DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Poc1 and Daw1

DIOPT Version :9

Sequence 1:	NP_001261799.1	Gene:	Poc1 / 39502	FlyBaseID:	FBgn0036354	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001359172.1	Gene:	Daw1 / 71227	MGIID:	1923089	Length:	428	Species:	Mus musculus

Alignment Length:	285	Identity:	72/285 - (25%)
Similarity:	125/285 - (43%)	Gaps:	42/285 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 FTGHSGGITQLRFGPDGAQIATSSTDSTVILWNLNQAARCIRFASHSAPVNGVAWSPKGNLVASA 78
            |.||:..|..|.|.|....:||.|.|:|..||::......:....|.|.:..:::...|:.:.:.
Mouse   186 FRGHTAEIVCLSFNPQSTVVATGSMDTTAKLWDIQNGEEVVTLTGHLAEIISLSFDTSGDRIITG 250

  Fly    79 GHDRTVKIWEPKLRGVSGEFVAHSKAVRSVDFDSTGHLMLTASDDKSAKIWRVARRQFVSSFAQQ 143
            ..|.||.:|:..........:.|...:.|..|:....|:||.|.||:..:|.....::|::....
Mouse   251 SFDHTVVVWDASTGRKVHTLIGHCAEISSALFNWDCSLILTGSMDKTCMLWDATSGKYVATLTGH 315

  Fly   144 NNWVRSAKFSPNGKLVATASDDKSVRIYDVDSGECVRTFTEERAAPRQLAWHPWGNMLAVALGCN 208
            ::.:..:.|...|||:||||.|.:.|:|:..:.:||.
Mouse   316 DDEILDSCFDYTGKLIATASADGTARVYNATTRKCVT---------------------------- 352

  Fly   209 RIKIFDVSGSQLLQLYVVHSAPVNDVAFHPSGHFLLSGSDDRTIRILDLLEGRPIYTLTGHTDAV 273
                 .:.|         |...::.::|:|.|:.||:||.|:|.||.|:..|:.:..|.||||.:
Mouse   353 -----KLEG---------HEGEISKISFNPQGNRLLTGSSDKTARIWDVQTGQCLQVLEGHTDEI 403

  Fly   274 NAVAFSRDGDKFATGGSDRQLLVWQ 298
            .:.||:..|:...||..|....:|:
Mouse   404 FSCAFNYKGNIVITGSKDNSCRIWR 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Poc1	NP_001261799.1	WD40	10..298	CDD:238121	71/283 (25%)
		WD40	14..388	CDD:225201	72/285 (25%)
		WD40 repeat	22..58	CDD:293791	10/35 (29%)
		WD40 repeat	63..99	CDD:293791	5/35 (14%)
		WD40 repeat	106..140	CDD:293791	10/33 (30%)
		WD40 repeat	147..183	CDD:293791	13/35 (37%)
		WD40 repeat	189..224	CDD:293791	1/34 (3%)
		WD40 repeat	231..254	CDD:293791	9/22 (41%)
		WD40 repeat	273..297	CDD:293791	6/23 (26%)
Daw1	NP_001359172.1	WD40	99..133	CDD:197651
		WD40 repeat	109..145	CDD:293791
		WD40	139..428	CDD:238121	71/283 (25%)
		WD40 repeat	150..188	CDD:293791	1/1 (100%)
		WD40 repeat	194..230	CDD:293791	10/35 (29%)
		WD40 repeat	235..271	CDD:293791	5/35 (14%)
		WD40 repeat	278..313	CDD:293791	10/34 (29%)
		WD40 repeat	319..355	CDD:293791	13/68 (19%)
		WD40 repeat	361..397	CDD:293791	13/35 (37%)
		WD40 repeat	403..427	CDD:293791	6/23 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53955
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920