DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10171 and Tmem19

DIOPT Version :9

Sequence 1:	NP_729888.1	Gene:	CG10171 / 39501	FlyBaseID:	FBgn0036353	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	XP_006241409.1	Gene:	Tmem19 / 299800	RGDID:	735209	Length:	350	Species:	Rattus norvegicus

Alignment Length:	327	Identity:	147/327 - (44%)
Similarity:	221/327 - (67%)	Gaps:	12/327 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VLFCGLSVPISLFMWLGNVALSKFWSSDFEGYPTESRVIPPVRWLFSTLAPLALMTVALRRRSVN 71
            ::...|.:.|||..|:.::..|.::.|        .|.:.|.|||||.:..:.:.....:::|::
  Rat    33 IVILSLIICISLAFWIMSMTASTYYGS--------LRPVSPWRWLFSVVVSVVISCNGFKKKSLD 89

  Fly    72 RSGAALGILVAFILSIASHPFFASLVVFFFSSSRATKFRAHMKRRFESDFREGEGQRNWIQVLCN 136
            .|||..|::|.|||:||:..||.||::||.:||:.||:|..||:|.:|:::|| |||||:||.||
  Rat    90 HSGALGGLVVGFILTIANFSFFTSLLMFFLTSSKLTKWRGEMKKRLDSEYKEG-GQRNWVQVFCN 153

  Fly   137 GGMAAQLALLYLLDCGSGERAVDFAREYRSSWLGVAVMSAFACCNGDTWSSELGSVLSQRDPVSI 201
            ||:..:|||||:::.|.||..:|||:::.:||:.:::::|.|...||||:||:..|||:..|..|
  Rat   154 GGVPTELALLYMIENGPGEMPIDFAKQHTASWMCLSLLAALASSAGDTWASEVAPVLSKSSPRLI 218

  Fly   202 ITWRRVPRGTNGGVSLLGVAVSLLGGLLVGFGYFVTVRYTVEAKMLLISPPQWPIIAFGGIAGLF 266
            .||.:||.||||||:.:|:..|||||..||..||:|  ..|....|.||.||||:|||||:|||.
  Rat   219 TTWEKVPVGTNGGVTAVGLVSSLLGGTFVGLAYFLT--QLVFVNDLDISAPQWPLIAFGGLAGLL 281

  Fly   267 GSLLDSVLGGLLQFSGINEE-GKIVDTPGKGVRHVSGLRILDNHSVNLISSIVTGVTIPLLAQRF 330
            ||::||.||..:||||::|. |.:|.:|.:..:|:||..||||::|||.||::..:.:|..|..|
  Rat   282 GSIVDSFLGATMQFSGLDESTGLVVSSPTQETKHISGKPILDNNAVNLFSSVLVALLLPTAASGF 346

  Fly   331 WP 332
            ||
  Rat   347 WP 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10171	NP_729888.1	DUF92	59..318	CDD:280173	128/259 (49%)
Tmem19	XP_006241409.1	DUF92	82..334	CDD:280173	128/254 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353320
Domainoid	1	1.000	265	1.000	Domainoid score	I1829
eggNOG	1	0.900	-	-		E1_COG1836
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10107
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2624
OMA	1	1.010	-	-		QHG55191
OrthoDB	1	1.010	-	-		D1476886at2759
OrthoFinder	1	1.000	-	-		FOG0005785
OrthoInspector	1	1.000	-	-		otm45599
orthoMCL	1	0.900	-	-		OOG6_102547
Panther	1	1.100	-	-	LDO	PTHR13353
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4174
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770