DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Poc1 and CG7568

DIOPT Version :9

Sequence 1:	NP_001261799.1	Gene:	Poc1 / 39502	FlyBaseID:	FBgn0036354	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001263071.1	Gene:	CG7568 / 43482	FlyBaseID:	FBgn0039673	Length:	482	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	71/294 - (24%)
Similarity:	121/294 - (41%)	Gaps:	45/294 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 FTGHSGGITQLRFGP-DGAQIATSSTDSTVILWNLNQAARCIRFASHSAPVNGVAWSPKGNLVAS 77
            |.||:..:....|.| ||..|||:|.|.:..::::..:....:...|.|.|....::..|.::.:
  Fly   220 FYGHTAELVAAEFHPVDGKSIATASLDGSARIYDVETSHELQQLTHHGAEVIAARFNRDGQMLLT 284

  Fly    78 AGHDRTVKIWEPKLRGVSGEFVAHSKAVRSVDFDSTGHLMLTASDDKSAKIWRVAR-RQFVSSFA 141
            ...|.:..||:.:.:.:..:...||..:.:..::.:|.|:.|.|.|.:|:||...: .|.:...|
  Fly   285 GSFDHSAAIWDVRSKSLGHQLRGHSAELSNCVWNFSGSLIATGSLDNTARIWDTRKLDQELYLAA 349

  Fly   142 QQNNWVRSAKFSPNGKLVATASDDKSVRIYDVDSGECVRTFTEERAAPRQLAWHPWGNMLAVALG 206
            :.::.|....|...|:|:||.|.|.:.|::.::..
  Fly   350 RHSDEVLDVSFDAAGQLLATCSSDCTARVWRLEGS------------------------------ 384

  Fly   207 CNRIKIFDVSGSQLLQLYVVHSAPVNDVAFHPSGHFLLSGSDDRTIRILDLLEGRPIYTLTGHTD 271
                     |..::|.|...||..|:.|.|.|||..||:.|.|.|.|:.....|:....|.||..
  Fly   385 ---------SELEMLSLMAGHSDEVSKVCFSPSGCMLLTASADNTARLWLTESGQCSQVLAGHEG 440

  Fly   272 AVNAVAFSRDGDKFATGGSDRQLLVWQSNLHTYD 305
            .|.:.|:|..||...|...|.....|:     ||
  Fly   441 EVFSCAYSYAGDAILTASKDNSCRFWR----XYD 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Poc1	NP_001261799.1	WD40	10..298	CDD:238121	68/285 (24%)
		WD40	14..388	CDD:225201	71/294 (24%)
		WD40 repeat	22..58	CDD:293791	9/36 (25%)
		WD40 repeat	63..99	CDD:293791	5/35 (14%)
		WD40 repeat	106..140	CDD:293791	9/34 (26%)
		WD40 repeat	147..183	CDD:293791	9/35 (26%)
		WD40 repeat	189..224	CDD:293791	2/34 (6%)
		WD40 repeat	231..254	CDD:293791	11/22 (50%)
		WD40 repeat	273..297	CDD:293791	7/23 (30%)
CG7568	NP_001263071.1	WD40	93..466	CDD:225201	68/284 (24%)
		WD40 repeat	122..158	CDD:293791
		WD40	154..467	CDD:238121	68/285 (24%)
		WD40 repeat	189..222	CDD:293791	1/1 (100%)
		WD40 repeat	228..265	CDD:293791	9/36 (25%)
		WD40 repeat	270..306	CDD:293791	5/35 (14%)
		WD40 repeat	314..348	CDD:293791	9/33 (27%)
		WD40 repeat	355..393	CDD:293791	11/76 (14%)
		WD40 repeat	400..436	CDD:293791	13/35 (37%)
		WD40 repeat	442..466	CDD:293791	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442330
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840