Protein Alignment caps and chp

DIOPT Version :10

• Sequence 1: NP_001303391.1
• Gene: caps / 39493
• FlyBaseID: FBgn0023095
• Length: 811
• Species: Drosophila melanogaster
• Sequence 2: XP_061510877.1
• Gene: chp / 3289597
• VectorBaseID: AGAMI1_000471
• Length: 1339
• Species: Anopheles gambiae
• Alignment Length: 839
• Identity: 179/839 - (21%)
• Similarity: 277/839 - (33%)
• Gaps: 299/839 - (35%)

  Fly    53 TLMVNCGEGT-LDVLPIAL---NPAIQRLVIKNNKLKTI-DSSMQFYAQLTFLDLSFNDMLTIPE 112
            :|..:.|.|: |.|.||..   ..|::.|.:.||:||.| |:|......|..|:|..|.:..:.:
Mosquito   509 SLRASHGLGSQLVVFPIEAFRKLTALEALDLSNNRLKAIGDTSFHLLRNLVSLELHDNQIDALAK 573

  Fly   113 RSFA--YHAKLQELHLDHNKIGQ------------------------VSNKTFLGLSTISVLNLR 151
            .:|.  .|.||..:.|.:|.|.|                        :..:||:.||.:.::|||
Mosquito   574 GTFQSDIHTKLMMISLGYNNIKQLITHTFVDLEELEALLLGDNRIETIEKRTFMNLSNLKLINLR 638

  Fly   152 GNLIAELEYRTFSPMVKLAELNLGQNRISHIDPHALDGLDNLRVLYLDDN-----TLTTV----- 206
            ||.::::....|..:.:|.:|:|..|.::..|...||.:.:|.:|.:|.:     ||.||
Mosquito   639 GNRLSKIADEAFQNLPELEKLDLAYNSLTAFDFMCLDQVGSLTLLEVDVSNNKIKTLGTVENATD 703

  Fly   207 -----------PGELTFQALH--------------------------SLAELYLGTNSFMTIPGG 234
                       |.:.....:|                          ||.:|.|..|...|:...
Mosquito   704 NGGHREQQQLQPQQPQQPTIHSNIRALDFSNNNISRIIPGYFRPTELSLMKLVLRQNQLTTVARE 768

  Fly   235 AFQDLKGLTRLDLRGAGLHNISGDALKGLVSLRFLDLSDNRLPAIPTAAFQRLGR---------- 289
            .|.::..|:.|||....:..:..|||:....|:.|.||.|.|..:|...|:.:..
Mosquito   769 LFGNMPHLSWLDLSDNEIVELEYDALRSTRKLQVLKLSHNLLTEVPAELFRNVHNLRVLELAHNS 833

  Fly   290 -------------LEQLNIGQNDFEVISSGAFSGLRELRHLEL------TGA------------- 322
                         ||:|::..|....|...|.|.:..|...||      .||
Mosquito   834 LKYLPDSLLLSEGLERLDVSHNQLTKIPVTALSNMAALSLCELDLSHNHIGAIHSIDLSNKFRSL 898

  Fly   323 -------QRLRRVESGAFSGNTNLEHLNLSSNKQLN----------------ELSSIALGGLPHL 364
                   .||.|:|..||:....|..||||.|.:|.                :|::::|..:|.|
Mosquito   899 SWLDLSHNRLVRLEDAAFATLPRLSVLNLSHNDELEVMGKAFVGLENSLIELQLANVSLSSVPEL 963

  Fly   365 STVVLKANQLSSLDEGLVP------WADLQTLDLSENPFECDCRLLWLRHLLVSRNASGQYAPVI 423
            |...|:..::|..|...:|      ...|:.||||||.                          :
Mosquito   964 SNPSLRTLKISHNDLPTIPPELAANMTSLRELDLSEND--------------------------L 1002

  Fly   424 CAYPTALRDLP----LAHLAEPLLGCAH----GAASKQAIIGILVVACAALITTLALVLYTCRHR 480
            .:.|.....||    |:....|:...::    |||.....:.|..:...::.|.:...|    |.
Mosquito  1003 TSVPLITHSLPNLKRLSLSGNPITTLSNTSLLGAADTLEQLDIANLNLHSIETGVLNKL----HY 1063

  Fly   481 IREMLKGHSALGRKEREYQKTFSDEEYMSRPPPGGGGVHPAAGGY--PYIAGNSRMIPVTELXLE 543
            :|.:                |.|              ..||...:  |.|..|:..:  .:|.:|
Mosquito  1064 LRSL----------------TIS--------------TFPALPNFNIPRILENANNL--RDLWIE 1096

  Fly   544 APPPPQLRGRGGGGGASTASGAVQQLQVPSAVDQASNSFAQLSHIHYMTNNGQQQQAQQQQSTSK 608
            ||.||......||...||:              :||...|
Mosquito  1097 APKPPSATSAMGGPVGSTS--------------KASKPIA------------------------- 1122

  Fly   609 MHHSQQDMRLLACNGGKPLNATSLPRHR----PPVVQEST-----LSHYSQPLANGIRLTQDHFN 664
                              :.||.|.|..    |..:|..|     .|..|..:..|:|....||.
Mosquito  1123 ------------------VAATDLRREMDGVLPRKLQSITFGGVGFSRLSDTVLKGVRSATLHFR 1169

  Fly   665 -HNQNQSHNQHYGGVYAKPCDAMSEPGYIHNNSHYSLPLDHDLPPS-PTP-TPPPPALP 720
             ||.:         :.|.|.:.....|....|...::..|:||..| |.| |....|||
Mosquito  1170 LHNTS---------LVALPGNLFRHMGKPVRNITVTIDEDNDLLQSVPNPNTAHYLALP 1219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	8/21 (38%)
		LRR_8	96..155	CDD:404697	21/84 (25%)
		leucine-rich repeat	97..120	CDD:275380	6/24 (25%)
		leucine-rich repeat	121..144	CDD:275380	8/46 (17%)
		LRR	135..>398	CDD:443914	89/380 (23%)
		leucine-rich repeat	145..168	CDD:275380	6/22 (27%)
		leucine-rich repeat	169..192	CDD:275380	7/22 (32%)
		leucine-rich repeat	193..217	CDD:275380	9/70 (13%)
		leucine-rich repeat	218..241	CDD:275380	6/22 (27%)
		leucine-rich repeat	242..265	CDD:275380	7/22 (32%)
		leucine-rich repeat	266..289	CDD:275380	8/22 (36%)
		leucine-rich repeat	290..313	CDD:275380	7/22 (32%)
		leucine-rich repeat	314..335	CDD:275380	11/46 (24%)
		leucine-rich repeat	339..363	CDD:275380	9/39 (23%)
		LRRCT	395..445	CDD:214507	6/53 (11%)
chp	XP_061510877.1	None