DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10222 and SPAC144.07c

DIOPT Version :9

Sequence 1:	NP_001287060.1	Gene:	CG10222 / 39504	FlyBaseID:	FBgn0036356	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_594668.1	Gene:	SPAC144.07c / 2542899	PomBaseID:	SPAC144.07c	Length:	315	Species:	Schizosaccharomyces pombe

Alignment Length:	272	Identity:	117/272 - (43%)
Similarity:	180/272 - (66%)	Gaps:	9/272 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QLIIGPPGSGKTTYCGEALKFYRELGRQVGVVNLDPANENMSYEPVLSVMELITVEDCMEHLKLG 82
            |:::|||||||:|||....:....:||...:|||||||:.:.|...:.:.:::.||...:...||
pombe     5 QVVVGPPGSGKSTYCFGMYQLLSAIGRSSIIVNLDPANDFIKYPCAIDIRKVLDVEMIQKDYDLG 69

  Fly    83 PNGALMHCAEYLADHLEDWLLPALRKLSATYNYFLFDCPGQVELYTHHNAMARIFERLERE-RYS 146
            |||||::..|.:..|:| |||..|:|  ...:|.:|||||||||:|:||::.:|.:.||:| .|.
pombe    70 PNGALIYAMEAIEYHVE-WLLKELKK--HRDSYVIFDCPGQVELFTNHNSLQKIIKTLEKELDYR 131

  Fly   147 LVTVNLIDSHYCSEPAKFIATLLMALNTMLRMSLPHVNVLSKADLLKKHETKLHFNVDYYTDVLD 211
            .|:|.|:|::.|:.|:.:::.||:.|..||::.:||||:|||||||..:.| |...:|::|:|.|
pombe   132 PVSVQLVDAYCCTNPSAYVSALLVCLKGMLQLDMPHVNILSKADLLCTYGT-LPMKLDFFTEVQD 195

  Fly   212 LKYLLDKLDDDPAMRKYRKLNAAICSMVEDYALVSFQLLDVFSTDSMLRLRNHIDKANGYVYKA- 275
            |.||...||.|..:::|..||.|||.:|||:.||||:::.|.:..||||:...||:|.||.|.:
pombe   196 LSYLAPLLDRDKRLQRYSDLNKAICELVEDFNLVSFEVVAVENKASMLRVLRKIDQAGGYAYGST 260

  Fly   276 ---GEEQTVNSL 284
               |:...||::
pombe   261 EIGGDAVWVNAV 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10222	NP_001287060.1	Gem1	19..193	CDD:224025	76/174 (44%)
CG10222	NP_001287060.1	ATP_bind_1	20..271	CDD:281079	110/251 (44%)
SPAC144.07c	NP_594668.1	Gem1	3..178	CDD:224025	77/175 (44%)
SPAC144.07c	NP_594668.1	ATP_bind_1	7..255	CDD:281079	110/251 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	215	1.000	Domainoid score	I582
eggNOG	1	0.900	-	-		E2759_KOG1533
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7006
Inparanoid	1	1.050	225	1.000	Inparanoid score	I885
OMA	1	1.010	-	-		QHG54489
OrthoFinder	1	1.000	-	-		FOG0005210
OrthoInspector	1	1.000	-	-		oto100462
orthoMCL	1	0.900	-	-		OOG6_102415
Panther	1	1.100	-	-	LDO	PTHR21231
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R520
SonicParanoid	1	1.000	-	-		X3724
TreeFam	1	0.960	-	-
	14	13.860