DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10222 and GPN2

DIOPT Version :9

Sequence 1:	NP_001287060.1	Gene:	CG10222 / 39504	FlyBaseID:	FBgn0036356	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_014905.1	Gene:	GPN2 / 854436	SGDID:	S000005788	Length:	347	Species:	Saccharomyces cerevisiae

Alignment Length:	302	Identity:	125/302 - (41%)
Similarity:	189/302 - (62%)	Gaps:	28/302 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 YGQLIIGPPGSGKTTYCGEALKFYRELGRQVGVVNLDPANENMSYEPVLSVMELITVEDCMEHLK 80
            :.|::||||||||:|||....:|:..:||...|||:||||:.:.|...:.:.:.||:|:.|:..:
Yeast     3 FAQIVIGPPGSGKSTYCNGCSQFFNAIGRHSQVVNMDPANDALPYPCAVDIRDFITLEEIMQEQQ 67

  Fly    81 LGPNGALMHCAEYLADHLEDWLLPALRKLSATYNYFLFDCPGQVELYTHHNAMARIFERLERE-- 143
            |||||.||:..|.|.:.::.::|.....:.....|.:|||||||||:|||:::..||:::|:|
Yeast    68 LGPNGGLMYAVESLDNSIDLFILQIKSLVEEEKAYLVFDCPGQVELFTHHSSLFNIFKKMEKELD 132

  Fly   144 -RYSLVTVNLIDSHYCSEPAKFIATLLMALNTMLRMSLPHVNVLSKADLLKKHETKLHFNVDYYT 207
             |:.:  |||||..|.:.|:::|:.||:||.:||.|.|||:||.||.|:||.: .:|.|.:||||
Yeast   133 IRFCV--VNLIDCFYMTSPSQYISILLLALRSMLMMDLPHINVFSKIDMLKSY-GELPFRLDYYT 194

  Fly   208 DVLDLKYL---LDKLDDDPAMRKYRKLNAAICSMVEDYALVSFQLLDVFSTDSMLRLRNHIDKAN 269
            :|.||.||   ::|.......:||.||...|..:|.|:.||||::|.|...:||:.|:..|||||
Yeast   195 EVQDLDYLEPYIEKEGSSVLGKKYSKLTETIKELVSDFNLVSFEVLSVDDKESMINLQGVIDKAN 259

  Fly   270 GYVYKAGEEQTVNSLLACAVGAET---EAAR-----MEHDVQ 303
            ||::.|.|           ||.:|   ||:|     ..:|:|
Yeast   260 GYIFGASE-----------VGGDTVWAEASREGALIANYDIQ 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10222	NP_001287060.1	Gem1	19..193	CDD:224025	77/176 (44%)
CG10222	NP_001287060.1	ATP_bind_1	20..271	CDD:281079	112/256 (44%)
GPN2	NP_014905.1	GPN2	3..257	CDD:349780	109/256 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346747
Domainoid	1	1.000	221	1.000	Domainoid score	I451
eggNOG	1	0.900	-	-		E2759_KOG1533
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7006
Inparanoid	1	1.050	233	1.000	Inparanoid score	I718
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54489
OrthoFinder	1	1.000	-	-		FOG0005210
OrthoInspector	1	1.000	-	-		oto98980
orthoMCL	1	0.900	-	-		OOG6_102415
Panther	1	1.100	-	-	LDO	PTHR21231
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R520
SonicParanoid	1	1.000	-	-		X3724
TreeFam	1	0.960	-	-
	15	14.790