DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Poc1 and CG10931

DIOPT Version :9

Sequence 1:	NP_001261799.1	Gene:	Poc1 / 39502	FlyBaseID:	FBgn0036354	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_611261.1	Gene:	CG10931 / 37024	FlyBaseID:	FBgn0034274	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	304	Identity:	79/304 - (25%)
Similarity:	136/304 - (44%)	Gaps:	49/304 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ALERHFTGHSGGITQLRFGPDGAQIATSSTDSTVILWNLNQAARCIR-FASHSAPVNGVAWSPKG 72
            |::....||||.:|.|:|..:|..:.:||.|..:.||:|: |.|||: .|.|...||.||||..|
  Fly    47 AIKHSLLGHSGCVTGLKFSSNGENLVSSSGDRLLKLWDLS-ATRCIQSLAGHGDGVNDVAWSAAG 110

  Fly    73 NLVASAGHDRTVKIWEPKLRGVSGEFVAHSKAVRSVDFDSTGHLMLTASDDKSAKIWRVARRQFV 137
             |:||...|.||::|:.:.:........||:...|..|:...:|:.:.|.|::.::|.|...:.:
  Fly   111 -LIASCSDDMTVRLWDARSKLCVKVLEGHSRYSFSCCFNPQANLLASTSFDETVRLWDVRTGKTL 174

  Fly   138 SSFAQQNNWVRSAKFSPNGKLVATASDDKSVRIYDVDSGECVRTFTEERAAPRQLAWHPWGNMLA 202
            .......:.:.|..|..:|.:..|:|.|..||::|..:|..::|..:
  Fly   175 KIVHAHQDPITSVDFHRDGNIFVTSSYDGLVRLWDSSTGHVLKTLVD------------------ 221

  Fly   203 VALGCNRIKIFDVSGSQLLQLYVVHSAPVNDVAFHPSGHFLLSGSDDRTIRILDLLEGRPIYTLT 267
                                   |.:.||..|.|.|:|.::||.:.:.|:|:.:..:.:.:.|..
  Fly   222 -----------------------VDNIPVGYVKFSPNGRYILSSTLNNTLRLWNYKKPKCMRTYR 263

  Fly   268 GHTD---AVNAVAFSRDGDKFATGGSDRQLLVWQSNLHTYDASQ 308
            ||.:   ..|:...:..|....:|..|..|.:|  ||.|.:..|
  Fly   264 GHLNEFYCSNSNFSTTGGIWIVSGSEDNTLCIW--NLQTRELVQ 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Poc1	NP_001261799.1	WD40	10..298	CDD:238121	73/291 (25%)
		WD40	14..388	CDD:225201	78/299 (26%)
		WD40 repeat	22..58	CDD:293791	14/36 (39%)
		WD40 repeat	63..99	CDD:293791	14/35 (40%)
		WD40 repeat	106..140	CDD:293791	7/33 (21%)
		WD40 repeat	147..183	CDD:293791	11/35 (31%)
		WD40 repeat	189..224	CDD:293791	0/34 (0%)
		WD40 repeat	231..254	CDD:293791	8/22 (36%)
		WD40 repeat	273..297	CDD:293791	5/23 (22%)
CG10931	NP_611261.1	WD40	<48..341	CDD:225201	78/303 (26%)
		WD40	49..341	CDD:238121	78/302 (26%)
		WD40 repeat	59..96	CDD:293791	14/37 (38%)
		WD40 repeat	102..137	CDD:293791	13/35 (37%)
		WD40 repeat	142..178	CDD:293791	7/35 (20%)
		WD40 repeat	185..220	CDD:293791	11/34 (32%)
		WD40 repeat	227..263	CDD:293791	10/35 (29%)
		WD40 repeat	271..309	CDD:293791	10/37 (27%)
		WD40 repeat	314..340	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442345
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840