Protein Alignment caps and Cpn2

DIOPT Version :10

• Sequence 1: NP_001303391.1
• Gene: caps / 39493
• FlyBaseID: FBgn0023095
• Length: 811
• Species: Drosophila melanogaster
• Sequence 2: NP_001100555.2
• Gene: Cpn2 / 303861
• RGDID: 1305170
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 511
• Identity: 132/511 - (25%)
• Similarity: 207/511 - (40%)
• Gaps: 70/511 - (13%)

  Fly    11 LAP------HLGQAFSLCLCLCLCLVLATLPVALGLANCPNGCECDDDTLMVNCGEGTLDVLPIA 69
            |||      .:.|...||....|.||..|.|       ||.||:|.|..:.  |.:..|..:|:.
  Rat    14 LAPPAQPLTKMFQGAWLCWASLLLLVRVTQP-------CPVGCDCFDRKIF--CSDEQLAAIPLD 69

  Fly    70 L------------------------NPAIQRLVIKNNKLKTID-SSMQFYAQLTFLDLSFNDMLT 109
            :                        :|.:.::|..|.::..:: .:.....:|..|:::.:....
  Rat    70 IPSHVTDIVFVETSFTTVGTRAFSGSPNLTKVVFLNTRVHHLEPDAFGGLPRLEDLEVTGSPFSN 134

  Fly   110 IPERSFAYHAKLQELHLDHNKIGQVSNKTFLGLSTISVLNLRGNLIAELEYRTFSPMVKLAELNL 174
            :....|:..:.|.:|.||.|::..:....|..:.|:..|.|:||.:..|..|.|..:..|..|||
  Rat   135 LSANIFSNLSSLGKLTLDFNRLAALPEDLFHHMDTLESLQLQGNQLQTLPGRLFQSLRYLRTLNL 199

  Fly   175 GQNRISHIDPHALDGLDNLRVLYLDDNTLTTVPGELTFQALHSLAELYLGTNSFMTIPGGAFQDL 239
            .||.::.:.......|.:|::|.|.||....:| |.....|.||.||:|.:|:...:....|..|
  Rat   200 AQNLLTQLPKGMFQSLSSLQILKLSDNMFARLP-EGVLSNLGSLQELFLDSNAITELSPHLFSHL 263

  Fly   240 KGLTRLDLRGAGLHNISGDALKGLVSLRFLDLSDNRLPAIPTAAFQRLGRLEQLNIGQNDFEVIS 304
            ..|.:|.|:...:..:...|...|.:|.||:|.||.|..:|...|.....|..|::..|..|.:.
  Rat   264 LSLEKLWLQHNAISLLPVSAFSSLRNLTFLNLKDNALRTLPAGLFTHNPGLLHLSLSYNQLETVP 328

  Fly   305 SGAFSGLRELRHLELTGAQRLRRVESGAFSGNTNLEHLNLSSNKQLNELSSIALGGLPHLSTVVL 369
            .|:|:.||:|..|.|: ...:..:....|.....|..|:|.|| .|..|.......|..|..:.|
  Rat   329 EGSFANLRKLASLTLS-HNAITHLPENVFRNLEQLVKLSLDSN-NLTVLHPTLFHNLSKLQLLDL 391

  Fly   370 KANQLSSLDEGLVPW-ADLQTLDLSENPFECDCRLLWLRHLLVSRNASGQYAPVICAYPTALRDL 433
            ..|||:.|..|:... .||..|.|..||::|||||.:|...|...|.........||.|..|:..
  Rat   392 SRNQLTMLPGGIFDTNYDLFNLALLGNPWQCDCRLSYLTSWLRLYNDRIFNTHTFCAGPAYLKGQ 456

  Fly   434 PLAHLAEPLLGCAHG----------------------AASKQAII----GILVVAC 463
            .:.:|.:..|.|...                      ||.:|.|.    |.:::||
  Rat   457 LVPNLKQEQLVCPGNPGQLGLDDREPAGSWDLAVEGRAAHRQCIYGNPEGTVLLAC 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	2/21 (10%)
		LRR_8	96..155	CDD:404697	14/58 (24%)
		leucine-rich repeat	97..120	CDD:275380	3/22 (14%)
		leucine-rich repeat	121..144	CDD:275380	6/22 (27%)
		LRR	135..>398	CDD:443914	79/263 (30%)
		leucine-rich repeat	145..168	CDD:275380	7/22 (32%)
		leucine-rich repeat	169..192	CDD:275380	7/22 (32%)
		leucine-rich repeat	193..217	CDD:275380	8/23 (35%)
		leucine-rich repeat	218..241	CDD:275380	7/22 (32%)
		leucine-rich repeat	242..265	CDD:275380	5/22 (23%)
		leucine-rich repeat	266..289	CDD:275380	9/22 (41%)
		leucine-rich repeat	290..313	CDD:275380	7/22 (32%)
		leucine-rich repeat	314..335	CDD:275380	4/20 (20%)
		leucine-rich repeat	339..363	CDD:275380	8/23 (35%)
		LRRCT	395..445	CDD:214507	16/49 (33%)
Cpn2	NP_001100555.2	LRRNT	44..75	CDD:214470	10/39 (26%)
		leucine-rich repeat	77..97	CDD:275380	0/19 (0%)
		LRR	118..418	CDD:443914	85/302 (28%)
		leucine-rich repeat	122..145	CDD:275380	3/22 (14%)
		leucine-rich repeat	146..169	CDD:275380	6/22 (27%)
		leucine-rich repeat	170..193	CDD:275380	7/22 (32%)
		leucine-rich repeat	194..217	CDD:275380	7/22 (32%)
		leucine-rich repeat	218..241	CDD:275380	8/23 (35%)
		leucine-rich repeat	242..265	CDD:275380	7/22 (32%)
		leucine-rich repeat	266..289	CDD:275380	5/22 (23%)
		leucine-rich repeat	290..313	CDD:275380	9/22 (41%)
		leucine-rich repeat	314..337	CDD:275380	7/22 (32%)
		leucine-rich repeat	338..361	CDD:275380	4/23 (17%)
		leucine-rich repeat	362..383	CDD:275380	7/21 (33%)
		leucine-rich repeat	386..405	CDD:275380	7/18 (39%)
		PCC	390..>499	CDD:188093	29/108 (27%)