Protein Alignment caps and Nrros

DIOPT Version :10

• Sequence 1: NP_001303391.1
• Gene: caps / 39493
• FlyBaseID: FBgn0023095
• Length: 811
• Species: Drosophila melanogaster
• Sequence 2: NP_666181.3
• Gene: Nrros / 224109
• MGIID: 2445095
• Length: 693
• Species: Mus musculus
• Alignment Length: 702
• Identity: 149/702 - (21%)
• Similarity: 235/702 - (33%)
• Gaps: 259/702 - (36%)

  Fly    21 LCLCLCLCLVLATLPVALGLANCPN--GCECDDDTLMVNCGEGTLDVLPIALNPAIQRLVIKNNK 83
            |.|||....::.......|.|...:  ||:..|.  :.:|....|..:|.:|.|..:.|::..|.
Mouse     6 LWLCLGFHFLIVEWRSGPGTATAASQGGCKVVDG--VADCRGLNLASVPSSLPPHSRMLILDANP 68

  Fly    84 LKTI-DSSMQFYAQLTFLDLSFNDMLTIPERSFAYHAKLQELHLDHNKIGQ------VSNKTFLG 141
            ||.: :.|:|.|.:|..|.|....:..|...:|.....|:.|.|..|::.:      .:..|.||
Mouse    69 LKDLWNHSLQAYPRLENLSLHSCHLDRISHYAFREQGHLRNLVLADNRLSENYKESAAALHTLLG 133

  Fly   142 ----------------------LSTISVLNLRGNLIAELEYRTFSPMVKLAELNLGQNRISHIDP 184
                                  ||::.|::|..|.:..|:...|..:..|.||:|.:|.|..|:.
Mouse   134 LRRLDLSGNSLTEDMAALMLQNLSSLEVVSLARNTLMRLDDSIFEGLEHLVELDLQRNYIFEIEG 198

  Fly   185 HALDGLDNLR------------------------------------------------------- 194
            .|.|||..||
Mouse   199 GAFDGLTELRRLNLAYNNLPCIVDFSLTQLRFLNVSYNILEWFLAAREEVAFELEILDLSHNQLL 263

  Fly   195 ------------VLYLDDNTL--------TTVPGELTFQ-----------------------ALH 216
                        .|.|.||.:        |:.|.|:..|                       .|.
Mouse   264 FFPLLPQCGKLHTLLLQDNNMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVNLWEEFSSSDLS 328

  Fly   217 SLAELYLGTNSFMTIPGGAFQD-------------LK-----------GLTRLDL---RGAGLHN 254
            :|..|.:..|.|..:|.|..:.             ||           .||.|||   :.|.||.
Mouse   329 ALRFLDMSQNQFRHLPDGFLKKTPSLSHLNLNQNCLKMLHIREHEPPGALTELDLSHNQLAELHL 393

  Fly   255 ISGDALKG-LVSLRFLDLSDNRLPAIPTAAFQRLGRLEQLNIGQNDFEVI------------SSG 306
            ..|  |.| |.:||..:||.|:|..:||..|.....:..:::..|...:.            |..
Mouse   394 APG--LTGSLRNLRVFNLSSNQLLGVPTGLFDNASSITTIDMSHNQISLCPQMVPVDWEGPPSCV 456

  Fly   307 AFSGLRELRHLELTGAQRLRRVESGAFSGNTNLEHLNLSSN-----------------KQLNELS 354
            .|..:..||.|.|.|. .|:.::...|.| |:|.||:||||                 .|:..|.
Mouse   457 DFRNMGSLRSLSLDGC-GLKALQDCPFQG-TSLTHLDLSSNWGVLNGSISPLWAVAPTLQVLSLR 519

  Fly   355 SIALG-------------------------------GLPHLSTVVLKANQLSSLDEGLV---PWA 385
            .:.||                               |...|.|:.|:.|.|::|.:.:|   |..
Mouse   520 DVGLGSGAAEMDFSAFGNLRALDLSGNSLTSFPKFKGSLALRTLDLRRNSLTALPQRVVSEQPLR 584

  Fly   386 DLQTLDLSENPFECDCRLL-W---LRHL-------LVSRNASGQYAPVICAYPTALRDLPLAHLA 439
            .|||:.||:||::| |.:. |   .:|.       :|:.|.|.:...|:        :||
Mouse   585 GLQTIYLSQNPYDC-CGVEGWGALQQHFKTVADLSMVTCNLSSKIVRVV--------ELP----- 635

