DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10222 and gpn2

DIOPT Version :9

Sequence 1:	NP_001287060.1	Gene:	CG10222 / 39504	FlyBaseID:	FBgn0036356	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_012812548.1	Gene:	gpn2 / 595033	XenbaseID:	XB-GENE-5751862	Length:	318	Species:	Xenopus tropicalis

Alignment Length:	280	Identity:	128/280 - (45%)
Similarity:	195/280 - (69%)	Gaps:	12/280 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 YGQLIIGPPGSGKTTYCGEALKFYRELGRQVGVVNLDPANENMSYEP--VLSVMELITVEDCMEH 78
            :||.:||||||||:||.........::||:..::|||||.|:   ||  .:|:.||:.:|:.|..
Frog    20 FGQAVIGPPGSGKSTYVRAMQALLAQMGRKSAIINLDPAGED---EPGAAVSLRELLGLEEVMSE 81

  Fly    79 LKLGPNGALMHCAEYLADHLEDWLLPALRKLSATYNYFLFDCPGQVELYTHHNAMARIFERLERE 143
            |:|||||||::|.|||.::| |||...|:.|..|  |||.||||||||||||.|:..:..||...
Frog    82 LRLGPNGALLYCMEYLQENL-DWLRGRLQGLRGT--YFLLDCPGQVELYTHHPALPDVLRRLGAW 143

  Fly   144 RYSLVTVNLIDSHYCSEPAKFIATLLMALNTMLRMSLPHVNVLSKADLLKKHETKLHFNVDYYTD 208
            ...|..|:|:|||||::|||||:.|..:|:|||.:.|||:|||||.||:::: .:|.||:||||:
Frog   144 GLRLCAVHLVDSHYCTDPAKFISVLCTSLSTMLHVELPHINVLSKMDLIEQY-GRLAFNLDYYTE 207

  Fly   209 VLDLKYLLDKLDDDPAMRKYRKLNAAICSMVEDYALVSFQLLDVFSTDSMLRLRNHIDKANGYVY 273
            |:||.||:::|..||..|::::|:..:..:::||.||:|..|.:....|:..:.:.:|||:|:.:
Frog   208 VMDLSYLVEQLTSDPFFRRHKRLHEKLAEVIQDYGLVTFMPLSIKDEKSLRLVLSAVDKASGFCF 272

  Fly   274 KAGE-EQTVNSLLACAVGAE 292
              || :|::.:|::.||||:
Frog   273 --GETKQSLGNLMSVAVGAD 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10222	NP_001287060.1	Gem1	19..193	CDD:224025	90/175 (51%)
CG10222	NP_001287060.1	ATP_bind_1	20..271	CDD:281079	117/252 (46%)
gpn2	XP_012812548.1	GPN2	20..266	CDD:349780	116/252 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	234	1.000	Domainoid score	I2337
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7006
Inparanoid	1	1.050	251	1.000	Inparanoid score	I3148
OMA	1	1.010	-	-		QHG54489
OrthoDB	1	1.010	-	-		D432496at33208
OrthoFinder	1	1.000	-	-		FOG0005210
OrthoInspector	1	1.000	-	-		oto102296
Panther	1	1.100	-	-	LDO	PTHR21231
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R520
SonicParanoid	1	1.000	-	-		X3724
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110