Protein Alignment Poc1 and WDR38

DIOPT Version :10

• Sequence 1: NP_001261799.1
• Gene: Poc1 / 39502
• FlyBaseID: FBgn0036354
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001263303.1
• Gene: WDR38 / 401551
• HGNCID: 23745
• Length: 315
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 92/338 - (27%)
• Similarity: 136/338 - (40%)
• Gaps: 54/338 - (15%)

  Fly    12 RHFTGHSGGITQLRFGPDGAQIATSSTDSTVILWNLNQAARCIRFASHSAPVNGVAWSPKGNLVA 76
            :.|..|.|.:....|.|||..:.|.|.|..|..|.........|...|:.||....:||.|:|.|
Human    15 KFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79

  Fly    77 SAGHDRTVKIWEPKLRGVSGEFVAHSKAVRSVDFDSTGHLMLTASDDKSAKIWRVARRQFVSSFA 141
            ||..|.||::|:          ||.:|.:|.:    .||
Human    80 SASCDCTVRLWD----------VARAKCLRVL----KGH-------------------------- 104

  Fly   142 QQNNWVRSAKFSPNGKLVATASDDKSVRIYDVDSGECVRTFTEERAAPRQLAWHPWGNMLAVALG 206
            |::  |.:..|||:.:.:|:...||.|.::||.||:.:|.....|.:.:...:.|..|.||....
Human   105 QRS--VETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSW 167

  Fly   207 CNRIKIFD---VSGSQLLQLYVVHSAPVNDVAFHPSGHFLLSGSDDRTIRILDLLEGRPIYTLTG 268
            .:.:.|:|   |:.:...|....|||.::.:.:..|| .|.|||.|:||.|........:..|.|
Human   168 DSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASG-LLASGSWDKTIHIWKPTTSSLLIQLKG 231

  Fly   269 HTDAVNAVAFSRDGDKFATGGSDRQLLVWQSN----LHTYDASQFEAKSALA----SSSCESSGV 325
            |...|.::|||.|....|:.|..|.:.||..|    |.|......:.....|    .....|...
Human   232 HVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKQGVLDVAHTCAFTPDGKILVSGAA 296

  Fly   326 SSKQSEGSSTSKS 338
            ...:.:.|.||||
Human   297 DQTRRQISRTSKS 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poc1	NP_001261799.1	WD40	<7..298	CDD:441893	81/288 (28%)
		WD40 repeat	22..58	CDD:293791	10/35 (29%)
		WD40 repeat	63..99	CDD:293791	12/35 (34%)
		WD40 repeat	106..140	CDD:293791	3/33 (9%)
		WD40 repeat	147..183	CDD:293791	13/35 (37%)
		WD40 repeat	189..224	CDD:293791	8/37 (22%)
		WD40 repeat	231..254	CDD:293791	9/22 (41%)
		WD40 repeat	273..297	CDD:293791	8/23 (35%)
WDR38	NP_001263303.1	WD40	<12..299	CDD:441893	87/326 (27%)
		WD 1	19..58		11/38 (29%)
		WD40 repeat	26..61	CDD:293791	10/34 (29%)
		WD 2	61..100		17/48 (35%)
		WD40 repeat	67..103	CDD:293791	15/49 (31%)
		WD 3	103..142		15/66 (23%)
		WD40 repeat	108..144	CDD:293791	13/35 (37%)
		WD 4	145..184		8/38 (21%)
		WD40 repeat	151..189	CDD:293791	8/37 (22%)
		WD 5	190..228		13/38 (34%)
		WD40 repeat	195..230	CDD:293791	10/35 (29%)
		WD 6	231..272		15/40 (38%)
		WD40 repeat	236..272	CDD:293791	13/35 (37%)
		WD 7	275..313		7/35 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..315		5/15 (33%)