DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10154 and CG4835

DIOPT Version :9

Sequence 1:	NP_001189089.1	Gene:	CG10154 / 39509	FlyBaseID:	FBgn0036361	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_647965.3	Gene:	CG4835 / 38619	FlyBaseID:	FBgn0035607	Length:	1224	Species:	Drosophila melanogaster

Alignment Length:	390	Identity:	89/390 - (22%)
Similarity:	130/390 - (33%)	Gaps:	151/390 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VHRNRADEDLVVAPG-PDDDGEGLNVQDKDIYDMYENTQINVCGNVADGVYLPYVGNCSKYIECE 80
            :|.:..:|.:....| |.|                  ...|.|.:..||....|:||||:|:.|:
  Fly   369 IHSSTTEEIVTTTDGLPSD------------------VDPNDCKDEKDGTIFAYIGNCSEYLICK 415

  Fly    81 NNTIKEVGSCLDLAKDNPDICDPNKSCELGYDPVLQVCTYMEEVQCL------------------ 127
            :|.: ::|.           |.||..    ::|.|.||...::|.||
  Fly   416 DNQV-QMGH-----------CPPNTL----FNPDLLVCDEPDDVVCLGDRTTTPIPTTIPTTTTE 464

  Fly   128 ---PT---------------CESFRL-SSFCYDNTCTKYVLCY-YGKPVLRQCHDGLQYNNATDR 172
               ||               |:...| :||.|.:.|:||.||. .|:..|..|..|..::.:|.:
  Fly   465 KTTPTTTTTTVATTLGPDQLCDGQELGASFSYPDDCSKYYLCLGGGQWTLAPCIYGSYFDPSTGQ 529

  Fly   173 CDFPEYVDCVAND-----------------------------------------------CSATF 190
            |. |:    ||.|                                               |....
  Fly   530 CG-PD----VAPDACKPSQVTTTTTTTTTETTTTERNTTPKSTATTTERTTTTVAPKTGICGGRN 589

  Fly   191 QPEDIIYLGSKASCSKYYVCSNGHPWEQQCAPGLAYNPSC-KCCDFAKNVNCTIDAVARNILP-Y 253
            :.|:|.|   ..:|:||.||.:..|....|..|..::... ||.|.....:|..|.....:.| |
  Fly   590 ENENIAY---PNNCTKYIVCVSPIPIAFFCPDGTFFSSKLEKCIDDWDESDCEGDQSTTTLEPGY 651

  Fly   254 SRTPLRRADIKCPLMGTHFFPHKSRRDAYYY---------CVEGRGVTLD-CTPGLYYDPKVEDC 308
            :|.|..      |.|.|:     |.||.:.|         ||:.....:| |..|.||||..|.|
  Fly   652 TRPPPE------PTMCTN-----SSRDTFPYPDNCQWFIRCVDDYIYMMDVCNCGEYYDPITEKC 705

Fly 309 308
Fly 706 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10154	NP_001189089.1	CBM_14	130..180	CDD:279884	17/51 (33%)
		CBM_14	197..239	CDD:279884	12/42 (29%)
		ChtBD2	263..311	CDD:214696	18/56 (32%)
CG4835	NP_647965.3	CBM_14	51..103	CDD:279884
		CBM_14	185..237	CDD:279884
		CBM_14	273..322	CDD:279884
		CBM_14	393..444	CDD:279884	19/66 (29%)
		CBM_14	485..539	CDD:279884	20/58 (34%)
		CBM_14	585..638	CDD:279884	15/55 (27%)
		CBM_14	661..714	CDD:279884	16/50 (32%)
		CBM_14	744..796	CDD:279884
		CBM_14	914..962	CDD:279884
		CBM_14	1175..1212	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444066
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D33909at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950