DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10222 and gpn3

DIOPT Version :9

Sequence 1:	NP_001287060.1	Gene:	CG10222 / 39504	FlyBaseID:	FBgn0036356	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001007371.1	Gene:	gpn3 / 100000326	ZFINID:	ZDB-GENE-040724-141	Length:	285	Species:	Danio rerio

Alignment Length:	272	Identity:	106/272 - (38%)
Similarity:	162/272 - (59%)	Gaps:	17/272 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 PRYGQLIIGPPGSGKTTYCGEALKFYRELGRQVGVVNLDPANENMSYEPVLSVMELITVEDCME- 77
            |||.||::||.||||:|||...|:..:.|.|.|.|||||||.|:..|..:..:.|||.|:|.||
Zfish     2 PRYAQLVMGPAGSGKSTYCATMLEHCQALNRSVQVVNLDPAAEHFEYPVIADIRELIQVDDVMED 66

  Fly    78 -HLKLGPNGALMHCAEYLADHLEDWLLPALRKLSATYNYFLFDCPGQVELYTHHNAMARIFERLE 141
             .|:.||||.|:.|.||.:::. |||..:|..:..  :|.|||||||:|||||...|.::.|:|:
Zfish    67 DSLRFGPNGGLIFCMEYFSNNF-DWLEESLGHVED--DYILFDCPGQIELYTHLPVMKQLVEQLQ 128

  Fly   142 RERYSLVTVNLIDSHYCSEPAKFIATLLMALNTMLRMSLPHVNVLSKADLLKKHETKLHFNVDYY 206
            :..:.:..|.|:||.:..|..|||:.::.||:.|:.:.:|.||:::|.|||.....|   .::.|
Zfish   129 QWEFRVCGVFLVDSQFMVETFKFISGVMAALSAMVMLEIPQVNIMTKMDLLSPKAKK---EIEKY 190

  Fly   207 TDVLDLKYLLDKLDDDPAMR--KYRKLNAAICSMVEDYALVSFQLLDVFSTDSMLRLRNHIDKAN 269
            .|. |:..:::  |:..|:|  |:.||..|||.:::||::|.|...|....:.:..:..|||.:.
Zfish   191 LDP-DMYSMME--DNSVALRSKKFSKLTKAICGLIDDYSMVRFLPFDRTDEEGINIVLQHIDFSI 252

  Fly   270 GYVYKAGEEQTV 281
            .|    ||:..|
Zfish   253 QY----GEDLEV 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10222	NP_001287060.1	Gem1	19..193	CDD:224025	76/175 (43%)
CG10222	NP_001287060.1	ATP_bind_1	20..271	CDD:281079	97/254 (38%)
gpn3	NP_001007371.1	Gem1	1..192	CDD:224025	83/195 (43%)
		ATP_bind_1	8..254	CDD:281079	97/254 (38%)
		Gly-Pro-Asn (GPN)-loop, involved in dimer interface. /evidence=ECO:0000250\|UniProtKB:Q9UYR9	72..74		1/1 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D432496at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920