMLYLPSLWFHHVRQSHGCIAVNFWYDMEYDIKYNYFQLVEALTNA 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JMJD7	NP_648651.1	Cupin_8	33..298	CDD:290351	127/267 (48%)
jmjd7	NP_001017615.1	Cupin_8	33..293	CDD:290351	128/268 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590401
Domainoid	1	1.000	260	1.000	Domainoid score	I1940
eggNOG	1	0.900	-	-		E1_COG1226
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H98398
Inparanoid	1	1.050	288	1.000	Inparanoid score	I2813
OMA	1	1.010	-	-		QHG55344
OrthoDB	1	1.010	-	-		D1385616at2759
OrthoFinder	1	1.000	-	-		FOG0005404
OrthoInspector	1	1.000	-	-		oto40452
orthoMCL	1	0.900	-	-		OOG6_104630
Panther	1	1.100	-	-	LDO	PTHR12461
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5663
SonicParanoid	1	1.000	-	-		X4973
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800