Protein Alignment Poc1 and Poc1a

DIOPT Version :10

• Sequence 1: NP_001261799.1
• Gene: Poc1 / 39502
• FlyBaseID: FBgn0036354
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_081630.2
• Gene: Poc1a / 70235
• MGIID: 1917485
• Length: 405
• Species: Mus musculus
• Alignment Length: 393
• Identity: 154/393 - (39%)
• Similarity: 237/393 - (60%)
• Gaps: 15/393 - (3%)

  Fly     7 DPALERHFTGHSGGITQLRFGPDGAQIATSSTDSTVILWNLNQAARCIRFASHSAPVNGVAWSPK 71
            ||:|||||.||...:|.:.|..:...:|:.|.|||:::|::...:|..||..|...|..|.:||.
Mouse     8 DPSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKPQSRAYRFTGHKDAVTCVNFSPS 72

  Fly    72 GNLVASAGHDRTVKIWEPKLRGVSGEFVAHSKAVRSVDFDSTGHLMLTASDDKSAKIWRVARRQF 136
            |:|:||...|:||:||.|.::|.|..|.||:..||||.|.|.|..::||||||:.|:|...|::|
Mouse    73 GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRF 137

  Fly   137 VSSFAQQNNWVRSAKFSPNGKLVATASDDKSVRIYDVDSGECVRTFTEERAAPRQLAWHPWGNML 201
            :.|..|..||||.|||||:|:|:.:|||||:|:::|..|.||:.::.|.......:.:||.|..:
Mouse   138 LFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCI 202

  Fly   202 AVALGCNRIKIFDVSGSQLLQLYVVHSAPVNDVAFHPSGHFLLSGSDDRTIRILDLLEGRPIYTL 266
            |.|...|.:|::|....:|||.|.:|||.||.::|||||::|::.|.|.|::||||:|||.:|||
Mouse   203 AAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTL 267

  Fly   267 TGHTDAVNAVAFSRDGDKFATGGSDRQLLVWQSNLHTYDASQFEAKSALASSSCESSGVSSKQSE 331
            .||......|||||.|:.||:||||.|::||:||....|....:|:.....:|  |||...|...
Mouse   268 HGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDYGDMKARRPPPLTS--SSGTLPKMDL 330

  Fly   332 GSSTSKSNDL-SIRIDPRQSLAYQLSEENFQVLDVSIESGSDLCSCSARLDEISKLLDSIDERVR 395
            .....:...| |::.:|::|::..      |.|..::|      ....:||.:::.:..:::|:.
Mouse   331 PVPPGRDRSLESVQGEPQESISMP------QTLTSTLE------HIVGQLDILTQTVSILEQRLT 383

  Fly   396 RLE 398
            ..|
Mouse   384 LTE 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poc1	NP_001261799.1	WD40	<7..298	CDD:441893	133/290 (46%)
		WD40 repeat	22..58	CDD:293791	11/35 (31%)
		WD40 repeat	63..99	CDD:293791	16/35 (46%)
		WD40 repeat	106..140	CDD:293791	16/33 (48%)
		WD40 repeat	147..183	CDD:293791	19/35 (54%)
		WD40 repeat	189..224	CDD:293791	11/34 (32%)
		WD40 repeat	231..254	CDD:293791	11/22 (50%)
		WD40 repeat	273..297	CDD:293791	13/23 (57%)
Poc1a	NP_081630.2	WD40	<7..298	CDD:441893	132/289 (46%)
		WD 1	17..56		11/38 (29%)
		WD40 repeat	23..59	CDD:293791	11/35 (31%)
		WD 2	59..98		17/38 (45%)
		WD40 repeat	64..100	CDD:293791	16/35 (46%)
		WD 3	101..140		19/38 (50%)
		WD40 repeat	107..142	CDD:293791	17/34 (50%)
		WD 4	143..182		22/38 (58%)
		WD40 repeat	148..184	CDD:293791	19/35 (54%)
		WD 5	185..224		11/38 (29%)
		WD40 repeat	190..226	CDD:293791	11/35 (31%)
		WD 6	227..266		21/38 (55%)
		WD40 repeat	232..255	CDD:293791	11/22 (50%)
		WD 7	269..308		20/38 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..352		9/40 (23%)