  Fly   440 EPLLGCAHGAASKQAIIG-----ILVVACAALITTLALVLYTCRHRIREMLK 486
               .|...|...:|...|     :::.:|..|:....:|..|.:..:.:::|
Mouse   636 ---EGLPQGCKWEQVDTGLFYLVLILPSCLTLLVACTVVFLTFKKPLLQVIK 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	7/21 (33%)
		LRR_8	96..155	CDD:404697	17/86 (20%)
		leucine-rich repeat	97..120	CDD:275380	5/22 (23%)
		leucine-rich repeat	121..144	CDD:275380	8/50 (16%)
		LRR	135..>398	CDD:443914	100/473 (21%)
		leucine-rich repeat	145..168	CDD:275380	5/22 (23%)
		leucine-rich repeat	169..192	CDD:275380	11/22 (50%)
		leucine-rich repeat	193..217	CDD:275380	11/121 (9%)
		leucine-rich repeat	218..241	CDD:275380	8/46 (17%)
		leucine-rich repeat	242..265	CDD:275380	12/26 (46%)
		leucine-rich repeat	266..289	CDD:275380	9/22 (41%)
		leucine-rich repeat	290..313	CDD:275380	3/34 (9%)
		leucine-rich repeat	314..335	CDD:275380	7/20 (35%)
		leucine-rich repeat	339..363	CDD:275380	12/71 (17%)
		LRRCT	395..445	CDD:214507	12/60 (20%)
Nrros	NP_666181.3	LRR 1. /evidence=ECO:0000255	58..79		5/20 (25%)
		leucine-rich repeat	60..82	CDD:275380	7/21 (33%)
		LRR 2. /evidence=ECO:0000255	82..103		5/20 (25%)
		leucine-rich repeat	83..106	CDD:275380	5/22 (23%)
		LRR	<106..414	CDD:443914	61/309 (20%)
		LRR 3. /evidence=ECO:0000255	106..127		4/20 (20%)
		leucine-rich repeat	107..133	CDD:275380	5/25 (20%)
		LRR 4. /evidence=ECO:0000255	133..155		1/21 (5%)
		leucine-rich repeat	134..158	CDD:275380	1/23 (4%)
		LRR 5. /evidence=ECO:0000255	158..179		5/20 (25%)
		leucine-rich repeat	159..182	CDD:275380	5/22 (23%)
		LRR 6. /evidence=ECO:0000255	182..203		8/20 (40%)
		leucine-rich repeat	183..206	CDD:275380	11/22 (50%)
		LRR 7. /evidence=ECO:0000255	206..227		2/20 (10%)
		leucine-rich repeat	207..251	CDD:275380	2/43 (5%)
		LRR 8. /evidence=ECO:0000255	228..239		0/10 (0%)
		leucine-rich repeat	230..249	CDD:275380	0/18 (0%)
		LRR 9. /evidence=ECO:0000255	251..272		0/20 (0%)
		leucine-rich repeat	252..273	CDD:275380	0/20 (0%)
		LRR 10. /evidence=ECO:0000255	273..294		4/20 (20%)
		leucine-rich repeat	274..329	CDD:275380	9/54 (17%)
		LRR	276..>595	CDD:443914	75/322 (23%)
		LRR 11. /evidence=ECO:0000255	329..350		6/20 (30%)
		leucine-rich repeat	330..353	CDD:275380	6/22 (27%)
		LRR 12. /evidence=ECO:0000255	353..374		2/20 (10%)
		leucine-rich repeat	354..377	CDD:275380	2/22 (9%)
		LRR 13. /evidence=ECO:0000255	377..398		9/22 (41%)
		leucine-rich repeat	378..403	CDD:275380	12/26 (46%)
		LRR 14. /evidence=ECO:0000255	403..424		9/20 (45%)
		leucine-rich repeat	404..427	CDD:275380	9/22 (41%)
		LRR 15. /evidence=ECO:0000255	427..448		1/20 (5%)
		leucine-rich repeat	428..463	CDD:275380	3/34 (9%)
		LRR 16. /evidence=ECO:0000255	463..484		7/21 (33%)
		leucine-rich repeat	464..486	CDD:275380	8/23 (35%)
		LRR 17. /evidence=ECO:0000255	486..507		7/20 (35%)
		leucine-rich repeat	487..512	CDD:275380	7/24 (29%)
		LRR 18. /evidence=ECO:0000255	512..533		4/20 (20%)
		leucine-rich repeat	513..537	CDD:275380	4/23 (17%)
		LRR 19. /evidence=ECO:0000255	537..558		1/20 (5%)
		leucine-rich repeat	538..559	CDD:275380	1/20 (5%)
		LRR 20. /evidence=ECO:0000255	559..580		7/20 (35%)
		LRR 21. /evidence=ECO:0000255	585..605		9/20 (45%)