DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10140 and CG4835

DIOPT Version :9

Sequence 1:	NP_648648.2	Gene:	CG10140 / 39511	FlyBaseID:	FBgn0036363	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_647965.3	Gene:	CG4835 / 38619	FlyBaseID:	FBgn0035607	Length:	1224	Species:	Drosophila melanogaster

Alignment Length:	362	Identity:	79/362 - (21%)
Similarity:	119/362 - (32%)	Gaps:	106/362 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PKDLDVSGTT-----DSTLETDSTTSGLEYGLITGNLSICGNVADNVFLPFVGDCNRYYLCRSGQ 80
            |..|...|:|     .:|.|..:||.||...:...:   |.:..|.....::|:|:.|.:|:..|
  Fly   357 PTTLPSDGSTTEIHSSTTEEIVTTTDGLPSDVDPND---CKDEKDGTIFAYIGNCSEYLICKDNQ 418

  Fly    81 AIELQCEWPYEFNANTQSCVHPGDADCL---------------------PTCEAFNFST------ 118
            .....|.....||.:...|..|.|..||                     ||......:|
  Fly   419 VQMGHCPPNTLFNPDLLVCDEPDDVVCLGDRTTTPIPTTIPTTTTEKTTPTTTTTTVATTLGPDQ 483

  Fly   119 ----------FSYQRTCTRYVLCY-YGKPVLRQCQDGLQYNSATDRCD--------FPQNVDCVE 164
                      |||...|::|.||. .|:..|..|..|..::.:|.:|.        .|..|....
  Fly   484 LCDGQELGASFSYPDDCSKYYLCLGGGQWTLAPCIYGSYFDPSTGQCGPDVAPDACKPSQVTTTT 548

  Fly   165 SECSIYSNAYHLRYVPSKV-------------------------------SCQKYFICGNGIPRE 198
            :..:..:........|...                               :|.||.:|.:.||..
  Fly   549 TTTTTETTTTERNTTPKSTATTTERTTTTVAPKTGICGGRNENENIAYPNNCTKYIVCVSPIPIA 613

  Fly   199 QTCTAGLHFSTKCD-CCDIPSKSDCQIPAVERKVQQLSRLSPVTTVGICPPSGVHFYVHESRRDA 262
            ..|..|..||:|.: |.|...:|||:      ..|..:.|.|    |...|.........|.||.
  Fly   614 FFCPDGTFFSSKLEKCIDDWDESDCE------GDQSTTTLEP----GYTRPPPEPTMCTNSSRDT 668

  Fly   263 YYY---------CVDGHGLVLD-CSAGLWYDPTVQEC 289
            :.|         |||.:..::| |:.|.:|||..::|
  Fly   669 FPYPDNCQWFIRCVDDYIYMMDVCNCGEYYDPITEKC 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10140	NP_648648.2	CBM_14	63..106	CDD:279884	11/42 (26%)
		CBM_14	111..161	CDD:279884	15/74 (20%)
		CBM_14	178..222	CDD:279884	15/75 (20%)
		CBM_14	246..295	CDD:279884	15/54 (28%)
CG4835	NP_647965.3	CBM_14	51..103	CDD:279884
		CBM_14	185..237	CDD:279884
		CBM_14	273..322	CDD:279884
		CBM_14	393..444	CDD:279884	13/50 (26%)
		CBM_14	485..539	CDD:279884	13/53 (25%)
		CBM_14	585..638	CDD:279884	14/52 (27%)
		CBM_14	661..714	CDD:279884	14/45 (31%)
		CBM_14	744..796	CDD:279884
		CBM_14	914..962	CDD:279884
		CBM_14	1175..1212	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444067
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D33909at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950