DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment caps and TSKU

DIOPT Version :9

Sequence 1:NP_001303391.1 Gene:caps / 39493 FlyBaseID:FBgn0023095 Length:811 Species:Drosophila melanogaster
Sequence 2:NP_001305406.1 Gene:TSKU / 25987 HGNCID:28850 Length:367 Species:Homo sapiens


Alignment Length:318 Identity:87/318 - (27%)
Similarity:135/318 - (42%) Gaps:58/318 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 LVLATLPVALGLANCPNGCECDDDTL---------MVNCGEGTLDVLPIALNPAIQRLVIKNNKL 84
            |:|..:..|.....|..||:|:.:|.         .|:|......::|:.:......|.:.:|:|
Human    20 LLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNRL 84

  Fly    85 KTIDSSM---QFYAQLTFLDLSFNDMLTIPERSFAYHAKLQELHLDHNKIGQVSNKTFLGLSTIS 146
            :.::.|:   ..|..|..||||.|.:.:|...:|:....|:.|.|.||.:..:..::|.. |.:|
Human    85 EMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTS-SPLS 148

  Fly   147 VLNLRGNLIAELEYRTFS-----------------------------PMVKLAELNLGQNRISHI 182
            .:||..|.:.|:....|:                             |...:..|||..||:   
Human   149 DVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRL--- 210

  Fly   183 DPHALDGLDN--LRVLYLDDNTLTTV-PGELTFQALHSLAELYLGTNSFMTIP---GGAFQDLKG 241
              ||:..|.:  ||.|.||.|.|..: ||  .|..|..|..|.|.  |...:|   ...|::|.|
Human   211 --HAVPNLRDLPLRYLSLDGNPLAVIGPG--AFAGLGGLTHLSLA--SLQRLPELAPSGFRELPG 269

  Fly   242 LTRLDLRGAGLHNISG-DALKGLVSLRFLDLSDNRLPAIPTAAFQRLGRLEQLNIGQN 298
            |..|||.|....|.:| :...||.||:.||||...|..:|.|....|..|:.:::||:
Human   270 LQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSVGQD 327

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
capsNP_001303391.1 leucine-rich repeat 75..96 CDD:275380 5/23 (22%)
LRR_8 96..155 CDD:290566 19/58 (33%)
leucine-rich repeat 97..120 CDD:275380 8/22 (36%)
leucine-rich repeat 121..144 CDD:275380 6/22 (27%)
LRR_8 143..201 CDD:290566 21/88 (24%)
leucine-rich repeat 145..168 CDD:275380 7/51 (14%)
LRR_RI 147..397 CDD:238064 55/188 (29%)
leucine-rich repeat 169..192 CDD:275380 8/22 (36%)
leucine-rich repeat 193..217 CDD:275380 11/24 (46%)
LRR_8 217..276 CDD:290566 23/62 (37%)
leucine-rich repeat 218..241 CDD:275380 7/25 (28%)
leucine-rich repeat 242..265 CDD:275380 9/23 (39%)
LRR_8 265..321 CDD:290566 13/34 (38%)
leucine-rich repeat 266..289 CDD:275380 9/22 (41%)
leucine-rich repeat 290..313 CDD:275380 3/9 (33%)
LRR_8 312..374 CDD:290566
leucine-rich repeat 314..335 CDD:275380
leucine-rich repeat 339..363 CDD:275380
LRRCT 395..445 CDD:214507
TSKUNP_001305406.1 LRR_RI 52..305 CDD:238064 72/262 (27%)
leucine-rich repeat 76..99 CDD:275380 5/22 (23%)
leucine-rich repeat 100..123 CDD:275380 8/22 (36%)
LRR_8 103..157 CDD:290566 18/54 (33%)
leucine-rich repeat 124..145 CDD:275380 6/21 (29%)
leucine-rich repeat 147..170 CDD:275380 6/22 (27%)
leucine-rich repeat 171..197 CDD:275380 0/25 (0%)
leucine-rich repeat 200..219 CDD:275380 8/23 (35%)
LRR_8 221..279 CDD:290566 24/61 (39%)
leucine-rich repeat 221..244 CDD:275380 11/24 (46%)
leucine-rich repeat 245..269 CDD:275380 7/25 (28%)
LRR_8 268..321 CDD:290566 21/52 (40%)
leucine-rich repeat 270..294 CDD:275380 9/23 (39%)
leucine-rich repeat 295..316 CDD:275380 8/20 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

Return to query results.
Submit another query.