Protein Alignment caps and lron-11

DIOPT Version :10

• Sequence 1: NP_001303391.1
• Gene: caps / 39493
• FlyBaseID: FBgn0023095
• Length: 811
• Species: Drosophila melanogaster
• Sequence 2: NP_491035.1
• Gene: lron-11 / 171837
• WormBaseID: WBGene00022129
• Length: 542
• Species: Caenorhabditis elegans
• Alignment Length: 568
• Identity: 148/568 - (26%)
• Similarity: 243/568 - (42%)
• Gaps: 87/568 - (15%)

  Fly    30 VLATLPVALGLANCPNGCECDDDTLMVNCGEGTLDVLPIALNPAIQRLVIKNNKLKTIDS-SMQF 93
            ||..|.:..|:.:|.:||:|...|..| |...:|..:||.|:|....|.:.||::..:.: .:..
 Worm     5 VLILLVLVSGVISCQSGCKCPTKTTAV-CKGSSLRSIPILLDPRTTVLDLSNNRISRLSADELSL 68

  Fly    94 YAQLTFLDLSFNDMLTIPERSFAYHAKLQELHLDHNKIGQVSNKTFLGLSTISVLNLRGNLIAEL 158
            |..|..|.|..|.:..:....|:....|:.|.|..|.:..:.|:.|..|..:..|.:..|.: :|
 Worm    69 YPNLEQLILHNNSITHLSADVFSTLPSLRVLDLSSNSLLSLPNEVFSKLKNLKTLIISSNDV-QL 132

  Fly   159 EYRTFSPMVKLAELNLGQNRISHIDPHALDGLDNLRVLYLDDNTLTTVPGELTFQALHSLAELYL 223
            ....|:.:.:|..|::..||:|.:.|..|..|..||.|.|..|.|.::|..: ...|..|..|.|
 Worm   133 GPECFAGLSQLQTLSIADNRLSFLPPSVLKPLSGLRNLDLSANKLLSMPASV-MNNLGGLETLKL 196

  Fly   224 GTNSFMTIPGGAFQDLKGLTRLDLRGAGLHNISGD----ALKGLVSLRFLDLSDNRLPAIPTAAF 284
            ..|...::..|.|...|.|..||:.    .|:.||    ||.||..|..|:|::|:|..:|...:
 Worm   197 KQNLLSSLETGMFLSQKELKHLDVS----ENLIGDIEEGALYGLEKLETLNLTNNQLVRLPGNTW 257

  Fly   285 QRLGRLEQLNIGQNDFEVISSGAFSGLRELRHLELTGAQRLRRVESGAFSGNTNLEHLNLSSNKQ 349
            . |..|:.|::..|.|..:.:.:|.||..|::|.::.::.|:.::...|...::|..|::||: .
 Worm   258 S-LPALKTLDLSSNLFVSLETASFDGLPALQYLNISHSRNLKTIQMATFVQLSSLHWLSISSS-A 320

  Fly   350 LNELSSIALGGLPHLSTVVLKANQLSSLDEGLVPWADLQTLDLSENPFECDCRLLWLRHLLVSRN 414
            |..:...|...:|.||.:.|..|:|..:..|::.|.:::.|.|:.|.:.|.|.|. :.:|....:
 Worm   321 LTHIHPSAFNPIPPLSHLDLSNNELRYVAPGMLQWPNIRNLHLANNDWHCSCDLR-VSNLNPRDD 384

  Fly   415 ASGQYAPVICAYPTALRDLPLAHLAE-PLLGCAHGAASKQAIIGILVVACAAL-ITTLALVL--Y 475
            |.       |:.|..|...|:..|:. .:||            |:|:.....| |..||||:  .
 Worm   385 AK-------CSGPENLAGAPINELSSCSILG------------GLLIPFLLVLFILLLALVILAL 430

  Fly   476 TCRHRIREMLKGHS-------ALGRKEREYQ------KTFSDEE-----YMS--------RPPPG 514
            .|:......||..:       |.....:||.      .|.|.|:     |.|        ||||.
 Worm   431 ACKKSKPVSLKNRAFYNDQLIAALNSHKEYSFDCHSPYTMSSEDSRDSAYESPTSALMPRRPPPS 495

  Fly   515 ------------GGGVHPAA----------GGYPYIAGNSRMIPVTEL 540
                        .|..|.|.          ...||:...|: :|:|.|
 Worm   496 CPPPPRLLTLPRAGPTHVAPPMVPVPNFRNSNDPYLIPKSQ-VPITRL 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	4/21 (19%)
		LRR_8	96..155	CDD:404697	14/58 (24%)
		leucine-rich repeat	97..120	CDD:275380	5/22 (23%)
		leucine-rich repeat	121..144	CDD:275380	7/22 (32%)
		LRR	135..>398	CDD:443914	75/266 (28%)
		leucine-rich repeat	145..168	CDD:275380	4/22 (18%)
		leucine-rich repeat	169..192	CDD:275380	8/22 (36%)
		leucine-rich repeat	193..217	CDD:275380	8/23 (35%)
		leucine-rich repeat	218..241	CDD:275380	6/22 (27%)
		leucine-rich repeat	242..265	CDD:275380	10/26 (38%)
		leucine-rich repeat	266..289	CDD:275380	7/22 (32%)
		leucine-rich repeat	290..313	CDD:275380	7/22 (32%)
		leucine-rich repeat	314..335	CDD:275380	4/20 (20%)
		leucine-rich repeat	339..363	CDD:275380	6/23 (26%)
		LRRCT	395..445	CDD:214507	12/50 (24%)
lron-11	NP_491035.1	LRR	33..368	CDD:443914	93/342 (27%)
		leucine-rich repeat	48..71	CDD:275380	4/22 (18%)
		leucine-rich repeat	72..95	CDD:275380	5/22 (23%)
		leucine-rich repeat	96..119	CDD:275380	7/22 (32%)
		leucine-rich repeat	120..142	CDD:275380	4/22 (18%)
		leucine-rich repeat	143..166	CDD:275380	8/22 (36%)
		leucine-rich repeat	167..190	CDD:275380	8/23 (35%)
		leucine-rich repeat	191..214	CDD:275380	6/22 (27%)
		leucine-rich repeat	215..238	CDD:275380	10/26 (38%)
		leucine-rich repeat	239..261	CDD:275380	7/22 (32%)
		leucine-rich repeat	262..283	CDD:275380	5/20 (25%)
		leucine-rich repeat	286..310	CDD:275380	4/23 (17%)
		leucine-rich repeat	311..334	CDD:275380	6/23 (26%)
		leucine-rich repeat	335..357	CDD:275380	7/21 (33%)