DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10154 and C39D10.7

DIOPT Version :9

Sequence 1:	NP_001189089.1	Gene:	CG10154 / 39509	FlyBaseID:	FBgn0036361	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_509334.3	Gene:	C39D10.7 / 181050	WormBaseID:	WBGene00016534	Length:	1171	Species:	Caenorhabditis elegans

Alignment Length:	382	Identity:	84/382 - (21%)
Similarity:	126/382 - (32%)	Gaps:	125/382 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 DGEGLNVQDKDIYDMYENTQINVCGNVADGVYLPYVGNCSKYIECENNTIKEVGSCLDL-AKDNP 98
            ||...:...|.::.:..|.|:......|:.::.||||      ||:.:|  .|..|... ....|
Worm   565 DGNHASGLCKSVFYICANGQVVATTCPANLIFNPYVG------ECDYST--NVRDCQGYQPTTTP 621

  Fly    99 DICDP--------NKSCELGYDPVLQVCTYMEEVQCLP------------TCESFRLSSFC---- 139
            ....|        ..|...||.|:       |.....|            |..|.:.::.|
Worm   622 SYSYPKTTSKPYEQPSTTQGYAPI-------EYTPVTPGYAPQYTSTIFTTTLSPKYAAMCAKRD 679

  Fly   140 ---YDNTCTKYVL-CYYGKPVLRQCHDGLQYNNATDRCDFPEYVD-C----VANDCSATFQPEDI 195
               |...|.||:: ||..|.....|..||.|:...|:||..|.|: |    ...|.:...:...|
Worm   680 DGNYGFDCEKYLIKCYNRKTFKFPCPSGLYYSRLQDKCDVKENVEGCPEYKPTTDATPAAEQPVI 744

  Fly   196 IYLG-------SKA--------------------------SCSKYYV-CSNGHPWEQQCAPGLAY 226
            .|..       :||                          .|..||: |:|......:|..||.|
Worm   745 SYQNYGYSQSTTKAYNPSVTTPSPQHAAFCERLENGNYGLDCEDYYISCNNFETTINRCPAGLFY 809

  Fly   227 NPSCKCCDFAKNV-NC---------------------------TIDAVARNILPYSRTPLRRADI 263
            :.....||:.::| :|                           .||..:....|...|||.:| .
Worm   810 SKLNNRCDYKEHVEDCPEYKPTPSTTPAAEQPGTTKYTTYNYPNIDYTSTTPGPVDTTPLAKA-F 873

  Fly   264 KCPLM--GTHFFPHKSRRDAYYYCVEGRGVTLDCTPGLYYDPK---------VEDCR 309
            .|...  |.:..|:.|:  .|..|::||.:...|.|||:|:.|         |:.|:
Worm   874 SCSGRPDGIYALPYCSQ--DYVQCMQGRSLISSCAPGLFYNEKNGMCAYKHTVDTCK 928

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10154	NP_001189089.1	CBM_14	130..180	CDD:279884	17/57 (30%)
		CBM_14	197..239	CDD:279884	14/75 (19%)
		ChtBD2	263..311	CDD:214696	16/58 (28%)
C39D10.7	NP_509334.3	CBM_14	29..79	CDD:279884
		CBM_14	98..148	CDD:279884
		CBM_14	189..242	CDD:279884
		ChtBD2	337..384	CDD:214696
		CBM_14	419..467	CDD:279884
		CBM_14	560..612	CDD:279884	14/54 (26%)
		CBM_14	675..726	CDD:279884	17/50 (34%)
		CBM_14	774..825	CDD:279884	12/50 (24%)
		CBM_14	875..927	CDD:279884	15/53 (28%)
		CBM_14	941..992	CDD:279884
		CBM_14	1010..1062	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920