Protein Alignment caps and Con

DIOPT Version :10

• Sequence 1: NP_001303391.1
• Gene: caps / 39493
• FlyBaseID: FBgn0023095
• Length: 811
• Species: Drosophila melanogaster
• Sequence 2: NP_523930.3
• Gene: Con / 38590
• FlyBaseID: FBgn0005775
• Length: 691
• Species: Drosophila melanogaster
• Alignment Length: 738
• Identity: 150/738 - (20%)
• Similarity: 240/738 - (32%)
• Gaps: 298/738 - (40%)

  Fly    63 LDVLPIALNPAIQRL---VIKNNKLKTIDSSMQFYAQLTFLD---LSFNDMLTIPERSFAYHAKL 121
            ||.:|..:...::.|   ||:.::::.:.|  ..:|.|.||:   |:.|.::.:.:.:||.|.:|
  Fly   171 LDYIPTMIIEPLKNLSSIVIEYSQVEIVKS--YAFANLPFLERIILNNNHIMALDQDAFANHIRL 233

  Fly   122 QELHLDHNKIGQVSNKTFLGLSTISVLNLRGNLIAELEYRTFSPMVKLAELNLGQNRISHIDPHA 186
            :||:|:||:|.::....|..|.....|.|..|.|:.|....|:.|.:|..|||..|:|:.:....
  Fly   234 RELNLEHNQIFEMDRYAFRNLPLCERLFLNNNNISTLHEGLFADMARLTFLNLAHNQINVLTSEI 298

  Fly   187 LDGLDNLRVLYLDDNTLTTVPGELTFQALHSLAELYLGTNSFMTIPGGAFQDLKGLTRLDLRGAG 251
            ..||.||.||.|..|.|..: |:..|..|.||:|
  Fly   299 FRGLGNLNVLKLTRNNLNFI-GDTVFAELWSLSE------------------------------- 331

  Fly   252 LHNISGDALKGLVSLRFLDLSDNRLPAIPTAAFQRLGRLEQLNIGQNDFEVISSGAFSGLRELRH 316
                             |:|.|||:..|...|...|..|:.||:..|
  Fly   332 -----------------LELDDNRIERISERALDGLNTLKTLNLRNN------------------ 361

  Fly   317 LELTGAQRLRRVESGAFSGNTNLEHLNLSSNKQLNELSSIALGGLPHLSTVVLKANQLSSLDEGL 381
                   .|:::::|...|...|..:|:.:||         |..|...:...:..|.::|..|.|
  Fly   362 -------LLKKIDNGLLRGTPALLSINVQANK---------LETLTFYTFQPIMDNLVNSTSELL 410

  Fly   382 VPWADLQTLDLSENPFECDCRLLWL-------RHLLVSRNASGQYAPVICAYPTALRDLPLAHLA 439
            |          |:|.|.|||||.|:       |||.:..:....:.        .|::..|:|..
  Fly   411 V----------SDNKFICDCRLQWIFELKNRTRHLQLRDSLEDLHC--------TLQEPKLSHFV 457

  Fly   440 EPLLGCAHGAASKQAIIGILVVACAALITTLALVLYTCRHRIREMLKGHSALGRKEREYQKTFSD 504
            :|:         ...|:.:|.:
  Fly   458 DPV---------PPTILDVLNI------------------------------------------- 470

  Fly   505 EEYMSRPPPGGGGVHPAAGGYPYIAGNSRMIPVTELXLEAPPPPQLRGRGGGGGASTASGAVQQL 569
                              ||:..|..||..:                   ||.|.|....:...|
  Fly   471 ------------------GGFTAIGSNSASM-------------------GGVGNSVVGSSYSGL 498

  Fly   570 QVPSAVDQASNSFAQLSHIHYMTNNGQQQQAQQQQST--SKMHH--------SQQDMRLLA---- 620
                .:|.:.......|.   ....||:|.|...::.  |||..        .::|:..:|
  Fly   499 ----TMDDSRKHLGSRSR---QALRGQRQFASSAENVVESKMRRRRKRQEEVKEKDLAAVAPAHK 556

  Fly   621 -------CNGGKPLN-----ATSLPRHR-------PPVVQESTL-----SHYSQPLANGIRLTQD 661
                   .|||..|.     ..:|..|:       .|||..:.:     ||.:...|..|..|::
  Fly   557 RYDYYDDNNGGMSLGHGLDLDDNLSLHKQGFYGAGSPVVGHNDVDVLMTSHSASGDALDILTTKN 621

  Fly   662 HFNHNQNQSHNQHYGGVYAK---------PC-DAMSEPGYIHNNSHYSLPLDHDLPPSPTPTPPP 716
                           .:|.|         || |.:|:|        ..|||..||
  Fly   622 ---------------AIYIKLFLLKPEMLPCHDELSDP--------TELPLSRDL---------- 653

  Fly   717 PALPLRNGVGMALIHGNTTGRRS 739
              :.:|:.||..:   :|.|..|
  Fly   654 --MDVRSNVGQDM---STAGANS 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	4/23 (17%)
		LRR_8	96..155	CDD:404697	20/61 (33%)
		leucine-rich repeat	97..120	CDD:275380	8/25 (32%)
		leucine-rich repeat	121..144	CDD:275380	9/22 (41%)
		LRR	135..>398	CDD:443914	58/262 (22%)
		leucine-rich repeat	145..168	CDD:275380	7/22 (32%)
		leucine-rich repeat	169..192	CDD:275380	8/22 (36%)
		leucine-rich repeat	193..217	CDD:275380	9/23 (39%)
		leucine-rich repeat	218..241	CDD:275380	2/22 (9%)
		leucine-rich repeat	242..265	CDD:275380	0/22 (0%)
		leucine-rich repeat	266..289	CDD:275380	8/22 (36%)
		leucine-rich repeat	290..313	CDD:275380	4/22 (18%)
		leucine-rich repeat	314..335	CDD:275380	2/20 (10%)
		leucine-rich repeat	339..363	CDD:275380	6/23 (26%)
		LRRCT	395..445	CDD:214507	15/56 (27%)
Con	NP_523930.3	LRR	<157..459	CDD:443914	94/390 (24%)
		leucine-rich repeat	185..208	CDD:275380	6/24 (25%)
		leucine-rich repeat	209..232	CDD:275380	6/22 (27%)
		leucine-rich repeat	233..256	CDD:275380	9/22 (41%)
		leucine-rich repeat	257..280	CDD:275380	7/22 (32%)
		leucine-rich repeat	281..304	CDD:275380	8/22 (36%)
		leucine-rich repeat	305..328	CDD:275380	9/23 (39%)
		leucine-rich repeat	329..352	CDD:275380	10/70 (14%)
		leucine-rich repeat	353..376	CDD:275380	7/47 (15%)