DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10222 and B0207.6

DIOPT Version :9

Sequence 1:	NP_001287060.1	Gene:	CG10222 / 39504	FlyBaseID:	FBgn0036356	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_491713.2	Gene:	B0207.6 / 172267	WormBaseID:	WBGene00015029	Length:	268	Species:	Caenorhabditis elegans

Alignment Length:	257	Identity:	108/257 - (42%)
Similarity:	164/257 - (63%)	Gaps:	8/257 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 YGQLIIGPPGSGKTTYCGEALKFYRELGRQVGVVNLDPANENMSYEPVLSVMELITVEDCMEHLK 80
            ||.|:||.||:||:|:|......:.:..|....:||||||:.|:|.|.:::.|:|||.|.|:.|.
Worm     2 YGVLVIGAPGAGKSTFCAGLTDIFSQTKRPFLTINLDPANDTMAYAPDVNITEMITVNDVMDRLG 66

  Fly    81 LGPNGALMHCAEYLADHLEDWLLPALRKLSATY-NYFLFDCPGQVELYTHHNAMARIFERLERER 144
            |||||||.:|.|.|..:. :||   |:|:.|.: .|.:.|||||:|||.....:.::...||:..
Worm    67 LGPNGALKYCIETLGANC-NWL---LQKIEANHKKYLIIDCPGQLELYKSEGELWKVIRFLEKSG 127

  Fly   145 YSLVTVNLIDSHYCSEPAKFIATLLMALNTMLRMSLPHVNVLSKADLLKKHETKLHFNVDYYTDV 209
            ..|..::|.||.|||:|:|||:..|..|.||:.|.:|.||.||||||..:..|   :::::::.:
Worm   128 VRLCALHLADSLYCSDPSKFISVALSTLATMVTMEMPQVNCLSKADLFSEDGT---YDLEFFSHL 189

  Fly   210 LDLKYLLDKLDDDPAMRKYRKLNAAICSMVEDYALVSFQLLDVFSTDSMLRLRNHIDKANGY 271
            .|:..|||.|::.|.:.||||||.|||.::.|:.||||..|.|.:.:||:::...:|.|||:
Worm   190 PDVNRLLDLLNEVPGLEKYRKLNEAICGVISDFDLVSFVPLAVENKESMMKVIQMVDAANGF 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10222	NP_001287060.1	Gem1	19..193	CDD:224025	77/174 (44%)
CG10222	NP_001287060.1	ATP_bind_1	20..271	CDD:281079	104/251 (41%)
B0207.6	NP_491713.2	Gem1	4..174	CDD:224025	75/173 (43%)
B0207.6	NP_491713.2	ATP_bind_1	6..251	CDD:281079	104/251 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167775
Domainoid	1	1.000	202	1.000	Domainoid score	I1747
eggNOG	1	0.900	-	-		E2759_KOG1533
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	211	1.000	Inparanoid score	I2366
Isobase	1	0.950	-	0	Normalized mean entropy	S760
OMA	1	1.010	-	-		QHG54489
OrthoDB	1	1.010	-	-		D432496at33208
OrthoFinder	1	1.000	-	-		FOG0005210
OrthoInspector	1	1.000	-	-		oto19851
orthoMCL	1	0.900	-	-		OOG6_102415
Panther	1	1.100	-	-	LDO	PTHR21231
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R520
SonicParanoid	1	1.000	-	-		X3724
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.750