Protein Alignment Poc1 and Nedd1

DIOPT Version :10

• Sequence 1: NP_001261799.1
• Gene: Poc1 / 39502
• FlyBaseID: FBgn0036354
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: XP_036011566.1
• Gene: Nedd1 / 17997
• MGIID: 97293
• Length: 669
• Species: Mus musculus
• Alignment Length: 426
• Identity: 95/426 - (22%)
• Similarity: 161/426 - (37%)
• Gaps: 97/426 - (22%)

  Fly    27 GP---DGAQIATSSTDSTVILWNLNQAARCIRFASHSAP--VNGVAWSPKGN--LVASAGHDRTV 84
            ||   :..:.|:|..|  |.:|:.:......:|..|::|  ::.:.||...|  :.||:..|:.|
Mouse    37 GPVMQENLRFASSGDD--VKIWDASFLTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIV 99

  Fly    85 KIWEPKLRGVSGEFVAHSKAVRSVDFDSTGHLMLTASDDKSAKIWRVARRQFVSSFAQQN----- 144
             :...|.:.|....:|..:....||.:||...:.:...:.:..||.:..::...|.....
Mouse   100 -VSSCKCKPVPLLELAEGQKQTCVDLNSTSMYLASGGLNNTVNIWDLKSKRLHRSLKDHKCEVTC 163

  Fly   145 ---NW-----------------------------------VRSAKFSPNGK-LVATASDDKSVRI 170
               ||                                   :|..|:|...| |:.:.||:..|.:
Mouse   164 VAYNWNDCYIASGSLSGEIILHSVTTNTSSTPFGHGSKQPIRHIKYSLFRKSLLGSVSDNGVVTL 228

  Fly   171 YDVDSGECVRTFTEERAAPRQ-LAWHPWGNMLAVALGCN-RIKIFDVSGSQLLQLYVVHSAPVND 233
            :||:|.....||.....||.. :.:.|...:|.|.:|.: ||.::|.|..:|::. :|...|:..
Mouse   229 WDVNSQSSYHTFDSTHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKT-LVADTPLTA 292

  Fly   234 VAFHPSGHFLLSGSDDRTIRILDL-LEGRPIYTLTGHTDAVNAVAFSRDGDKFATGGSDRQLLVW 297
            |.|.|.|..|..||....|...|| :...|:.|::.|..:|..:||.
Mouse   293 VDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQ------------------ 339

  Fly   298 QSNLHTYDASQFEAKSALASSSCESSGVSSKQS---EGSSTSKSNDLSIRIDPRQSLAYQLSEEN 359
                  |..|.  .|::|:..|...:...:|:|   ..||.:..|...:|..|..|:|..|.
Mouse   340 ------YSTSL--TKASLSKGSSNKATAVNKRSVPVSSSSGAAQNSGIVREAPSPSIATVLP--- 393

  Fly   360 FQVLDVSIESGSDLCSCSARL------DEISKLLDS 389
             |.:..::..||......|.|      |..||..|:
Mouse   394 -QPVTTALGKGSGAAQDEAGLARSKSTDIFSKETDA 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poc1	NP_001261799.1	WD40	<7..298	CDD:441893	71/324 (22%)
		WD40 repeat	22..58	CDD:293791	8/33 (24%)
		WD40 repeat	63..99	CDD:293791	9/37 (24%)
		WD40 repeat	106..140	CDD:293791	6/33 (18%)
		WD40 repeat	147..183	CDD:293791	12/36 (33%)
		WD40 repeat	189..224	CDD:293791	10/36 (28%)
		WD40 repeat	231..254	CDD:293791	8/22 (36%)
		WD40 repeat	273..297	CDD:293791	3/23 (13%)
Nedd1	XP_036011566.1	WD40	63..338	CDD:238121	62/276 (22%)
		WD40 repeat	76..113	CDD:293791	9/37 (24%)
		WD40 repeat	120..156	CDD:293791	7/35 (20%)
		WD40 repeat	162..199	CDD:293791	2/36 (6%)
		WD40 repeat	204..241	CDD:293791	12/36 (33%)
		WD40 repeat	249..285	CDD:293791	9/36 (25%)
		WD40 repeat	290..327	CDD:293791	12/36 (33%)