Protein Alignment CG10171 and TMEM19

DIOPT Version :9

• Sequence 1: NP_729888.1
• Gene: CG10171 / 39501
• FlyBaseID: FBgn0036353
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_060749.2
• Gene: TMEM19 / 55266
• HGNCID: 25605
• Length: 336
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 148/327 - (45%)
• Similarity: 227/327 - (69%)
• Gaps: 12/327 - (3%)

  Fly     7 VLFCGLSVPISLFMWLGNVALSKFWSSDFEGYPTESRVIPPVRWLFSTLAPLALMTVALRRRSVN 71
            ::...|.:.|||..|:.::..|.::.:        .|.|.|.|||||.:.|:.:::..|:::|::
Human    19 IVILSLIICISLAFWIISMTASTYYGN--------LRPISPWRWLFSVVVPVLIVSNGLKKKSLD 75

  Fly    72 RSGAALGILVAFILSIASHPFFASLVVFFFSSSRATKFRAHMKRRFESDFREGEGQRNWIQVLCN 136
            .|||..|::|.|||:||:..||.||::||.|||:.||::..:|:|.:|:::|| |||||:||.||
Human    76 HSGALGGLVVGFILTIANFSFFTSLLMFFLSSSKLTKWKGEVKKRLDSEYKEG-GQRNWVQVFCN 139

  Fly   137 GGMAAQLALLYLLDCGSGERAVDFAREYRSSWLGVAVMSAFACCNGDTWSSELGSVLSQRDPVSI 201
            |.:..:|||||:::.|.||..|||:::|.:||:.:::::|.||..||||:||:|.|||:..|..|
Human   140 GAVPTELALLYMIENGPGEIPVDFSKQYSASWMCLSLLAALACSAGDTWASEVGPVLSKSSPRLI 204

  Fly   202 ITWRRVPRGTNGGVSLLGVAVSLLGGLLVGFGYFVTVRYTVEAKMLLISPPQWPIIAFGGIAGLF 266
            .||.:||.||||||:::|:..|||||..||..||:|  ..:....|.||.||||||||||:|||.
Human   205 TTWEKVPVGTNGGVTVVGLVSSLLGGTFVGIAYFLT--QLIFVNDLDISAPQWPIIAFGGLAGLL 267

  Fly   267 GSLLDSVLGGLLQFSGINEE-GKIVDTPGKGVRHVSGLRILDNHSVNLISSIVTGVTIPLLAQRF 330
            ||::||.||..:|::|::|. |.:|::|....||::|..||||::|||.||::..:.:|..|..|
Human   268 GSIVDSYLGATMQYTGLDESTGMVVNSPTNKARHIAGKPILDNNAVNLFSSVLIALLLPTAAWGF 332

  Fly   331 WP 332
            ||
Human   333 WP 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10171	NP_729888.1	DUF92	59..318	CDD:280173	128/259 (49%)
TMEM19	NP_060749.2	DUF92	63..320	CDD:280173	128/259 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159294
Domainoid	1	1.000	271	1.000	Domainoid score	I1820
eggNOG	1	0.900	-	-		E1_COG1836
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10107
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2667
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55191
OrthoDB	1	1.010	-	-		D1476886at2759
OrthoFinder	1	1.000	-	-		FOG0005785
OrthoInspector	1	1.000	-	-		oto90256
orthoMCL	1	0.900	-	-		OOG6_102547
Panther	1	1.100	-	-	LDO	PTHR13353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4174
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770