Protein Alignment caps and Lrrc24

DIOPT Version :10

• Sequence 1: NP_001303391.1
• Gene: caps / 39493
• FlyBaseID: FBgn0023095
• Length: 811
• Species: Drosophila melanogaster
• Sequence 2: NP_001129368.1
• Gene: Lrrc24 / 362945
• RGDID: 1308720
• Length: 521
• Species: Rattus norvegicus
• Alignment Length: 758
• Identity: 164/758 - (21%)
• Similarity: 227/758 - (29%)
• Gaps: 316/758 - (41%)

  Fly    25 LCLCLVLATLPVALGL----ANCPNGCECDDDTLMVNCGEGTLDVLPIALNPAIQRLVIKNNKLK 85
            |.|.|.|..||:..||    ..||..|.|...|  |.||...|.|:|..:.|..|.|.:::|.
  Rat     9 LLLLLGLLLLPLLPGLPPRATGCPAACRCYSAT--VECGALRLRVVPPGIPPGTQTLFLQDNS-- 69

  Fly    86 TIDSSMQFYAQLTFLDLSFNDMLTIPERSFAYHAKLQELHLDHNKIGQVSNKTFLGLSTISVLNL 150
                                                                             
  Rat    70 ----------------------------------------------------------------- 69

  Fly   151 RGNLIAELEYRTFSPMVKLAELNLGQNRISHIDPHALDGLDNLRVLYLDDNTLTTVPGELTFQAL 215
                                        |:|::..||..|..||.|||.:|||         :||
  Rat    70 ----------------------------IAHLEQGALAPLAALRHLYLHNNTL---------RAL 97

  Fly   216 HSLAELYLGTNSFMTIPGGAFQDLKGLTRLDLRGAGLHNISGDALKGLVSLRFLDLSDNRLPAIP 280
            .|                |||:....|..|.|.|..|..:.|.|..|||.||.|.|:.|:|..:.
  Rat    98 ES----------------GAFRAQPRLLELALTGNRLRGLRGGAFVGLVQLRVLYLAGNQLAKLL 146

  Fly   281 TAAFQRLGRLEQLNIGQNDFEVISSGAFSGLRELRHLELTGAQRLRRVESGAFSGNTNLEHLNLS 345
            ...|..|.||::|::.:|..|::...|.:||..|..|:|
  Rat   147 DFTFLHLPRLQELHLQENSIELLEDQALAGLSSLALLDL-------------------------- 185

  Fly   346 SNKQLNELSSIALGGLPHLSTVVLKANQLSSLDEGLVPWADLQTLDLSENPFECDCRLLWL---- 406
            |..||..:|.                       |.|.|.:.||.|.|:|||:.|||.|.||
  Rat   186 SRNQLGTISK-----------------------EALQPLSSLQVLRLTENPWRCDCALHWLGSWI 227

  Fly   407 ----RHLLVSRNASGQYAPVICAYPTALRDLPLAHLAEPLLGCAHGAASKQ-----AIIG-ILVV 461
                |.||.||:..     :.||.|..|....|..::...|.|...:.:.:     |.:| .|.|
  Rat   228 KEGGRRLLSSRDKK-----ITCAEPPRLALQSLLEVSGGSLICIPPSVNAEPPELTANLGEDLQV 287

  Fly   462 ACAALITTLALVLYTCRHRIREMLKGHSALGRKEREYQKTFSDEEYMSRPPPGGGGVHPAAGGYP 526
            ||.|......||::      |:||:...  |:.:.:.|..              ||. |..||:.
  Rat   288 ACQASGYPQPLVVW------RKMLQPRD--GKPQAQVQLE--------------GGA-PGLGGHA 329

  Fly   527 YIAGNSRMIPVTELXLEAPPPPQLRGRGGGGGASTASGAVQQLQVPSAVDQASNSFAQLSHIHYM 591
            .....|.|:.:|.:.|......:......||.|...                         .|.:
  Rat   330 TRDTGSGMLFLTNITLAHAGKYECEATNAGGKARVL-------------------------FHLL 369

  Fly   592 TNNGQQQQAQ----QQQSTSKMHHSQQD---------------------MRLLACNGGKPLNATS 631
            .|..:||..|    |..:|..:....|.                     :.|||      |.|..
  Rat   370 VNASRQQSQQLPAPQAPATRPVGQEPQHEGGSMAFRALGLATQTAITAAIALLA------LTALL 428

  Fly   632 LP---------RHRPPVVQESTLSHYSQPLANGIRLTQDHFNHNQNQSHNQHYGGVYAKPCD--A 685
            |.         |.:.||           |...|.....|:.:                .||.  .
  Rat   429 LAAMICRRRRRRKKMPV-----------PSGEGTLFVNDYSD----------------GPCTFAQ 466

  Fly   686 MSEPGYIHNNSHY----SLPLDHDLPPSPTPTPPPPALPLRNG 724
            :.|....|.:..:    |.||..::||...|...||. .||:|
  Rat   467 LEELRDDHGHEMFVIDRSKPLFTEIPPEEPPEHNPPE-GLRSG 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	3/20 (15%)
		LRR_8	96..155	CDD:404697	0/58 (0%)
		leucine-rich repeat	97..120	CDD:275380	0/22 (0%)
		leucine-rich repeat	121..144	CDD:275380	0/22 (0%)
		LRR	135..>398	CDD:443914	62/262 (24%)
		leucine-rich repeat	145..168	CDD:275380	0/22 (0%)
		leucine-rich repeat	169..192	CDD:275380	5/22 (23%)
		leucine-rich repeat	193..217	CDD:275380	10/23 (43%)
		leucine-rich repeat	218..241	CDD:275380	3/22 (14%)
		leucine-rich repeat	242..265	CDD:275380	9/22 (41%)
		leucine-rich repeat	266..289	CDD:275380	8/22 (36%)
		leucine-rich repeat	290..313	CDD:275380	7/22 (32%)
		leucine-rich repeat	314..335	CDD:275380	3/20 (15%)
		leucine-rich repeat	339..363	CDD:275380	4/23 (17%)
		LRRCT	395..445	CDD:214507	19/57 (33%)
Lrrc24	NP_001129368.1	LRR	<61..>213	CDD:443914	63/320 (20%)
		leucine-rich repeat	61..83	CDD:275380	8/116 (7%)
		LRR_8	84..142	CDD:404697	29/82 (35%)
		leucine-rich repeat	84..107	CDD:275380	14/47 (30%)
		leucine-rich repeat	108..131	CDD:275380	9/22 (41%)
		leucine-rich repeat	132..155	CDD:275380	8/22 (36%)
		leucine-rich repeat	156..179	CDD:275380	7/22 (32%)
		leucine-rich repeat	180..203	CDD:275380	10/71 (14%)
		PCC	188..>259	CDD:188093	29/98 (30%)
		Ig_3	267..357	CDD:464046	23/112 (21%)