DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment caps and zgc:153913

DIOPT Version :9

Sequence 1:	NP_001303391.1	Gene:	caps / 39493	FlyBaseID:	FBgn0023095	Length:	811	Species:	Drosophila melanogaster
Sequence 2:	NP_001073448.1	Gene:	zgc:153913 / 559700	ZFINID:	ZDB-GENE-061103-397	Length:	496	Species:	Danio rerio

Alignment Length:	479	Identity:	113/479 - (23%)
Similarity:	192/479 - (40%)	Gaps:	107/479 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LCLCLVLATLPVALGLANCPNGCECDDDTLMVNCGEGTLDVLPIALNPAIQRLVIKNNKLKTIDS 89
            ||..::|..:.:..|:. ||..|:|...:.:| |.:..:..||:.::..::.|::..:.:..:|
Zfish     4 LCAVVLLVLIHLYCGVC-CPEPCQCFSGSKLV-CSDDRMKSLPVNISTQVRELIVVASGIPDLD- 65

  Fly    90 SMQFYAQLTFLDLSFNDMLTIPERSFAYHAKLQELHLDHNKIGQVSNKTFLGLSTISVLNLRGNL 154
                                  ::||....:|.:|...:..:..||.:.|..|..:..|.:.||:
Zfish    66 ----------------------QQSFPETLRLSKLVFLNGMLKSVSGEAFERLVELRELEISGNI 108

  Fly   155 I-AELEYRTFSPMVKLAELNLGQNRISHIDPHALDGLDNLRVLYLDDNTLTTVPGELTFQALHSL 218
            . ..|:.:|||.:..|..|.|..|::|.:|......|..|.:|.|..|.|:.:.|.| ||.||.|
Zfish   109 CWMSLDIQTFSSLTNLTRLLLNNNKLSGVDAGLFHSLHQLEMLQLRGNGLSFLSGRL-FQRLHRL 172

  Fly   219 AELYLGTNSFMTIPGGAFQDLKGLTRLDLRGAGLHNISGDALKGLVSLRFLDLSDNRLPAIPTAA 283
            .||.|..|...::....||:..                        .||.|.|..|::|.:|...
Zfish   173 QELDLSFNQISSLSTELFQNNS------------------------ELRVLSLQANKIPNLPDGI 213

  Fly   284 FQRLGRLEQLNIGQNDFEVISSGAFSG----------------------LRELRHLELTGAQRLR 326
            |..|..|::||:..|...|::.|:|..                      |..:.:|:|: ...|.
Zfish   214 FTHLDHLQELNLRSNLIRVLTPGSFPASLKTLILKKNLLEKLTNAVFHTLHYITYLDLS-QNSLT 277

  Fly   327 RVESGAFSGNTNLEHLNLSSNKQLNELSSIALGGLPHLSTVVLKANQLSSLDEGLV-PWADLQTL 390
            .|.:..|....:||.|:||.|: ::.|:.....||..:.:|.|:.|.|.|:|..|: ...|||.|
Zfish   278 EVPADLFQNLISLETLDLSENR-ISTLAGSVFKGLFSIKSVYLQKNSLISVDAHLLKDQHDLQLL 341

  Fly   391 DLSE------------------------NPFECDCRLL----WLRHLLVSRNASGQYAPVICAYP 427
            |||.                        ||:.|||.:.    ||::   :.......:.|.|..|
Zfish   342 DLSNNSLRSIPSGFFEDLDFQCVFELRGNPWSCDCGIHYFYDWLKY---NHKHVKDLSRVSCEAP 403

  Fly   428 TALRDLPLAHLAEPLLGCAHGAAS 451
            ..::...|..:....|.|:..::|
Zfish   404 ELIQGHNLRSVDREQLVCSRNSSS 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	2/20 (10%)
		LRR_8	96..155	CDD:290566	11/58 (19%)
		leucine-rich repeat	97..120	CDD:275380	2/22 (9%)
		leucine-rich repeat	121..144	CDD:275380	6/22 (27%)
		LRR_8	143..201	CDD:290566	17/58 (29%)
		leucine-rich repeat	145..168	CDD:275380	7/23 (30%)
		LRR_RI	147..397	CDD:238064	78/297 (26%)
		leucine-rich repeat	169..192	CDD:275380	7/22 (32%)
		leucine-rich repeat	193..217	CDD:275380	10/23 (43%)
		LRR_8	217..276	CDD:290566	12/58 (21%)
		leucine-rich repeat	218..241	CDD:275380	7/22 (32%)
		leucine-rich repeat	242..265	CDD:275380	0/22 (0%)
		LRR_8	265..321	CDD:290566	19/77 (25%)
		leucine-rich repeat	266..289	CDD:275380	9/22 (41%)
		leucine-rich repeat	290..313	CDD:275380	8/44 (18%)
		LRR_8	312..374	CDD:290566	17/61 (28%)
		leucine-rich repeat	314..335	CDD:275380	5/20 (25%)
		leucine-rich repeat	339..363	CDD:275380	9/23 (39%)
		LRRCT	395..445	CDD:214507	12/53 (23%)
zgc:153913	NP_001073448.1	leucine-rich repeat	75..98	CDD:275380	6/22 (27%)
		LRR_RI	141..>350	CDD:238064	64/235 (27%)
		LRR_8	147..206	CDD:290566	23/83 (28%)
		leucine-rich repeat	148..171	CDD:275380	10/23 (43%)
		leucine-rich repeat	172..195	CDD:275380	7/46 (15%)
		LRR_8	194..252	CDD:290566	16/81 (20%)
		leucine-rich repeat	196..219	CDD:275380	9/22 (41%)
		leucine-rich repeat	220..241	CDD:275380	7/20 (35%)
		leucine-rich repeat	242..265	CDD:275380	1/22 (5%)
		leucine-rich repeat	266..289	CDD:275380	5/23 (22%)
		LRR_8	267..324	CDD:290566	17/58 (29%)
		leucine-rich repeat	290..313	CDD:275380	9/23 (39%)
		leucine-rich repeat	314..337	CDD:275380	7/22 (32%)
		leucine-rich repeat	338..359	CDD:275380	6/20 (30%)
		TPKR_C2	370..>404	CDD:301599	9/36 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D187891at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920