DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment caps and CG32055

DIOPT Version :9

Sequence 1:	NP_001303391.1	Gene:	caps / 39493	FlyBaseID:	FBgn0023095	Length:	811	Species:	Drosophila melanogaster
Sequence 2:	NP_729599.1	Gene:	CG32055 / 39188	FlyBaseID:	FBgn0052055	Length:	534	Species:	Drosophila melanogaster

Alignment Length:	505	Identity:	121/505 - (23%)
Similarity:	187/505 - (37%)	Gaps:	126/505 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 ECDDDTLMVNCGEGTLDVLPIALNPAIQRLVIKNNK-LKTI----------DSSMQFYAQLTFLD 101
            ||:|      .|.|:.....|.....:.|.|.||.| :|.:          |..:...:.|..||
  Fly    22 ECED------LGNGSYLCREIESFEQLNRYVGKNWKSVKVVNEHTGIERAEDGELPGLSTLLQLD 80

  Fly   102 LSFNDMLTIPERSFAYHAKLQELHLDHNKIGQVSNKTFLGLSTISVLNLRGNLIAELEYRTFSPM 166
            ||.:..:|:.|:.......||:|:|.|.::.::.::.|...|.:...::..|.|..:..:..|..
  Fly    81 LSESGGVTLGEKGLQDFKALQKLNLTHAQLDELKSEQFPNPSEMINFDVSYNDILAITTKLMSGF 145

  Fly   167 VKLAELNLGQNRISHIDPHALDGLDNLRVLYLDDNTLTTVP-GE---LTF--------------- 212
            ..|...|..:|.|:.|:|:|...:.|||.|.|..|....:. ||   |.|
  Fly   146 GNLVYANFSENLIAVIEPNAFRHMKNLRFLDLTTNYQENITLGENANLRFLSISNNNLRDFQWCH 210

  Fly   213 -QALHSLAELYLGTNSFMTIPGGAFQDLKGLTRLDLRGAGLHNISGDALKG---LVSLRFLDLSD 273
             :.|..|.||:|.:|....:..|.|..|..|..|::....|..|.......   :..|..||.|.
  Fly   211 LRVLPKLEELHLHSNWLEHLDMGIFYALPNLRVLNVSNNNLFEIKRTLFMAPGEIAPLELLDYSS 275

  Fly   274 NRLPAIPTAAFQRLGRLEQLNIGQNDFEVISSGAFSGLRELRHLELTGAQRLRRVESGAFSGNTN 338
            |.:..:..:.|.||.:|..||:..|....|...||.||..|:.|.|.| .::..:....|:..|.
  Fly   276 NIVKVLDDSVFCRLKKLRTLNLWLNQINRIHPRAFLGLSSLQTLHLQG-NKISILPDDVFANLTA 339

  Fly   339 LEHLNLS-------------------------SNKQLNELSSIALGGLPHLSTVVLKANQLSSLD 378
            ||.|:||                         ||..:.:|..:||..:|.:..:.|:.|:|.|||
  Fly   340 LEKLDLSKNNIQKLGLRVFGERILRKLIYLDLSNNYIADLHPLALSSMPFIKELRLRRNRLVSLD 404

  Fly   379 -EGLVPWADLQTLDLSE------------------------------------------------ 394
             ....|...||.|.::|
  Fly   405 LRMFAPLRQLQLLTINENRLEEIDGEILDTLDRLNHLELNNNRLTFLPDLKSSQNLLQLRNITLE 469

  Fly   395 -NPFECDCR---LLWL--RHLLVSRNASGQYA---PVICAYP--TALRDL 433
             ||::|.|.   ..||  ||:..:|.:|..::   |:....|  ..||||
  Fly   470 GNPWQCLCLDEITSWLNGRHVSYARPSSAYFSGRKPLCVVTPMDKCLRDL 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	7/31 (23%)
		LRR_8	96..155	CDD:290566	15/58 (26%)
		leucine-rich repeat	97..120	CDD:275380	7/22 (32%)
		leucine-rich repeat	121..144	CDD:275380	6/22 (27%)
		LRR_8	143..201	CDD:290566	16/57 (28%)
		leucine-rich repeat	145..168	CDD:275380	3/22 (14%)
		LRR_RI	147..397	CDD:238064	79/347 (23%)
		leucine-rich repeat	169..192	CDD:275380	7/22 (32%)
		leucine-rich repeat	193..217	CDD:275380	10/43 (23%)
		LRR_8	217..276	CDD:290566	17/61 (28%)
		leucine-rich repeat	218..241	CDD:275380	8/22 (36%)
		leucine-rich repeat	242..265	CDD:275380	4/25 (16%)
		LRR_8	265..321	CDD:290566	20/55 (36%)
		leucine-rich repeat	266..289	CDD:275380	8/22 (36%)
		leucine-rich repeat	290..313	CDD:275380	9/22 (41%)
		LRR_8	312..374	CDD:290566	19/86 (22%)
		leucine-rich repeat	314..335	CDD:275380	5/20 (25%)
		leucine-rich repeat	339..363	CDD:275380	10/48 (21%)
		LRRCT	395..445	CDD:214507	16/49 (33%)
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380	7/22 (32%)
		leucine-rich repeat	100..123	CDD:275380	6/22 (27%)
		LRR_8	128..180	CDD:290566	15/51 (29%)
		leucine-rich repeat	128..147	CDD:275380	3/18 (17%)
		leucine-rich repeat	148..171	CDD:275380	7/22 (32%)
		leucine-rich repeat	172..192	CDD:275380	7/19 (37%)
		LRR_RI	<187..400	CDD:238064	53/213 (25%)
		LRR_8	192..251	CDD:290566	13/58 (22%)
		leucine-rich repeat	193..216	CDD:275380	3/22 (14%)
		leucine-rich repeat	217..240	CDD:275380	8/22 (36%)
		leucine-rich repeat	241..267	CDD:275380	4/25 (16%)
		leucine-rich repeat	268..291	CDD:275380	8/22 (36%)
		LRR_8	290..350	CDD:290566	20/60 (33%)
		leucine-rich repeat	292..315	CDD:275380	9/22 (41%)
		leucine-rich repeat	316..339	CDD:275380	5/23 (22%)
		LRR_8	340..400	CDD:290566	13/59 (22%)
		leucine-rich repeat	340..365	CDD:275380	5/24 (21%)
		leucine-rich repeat	366..389	CDD:275380	5/22 (23%)
		leucine-rich repeat	390..413	CDD:275380	7/22 (32%)
		LRR_8	391..448	CDD:290566	11/56 (20%)
		leucine-rich repeat	414..437	CDD:275380	4/22 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472908
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840