DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JMJD7 and Jmjd7

DIOPT Version :9

Sequence 1:	NP_648651.1	Gene:	JMJD7 / 39514	FlyBaseID:	FBgn0036366	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_001108109.1	Gene:	Jmjd7 / 433466	MGIID:	3845785	Length:	316	Species:	Mus musculus

Alignment Length:	318	Identity:	140/318 - (44%)
Similarity:	199/318 - (62%)	Gaps:	16/318 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEVERALDVLLQEAEELCIGSSVVELDRIPTALEFCREFYSKNQPVVIRKAL-NWPAIGKWTPK 64
            :..|.|||......|.:|.:...|..||..|:.|.|.|::...|:|.:||.|| :|||:.||:..
Mouse     6 LEAVRRALQEFPAAARDLNVPRVVPYLDEPPSPLCFYRDWVCPNRPCIIRNALQHWPALQKWSLS 70

  Fly    65 YLIEALGDRSVDVAITPNGYADGLATQNGQEYFVLPLETKMKLSEVV----RRLDDPTGAVHYIQ 125
            ||...:|...|.||:||:||||.:.    .:.||:|.|.::.:|.|:    .|...|  .|.|:|
Mouse    71 YLRATVGSTEVSVAVTPDGYADAVR----GDRFVMPAERRLPISHVLDVLEGRAQHP--GVLYVQ 129

  Fly   126 KQNSNLSVDLPELAADLRVSDLDFAQQSFNKPPDAVNFWLGDERAVTSMHKDPYENVYCVISGHK 190
            ||.|||..:||:|.:|:. |.:.:|.:|..|.||||||||||..||||:|||.|||:|||:||.|
Mouse   130 KQCSNLPTELPQLLSDIE-SHVPWASESLGKMPDAVNFWLGDASAVTSLHKDHYENLYCVVSGEK 193

  Fly   191 DFVLIPPHQLSCVPRGIYPTGVYKTSDSGQFYIEPLRDEEGSDQFTEWVSVDPLSPDLAKYPEYA 255
            .|:|.||.....:|..:|....|:.::.|.|.:.   |||..:: ..|:.:|||:|||.:||.|:
Mouse   194 HFLLHPPSDRPFIPYNLYTPATYQLTEEGTFRVV---DEEAMEK-VPWIPLDPLAPDLTQYPSYS 254

  Fly   256 RAKPLKVRVHAGDILYLPNYWFHHVSQSHKCIAVNFWYDLDYDSRYCYYRMLEQMTSA 313
            :|:.|...|.||::||||..|||||.|||.|||||||||::||.:|.|:::::.:|.|
Mouse   255 QAQALHCTVRAGEMLYLPALWFHHVQQSHGCIAVNFWYDMEYDLKYSYFQLMDTLTRA 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JMJD7	NP_648651.1	Cupin_8	33..298	CDD:290351	124/269 (46%)
Jmjd7	NP_001108109.1	Cupin_8	38..297	CDD:290351	124/269 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845757
Domainoid	1	1.000	248	1.000	Domainoid score	I2138
eggNOG	1	0.900	-	-		E1_COG1226
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H98398
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2980
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55344
OrthoDB	1	1.010	-	-		D1385616at2759
OrthoFinder	1	1.000	-	-		FOG0005404
OrthoInspector	1	1.000	-	-		oto92253
orthoMCL	1	0.900	-	-		OOG6_104630
Panther	1	1.100	-	-	LDO	PTHR12461
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5663
SonicParanoid	1	1.000	-	-		X4973
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840