Protein Alignment caps and Tl

DIOPT Version :10

• Sequence 1: NP_001303391.1
• Gene: caps / 39493
• FlyBaseID: FBgn0023095
• Length: 811
• Species: Drosophila melanogaster
• Sequence 2: NP_001262995.1
• Gene: Tl / 43222
• FlyBaseID: FBgn0262473
• Length: 1117
• Species: Drosophila melanogaster
• Alignment Length: 528
• Identity: 120/528 - (22%)
• Similarity: 192/528 - (36%)
• Gaps: 126/528 - (23%)

  Fly    28 CLVLATLPVA-----LGLANCPNGCECDDDTLMVNCGEGTLDVLPIALNPAIQRLVIKNNKLKTI 87
            |::....|:|     ||:.: |.....:.|.|.:|.....||.|     ..::|......:|..|
  Fly   107 CMLPGHTPIASILDYLGIVS-PTTLIFESDNLGMNITRQHLDRL-----HGLKRFRFTTRRLTHI 165

  Fly    88 D----------SSMQFYA--------------QLTFLDLSFNDMLTIPERSFAYHAKLQELHLDH 128
            .          |.::..|              .|..::...|.:..:|...|....||::|:|..
  Fly   166 PANLLTDMRNLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLKQLNLWS 230

  Fly   129 NKIGQVSNKTFLGLSTISVLNLRGNLIAELEYRTFSPMVKLAELNLGQNRISHIDPHALDGLDNL 193
            |::..::...|.|.:::..:::..|.|.:|.:..|:.:..:.::||..|....:.....|...:|
  Fly   231 NQLHNLTKHDFEGATSVLGIDIHDNGIEQLPHDVFAHLTNVTDINLSANLFRSLPQGLFDHNKHL 295

  Fly   194 RVLYLDDN--TLTTVPGEL-----TFQALHSLAELYLGTNSFMTIPGGAFQDLKGLTRLDLRGAG 251
            ..:.|.:|  .|.|:|..|     ..|.|...|||       .::||..|:....:|.:.|....
  Fly   296 NEVRLMNNRVPLATLPSRLFANQPELQILRLRAEL-------QSLPGDLFEHSTQITNISLGDNL 353

  Fly   252 LHNISGDALKGLVSLRFLDLSDNRLPAIPTAAFQRLGRLEQLNIGQNDFEVISSGAFSGLRELRH 316
            |..:....|:..|:|..||||:|||..:|.:.|.....|..|.:..|....||...||.|..|..
  Fly   354 LKTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFAHTTNLTDLRLEDNLLTGISGDIFSNLGNLVT 418

  Fly   317 LELTGAQRLRRVESGAFSGNTNLEHLNLSSNK--------------------------------- 348
            |.:: ..|||.::|.||.....|.||:|..|.
  Fly   419 LVMS-RNRLRTIDSRAFVSTNGLRHLHLDHNDIDLQQPLLDIMLQTQINSPFGYMHGLLTLNLRN 482

  Fly   349 ---------------QLNEL-------SSIALGGLPHLSTVVLKANQLSS------------LDE 379
                           ||.||       ||:....|..||...|..|...:            |.|
  Fly   483 NSIIFVYNDWKNTMLQLRELDLSYNNISSLGYEDLAFLSQNRLHVNMTHNKIRRIALPEDVHLGE 547

  Fly   380 GLVPWADLQTLDLSENPFECDCRLLWLRHLL-------VSRNASGQYAPVICAYPTALRDLPLAH 437
            |..  .:|..:||::||..|||.:||...|:       .||....:...::|:.|..|...|:..
  Fly   548 GYN--NNLVHVDLNDNPLVCDCTILWFIQLVRGVHKPQYSRQFKLRTDRLVCSQPNVLEGTPVRQ 610

  Fly   438 LAEPLLGC 445
            :....|.|
  Fly   611 IEPQTLIC 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	5/44 (11%)
		LRR_8	96..155	CDD:404697	12/58 (21%)
		leucine-rich repeat	97..120	CDD:275380	4/22 (18%)
		leucine-rich repeat	121..144	CDD:275380	6/22 (27%)
		LRR	135..>398	CDD:443914	80/336 (24%)
		leucine-rich repeat	145..168	CDD:275380	4/22 (18%)
		leucine-rich repeat	169..192	CDD:275380	4/22 (18%)
		leucine-rich repeat	193..217	CDD:275380	9/30 (30%)
		leucine-rich repeat	218..241	CDD:275380	6/22 (27%)
		leucine-rich repeat	242..265	CDD:275380	4/22 (18%)
		leucine-rich repeat	266..289	CDD:275380	10/22 (45%)
		leucine-rich repeat	290..313	CDD:275380	8/22 (36%)
		leucine-rich repeat	314..335	CDD:275380	8/20 (40%)
		leucine-rich repeat	339..363	CDD:275380	12/78 (15%)
		LRRCT	395..445	CDD:214507	15/56 (27%)
Tl	NP_001262995.1	LRR_8	174..233	CDD:404697	11/58 (19%)
		leucine-rich repeat	176..198	CDD:275380	2/21 (10%)
		leucine-rich repeat	199..222	CDD:275380	4/22 (18%)
		LRR	222..576	CDD:443914	90/363 (25%)
		leucine-rich repeat	223..270	CDD:275380	10/46 (22%)
		leucine-rich repeat	271..294	CDD:275380	4/22 (18%)
		leucine-rich repeat	295..320	CDD:275380	7/24 (29%)
		leucine-rich repeat	321..343	CDD:275380	8/28 (29%)
		leucine-rich repeat	344..367	CDD:275380	4/22 (18%)
		leucine-rich repeat	368..391	CDD:275380	10/22 (45%)
		leucine-rich repeat	392..415	CDD:275380	8/22 (36%)
		leucine-rich repeat	416..439	CDD:275380	8/23 (35%)
		leucine-rich repeat	440..474	CDD:275380	5/33 (15%)
		leucine-rich repeat	475..498	CDD:275380	0/22 (0%)
		leucine-rich repeat	499..520	CDD:275380	6/20 (30%)
		leucine-rich repeat	523..552	CDD:275380	5/30 (17%)
		LRRCT	561..619	CDD:214507	16/58 (28%)
		LRRNT	631..667	CDD:214470
		PPP1R42	<660..752	CDD:455733
		leucine-rich repeat	664..693	CDD:275380
		leucine-rich repeat	694..715	CDD:275380
		leucine-rich repeat	716..737	CDD:275380
		LRRCT	751..800	CDD:214507
		TIR	858..996	CDD:214587