Protein Alignment caps and lingo4b

DIOPT Version :9

• Sequence 1: NP_001303391.1
• Gene: caps / 39493
• FlyBaseID: FBgn0023095
• Length: 811
• Species: Drosophila melanogaster
• Sequence 2: NP_001082850.1
• Gene: lingo4b / 559074
• ZFINID: ZDB-GENE-091214-3
• Length: 604
• Species: Danio rerio
• Alignment Length: 656
• Identity: 171/656 - (26%)
• Similarity: 257/656 - (39%)
• Gaps: 173/656 - (26%)

  Fly    16 GQ--AFSLCLCLCLCLVLATLPVALGLANCPNGCECDDDTLMVNCGEGTLDVLPIALNPAIQRLV 78
            ||  |:::.|..||.|..|.||       ||..|.|..|.|.|||....|..:|..|....:||.
Zfish     7 GQRGAWTVLLLWCLNLSAADLP-------CPQRCSCSRDPLEVNCSSRHLTAVPEGLPTNAKRLD 64

  Fly    79 IKNNKLKTIDSSMQF--YAQLTFLDLSFNDMLTIPERSFAYHAKLQELHLDHNKIGQVSNKTFLG 141
            :..|:|||: :..||  .::|..||||.|.:..|...:|.....|:.|.:.:|::..:....|.|
Zfish    65 LSGNQLKTL-ARRQFSSLSKLEDLDLSENIISMIEVETFQGLKNLRYLRIKNNRLKILPVGVFSG 128

  Fly   142 LSTISVLNLRGN-LIAELEYRTFSPMVKLAELNLGQNRISHIDPHALDGLDNLRVLYLDDNTLTT 205
            ||.:..|::..| ::..|:| ||..|:.|.:|:.|:|.:..|...|..||..|:.|.:|.:.||:
Zfish   129 LSNLRRLDISENEILVFLDY-TFRDMINLQQLDAGENDLVFISQRAFVGLQALKELNVDRSNLTS 192

  Fly   206 VPGELTFQALHSLAELYLGTNSFMTIPGGAFQDLKGLTRLD-LRGAGLHNISGDALKGLVSLRFL 269
            :|.|...| |.||.:|.|...:...:|..||:.|..|..|. |..:.|..::.::|.|| :|..|
Zfish   193 IPTEALSQ-LQSLTKLRLRKLTISVLPNNAFRRLHQLRTLQILHWSSLEMLNSNSLVGL-NLTTL 255

  Fly   270 DLSDNRLPAIPTAAFQRLGRLEQLNIGQNDFEVISSGAFSGLRELRHLELTGAQRLRRVESGAFS 334
            .|::..|.|||.:..:.|..|:.|::..|....|.......|..|:.|.|.|. .|.|:|.|||.
Zfish   256 VLTNCNLSAIPYSPLRHLAYLQYLDLSYNPITSIQGNLLGDLLRLQELHLVGG-NLLRIEPGAFR 319

  Fly   335 GNTNLEHLNLSSNKQLNELSSIALGGLPHLSTVVLKANQLSSLDEGLV-PWADLQTLDLSENPFE 398
            |.:....||:|||:                         ||:|:|... ...:||||.|..||..
Zfish   320 GLSRFRLLNVSSNR-------------------------LSTLEESAFHSVGNLQTLRLDRNPLA 359

  Fly   399 CDCRLLWLRHLLVSRNASGQYAPVICAYPT---------ALRDLPLAHLAEPLLGCAHGAASKQA 454
            |||||||:.......:..|:       .||         |.||...|.|.
Zfish   360 CDCRLLWVMRRRRRLDFDGR-------QPTCSPLNHQRKAFRDFSEAELP--------------- 402

  Fly   455 IIGILVVACAALITTLALVLYTCRHR--IREMLKGHSALGRKEREYQKTFSDEEYMSRPPPGGGG 517
                              |::|||..  :...|:..|.:                      .|..
Zfish   403 ------------------VVFTCRQAQILNRQLQDISVI----------------------EGMR 427

  Fly   518 VH--PAAGGYPYIAGNSRMIPVTELXLEAPPPPQLRGRGGGGGASTASGAVQQLQVPSAVDQASN 580
            ||  ..|.||                    |.|.:........|.:::|.|:.|         :|
Zfish   428 VHFDCKADGY--------------------PSPSITWLSAQQSALSSAGRVRVL---------TN 463

  Fly   581 SFAQLSHIHYMTNNGQQQQAQQQQSTSKMHHSQQDMRLLACNGGKPL--NATSLPRHRPPVVQES 643
            ...|:|:            ||.|.|.:.:           |:.....  ::.|:..|...:.|..
Zfish   464 GSLQISY------------AQVQDSGTYL-----------CSAANAAGNDSISVSLHVEGLPQNR 505

  Fly   644 TLSHYS 649
            |:|::|
Zfish   506 TVSYFS 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	8/22 (36%)
		LRR_8	96..155	CDD:290566	17/59 (29%)
		leucine-rich repeat	97..120	CDD:275380	8/22 (36%)
		leucine-rich repeat	121..144	CDD:275380	6/22 (27%)
		LRR_8	143..201	CDD:290566	19/58 (33%)
		leucine-rich repeat	145..168	CDD:275380	7/23 (30%)
		LRR_RI	147..397	CDD:238064	78/252 (31%)
		leucine-rich repeat	169..192	CDD:275380	8/22 (36%)
		leucine-rich repeat	193..217	CDD:275380	9/23 (39%)
		LRR_8	217..276	CDD:290566	18/59 (31%)
		leucine-rich repeat	218..241	CDD:275380	7/22 (32%)
		leucine-rich repeat	242..265	CDD:275380	7/23 (30%)
		LRR_8	265..321	CDD:290566	16/55 (29%)
		leucine-rich repeat	266..289	CDD:275380	8/22 (36%)
		leucine-rich repeat	290..313	CDD:275380	5/22 (23%)
		LRR_8	312..374	CDD:290566	16/61 (26%)
		leucine-rich repeat	314..335	CDD:275380	10/20 (50%)
		leucine-rich repeat	339..363	CDD:275380	5/23 (22%)
		LRRCT	395..445	CDD:214507	17/58 (29%)
lingo4b	NP_001082850.1	LRRNT	28..61	CDD:214470	13/39 (33%)
		leucine-rich repeat	41..62	CDD:275380	6/20 (30%)
		LRR	<56..304	CDD:227223	77/251 (31%)
		leucine-rich repeat	63..83	CDD:275380	7/20 (35%)
		leucine-rich repeat	84..107	CDD:275380	8/22 (36%)
		leucine-rich repeat	108..131	CDD:275380	6/22 (27%)
		leucine-rich repeat	132..155	CDD:275380	7/23 (30%)
		leucine-rich repeat	156..179	CDD:275380	8/22 (36%)
		leucine-rich repeat	180..203	CDD:275380	9/23 (39%)
		leucine-rich repeat	204..251	CDD:275380	14/47 (30%)
		leucine-rich repeat	228..250	CDD:275380	5/21 (24%)
		leucine-rich repeat	252..275	CDD:275380	8/22 (36%)
		leucine-rich repeat	276..297	CDD:275380	4/20 (20%)
		LRR_8	299..358	CDD:316378	26/84 (31%)
		leucine-rich repeat	300..321	CDD:275380	10/21 (48%)
		leucine-rich repeat	324..344	CDD:275380	9/44 (20%)
		I-set	415..498	CDD:254352	23/156 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5661
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940