DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment caps and tbce-1

DIOPT Version :9

Sequence 1:	NP_001303391.1	Gene:	caps / 39493	FlyBaseID:	FBgn0023095	Length:	811	Species:	Drosophila melanogaster
Sequence 2:	NP_501395.1	Gene:	tbce-1 / 177624	WormBaseID:	WBGene00019503	Length:	493	Species:	Caenorhabditis elegans

Alignment Length:	417	Identity:	88/417 - (21%)
Similarity:	146/417 - (35%)	Gaps:	146/417 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 KLQELHLDHNKIGQVSNKTFLGLSTISVLNLRGNLIAE-------LEYRTFSPMVKLAELNLGQN 177
            ||..:.||:..:|...:...........|||.|||:.:       |||     ..::.||||.:|
Worm   119 KLINIVLDNRSVGFPPSSDSPQFILCRELNLYGNLLYKWKTVRQILEY-----FPRIQELNLRRN 178

  Fly   178 RI-----------SHIDPHAL----------------DGLDNLRVLYLDDNTLTTVPGELT---- 211
            |:           |..|.|..                :.:|::.:.:...:.:.....:||
Worm   179 RMQCFNEEEDDDESEGDDHVYSDSCKKLVISECNLSENSIDSILLRFPSTSDVVAFGNDLTRFSV 243

  Fly   212 FQALHS-LAELYLGTNSFMTIPG--GAFQDLKGLTRLDLRGAGLHNISGDALKGLVSLRFLDLSD 273
            .:|:.| |..|.|..|.|.|:..  |.|.:   ||:|.:...|:.:::|  ..|  |::|
Worm   244 SEAVSSRLTSLDLEDNPFKTLDSIHGTFPN---LTQLSVANCGITSLNG--FDG--SIKF----- 296

  Fly   274 NRLPAIPTAAFQRLGRLEQLNIGQNDFEVISSGAFSGLRELRHLELTGAQRLRRVESGAFSGNTN 338
                          .:||.|||.:|  .::...:.:.:|.|:.|     :||.
Worm   297 --------------PKLEYLNIKRN--SIVEWKSVNSIRSLKSL-----KRLL------------ 328

  Fly   339 LEHLNLSSNKQLNELSSIALGGLPHLSTVVLKANQLSSLDEGLVPWADLQTLDLSENPFECDCRL 403
            .:...||:.|.::....:    :..|||::                 ||...|:|    |.:.|.
Worm   329 FDCKKLSTEKGVHAYEIV----IAKLSTLI-----------------DLNRFDVS----EVERRS 368

  Fly   404 LWLRHLLVSRNASGQYAPVICAYPTALRD----------LPLAHLAEPLLGCAHGAASKQAIIGI 458
            ..:|.|       .:||        .|.|          |...| .||.|    ..|.|...:..
Worm   369 AEIRFL-------NKYA--------GLNDNEDHQDDIKRLIEIH-GEPTL----DTAKKGLAVVK 413

  Fly   459 LVVACAALITTLALVLYTCRHRIREML 485
            :.:.|...:.|..|.|.....:||:||
Worm   414 IRIECGNRVETRRLPLGMSIQKIRDML 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380
		LRR_8	96..155	CDD:290566	10/34 (29%)
		leucine-rich repeat	97..120	CDD:275380	88/417 (21%)
		leucine-rich repeat	121..144	CDD:275380	4/22 (18%)
		LRR_8	143..201	CDD:290566	19/91 (21%)
		leucine-rich repeat	145..168	CDD:275380	9/29 (31%)
		LRR_RI	147..397	CDD:238064	60/290 (21%)
		leucine-rich repeat	169..192	CDD:275380	9/49 (18%)
		leucine-rich repeat	193..217	CDD:275380	3/27 (11%)
		LRR_8	217..276	CDD:290566	17/61 (28%)
		leucine-rich repeat	218..241	CDD:275380	8/24 (33%)
		leucine-rich repeat	242..265	CDD:275380	6/22 (27%)
		LRR_8	265..321	CDD:290566	11/55 (20%)
		leucine-rich repeat	266..289	CDD:275380	1/22 (5%)
		leucine-rich repeat	290..313	CDD:275380	6/22 (27%)
		LRR_8	312..374	CDD:290566	11/61 (18%)
		leucine-rich repeat	314..335	CDD:275380	4/20 (20%)
		leucine-rich repeat	339..363	CDD:275380	3/23 (13%)
		LRRCT	395..445	CDD:214507	13/59 (22%)
tbce-1	NP_501395.1	CAP_GLY	3..65	CDD:214997
		leucine-rich repeat	145..169	CDD:275380	9/28 (32%)
		leucine-rich repeat	170..205	CDD:275380	9/34 (26%)
		LRR_RI	<204..372	CDD:393385	44/237 (19%)
		leucine-rich repeat	206..233	CDD:275380	1/26 (4%)
		leucine-rich repeat	251..273	CDD:275380	8/21 (38%)
		leucine-rich repeat	274..298	CDD:275380	8/46 (17%)
		leucine-rich repeat	299..323	CDD:275380	8/25 (32%)
		Ubl_TBCE	410..491	CDD:340564	8/31 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000