DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10222 and Gpn3

DIOPT Version :9

Sequence 1:	NP_001287060.1	Gene:	CG10222 / 39504	FlyBaseID:	FBgn0036356	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_973720.2	Gene:	Gpn3 / 360810	RGDID:	1303034	Length:	284	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	109/267 - (40%)
Similarity:	160/267 - (59%)	Gaps:	13/267 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 PRYGQLIIGPPGSGKTTYCGEALKFYRELGRQVGVVNLDPANENMSYEPVLSVMELITVEDCME- 77
            |||.||::||.||||:|||...::....|.|.|.|||||||.|:.:|..:..:.|||.|:|.||
  Rat     2 PRYAQLVMGPAGSGKSTYCSTMVQHCEALNRSVQVVNLDPAAEHFNYPVMADIRELIEVDDVMED 66

  Fly    78 -HLKLGPNGALMHCAEYLADHLEDWLLPALRKLSATYNYFLFDCPGQVELYTHHNAMARIFERLE 141
             .|:.||||.|:.|.||.|::. |||...|..:..  :|.|||||||:|||||...|.::.::||
  Rat    67 DSLRFGPNGGLVFCMEYFANNF-DWLENCLGHVED--DYILFDCPGQIELYTHLPVMKQLVQQLE 128

  Fly   142 RERYSLVTVNLIDSHYCSEPAKFIATLLMALNTMLRMSLPHVNVLSKADLLKKHETKLHFNVDYY 206
            :..:.:..|.|:||.:..|..|||:.:|.||:.|:.:.:|.||:::|.|||.|...|   .::.:
  Rat   129 QWEFRVCGVFLVDSQFMVESFKFISGILAALSAMISLEIPQVNIMTKMDLLSKKAKK---EIEKF 190

  Fly   207 TDVLDLKYLLDKLDDDPAMRKYRKLNAAICSMVEDYALVSFQLLDVFSTDSMLRLRNHIDKANGY 271
            .|. |:..||:....|...:|::||..|:|.:|:||::|.|...|....:||..:..|||.|..|
  Rat   191 LDP-DMYSLLEDSTGDLRSQKFKKLTKAVCGLVDDYSMVRFLPYDQSDEESMNIVLQHIDFAIQY 254

  Fly   272 VYKAGEE 278
                ||:
  Rat   255 ----GED 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10222	NP_001287060.1	Gem1	19..193	CDD:224025	77/175 (44%)
CG10222	NP_001287060.1	ATP_bind_1	20..271	CDD:281079	101/252 (40%)
Gpn3	NP_973720.2	GPN3	4..249	CDD:349781	101/251 (40%)
		Gly-Pro-Asn (GPN)-loop, involved in dimer interface. /evidence=ECO:0000250\|UniProtKB:Q9UYR9	72..74		1/1 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	261..284
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D432496at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920