Protein Alignment Poc1 and Poc1b

DIOPT Version :10

• Sequence 1: NP_001261799.1
• Gene: Poc1 / 39502
• FlyBaseID: FBgn0036354
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_082016.1
• Gene: Poc1b / 382406
• MGIID: 1918511
• Length: 476
• Species: Mus musculus
• Alignment Length: 417
• Identity: 157/417 - (37%)
• Similarity: 239/417 - (57%)
• Gaps: 50/417 - (11%)

  Fly     7 DPALERHFTGHSGGITQLRFGPDGAQIATSSTDSTVILWNLNQAARCIRFASHSAPVNGVAWSPK 71
            ||.|||.|.||...||...|.|:..||||:|.|:.::||:|...||..|:..|...|..:.:||:
Mouse     7 DPILERSFKGHKAAITSADFSPNCKQIATASWDTFLMLWSLKPHARAYRYVGHKDVVTSLQFSPQ 71

  Fly    72 GNLVASAGHDRTVKIWEPKLRGVSGEFVAHSKAVRSVDFDSTGHLMLTASDDKSAKIWRVARRQF 136
            |||:|||..||||::|....:|.|.||.||:..||||||.:.|.|::|||:|||.|:|.:.|::|
Mouse    72 GNLLASASRDRTVRLWVLDRKGKSSEFKAHTAPVRSVDFSADGQLLVTASEDKSIKVWSMFRQRF 136

  Fly   137 VSSFAQQNNWVRSAKFSPNGKLVATASDDKSVRIYDVDSGECVRTFTEERAAPRQLAWHPWGNML 201
            :.|..:..:|||.|||||:|:|:.:.|:||:::|:|..:.:||..|::.......:.::|.|..:
Mouse   137 LYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPNGTCI 201

  Fly   202 AVALGCNRIKIFDVSGSQLLQLYVVHSAPVNDVAFHPSGHFLLSGSDDRTIRILDLLEGRPIYTL 266
            |.|...:.:||:|:..::|||.|.|||..||.::|||.|:.|::.|.|.|:::|||:|||.||||
Mouse   202 ASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVKMLDLIEGRLIYTL 266

  Fly   267 TGHTDAVNAVAFSRDGDKFATGGSDRQLLVWQSN---LHTYDASQ------FEAKSALASSSCES 322
            .|||..|..|:||:||:...:||:|.|:|:|::|   ||..|..:      |||...|......|
Mouse   267 QGHTGPVFTVSFSKDGELLTSGGADAQVLIWRTNFIHLHCKDPKRNLKRLHFEASPHLLDIYPRS 331

  Fly   323 SGVSSKQSEGSSTSKSNDLSIRIDPRQSLAYQLSEENFQVLDV-SIES--------------GSD 372
            ......:.|          :|.|:|::.: ..|...:..|:|| |.:|              |.|
Mouse   332 PHSHEDRKE----------TIEINPKREV-MDLQSSSPPVVDVLSFDSTTMTDSTYRAVPGKGED 385

  Fly   373 LC----------SCSA-----RLDEIS 384
            :|          .||:     |.:::|
Mouse   386 ICRYFLNPLLMPECSSTTVKKRPEDVS 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poc1	NP_001261799.1	WD40	<7..298	CDD:441893	130/290 (45%)
		WD40 repeat	22..58	CDD:293791	15/35 (43%)
		WD40 repeat	63..99	CDD:293791	17/35 (49%)
		WD40 repeat	106..140	CDD:293791	17/33 (52%)
		WD40 repeat	147..183	CDD:293791	16/35 (46%)
		WD40 repeat	189..224	CDD:293791	10/34 (29%)
		WD40 repeat	231..254	CDD:293791	10/22 (45%)
		WD40 repeat	273..297	CDD:293791	11/23 (48%)
Poc1b	NP_082016.1	WD40	<5..300	CDD:441893	131/292 (45%)
		WD 1	16..55		17/38 (45%)
		WD40 repeat	21..58	CDD:293791	16/36 (44%)
		WD 2	58..97		17/38 (45%)
		WD40 repeat	63..100	CDD:293791	18/36 (50%)
		WD 3	100..139		20/38 (53%)
		WD40 repeat	106..142	CDD:293791	18/35 (51%)
		WD 4	142..181		17/38 (45%)
		WD40 repeat	147..182	CDD:293791	16/34 (47%)
		WD 5	183..223		9/39 (23%)
		WD40 repeat	190..225	CDD:293791	10/34 (29%)
		WD 6	226..265		20/38 (53%)
		WD40 repeat	231..267	CDD:293791	19/35 (54%)
		WD 7	268..307		18/38 (47%)
		WD40 repeat	273..299	CDD:293791	12/25 (48%)