DRSC/TRiP Functional Genomics Resources

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Protein Alignment caps and LRFN5

DIOPT Version :9

Sequence 1:NP_001303391.1 Gene:caps / 39493 FlyBaseID:FBgn0023095 Length:811 Species:Drosophila melanogaster
Sequence 2:NP_001333102.1 Gene:LRFN5 / 145581 HGNCID:20360 Length:719 Species:Homo sapiens


Alignment Length:306 Identity:85/306 - (27%)
Similarity:117/306 - (38%) Gaps:75/306 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   148 LNLRGNLIAELEYRTFSPMVKLAELNLGQNRISHIDPHALDGLDNLRVLYLDDNTLTTVPGELTF 212
            |.|..|.:..::.:.|:.|..|.:|.|.:|.||.|.|||...|.|||.|:|:.|.||.:..:: |
Human    56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDM-F 119

  Fly   213 QALHSLAELYLGTNSFMTIPGGAFQDLKGLTRLDLRGAGLHNISGDALKGLVSLRFLDLSDNRLP 277
            ..|.:|..|.|..|....|...||.|:..|..|||....|..|..||::.:|||..|.|..|.:.
Human   120 SGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMID 184

  Fly   278 AIPTAAFQRLGRLEQLNIGQNDFEVISSGAFSGLRELRHLELTGAQRLRRVESGAFSGNTNLEHL 342
            .||...|..|.::.:|::..|..:.:.....          ...||.|  ..||..|.:|     
Human   185 NIPKGTFSHLHKMTRLDVTSNKLQKLPPDPL----------FQRAQVL--ATSGIISPST----- 232

  Fly   343 NLSSNKQLNELSSIALGGLPHLSTVVLKANQLSSLDEGLVPWADLQTLDLSENPFECDCRLLWLR 407
                       .:::.||                                  ||..|:|.|||||
Human   233 -----------FALSFGG----------------------------------NPLHCNCELLWLR 252

  Fly   408 HLLVSRNASGQYAPVICAYPTALR-----DLPLAH-LAEPLLGCAH 447
            .|  ||....:    .||.|..|.     .:|... |.||.|...|
Human   253 RL--SREDDLE----TCASPPLLTGRYFWSIPEEEFLCEPPLITRH 292

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
capsNP_001303391.1 leucine-rich repeat 75..96 CDD:275380
LRR_8 96..155 CDD:290566 3/6 (50%)
leucine-rich repeat 97..120 CDD:275380
leucine-rich repeat 121..144 CDD:275380
LRR_8 143..201 CDD:290566 21/52 (40%)
leucine-rich repeat 145..168 CDD:275380 5/19 (26%)
LRR_RI 147..397 CDD:238064 64/248 (26%)
leucine-rich repeat 169..192 CDD:275380 11/22 (50%)
leucine-rich repeat 193..217 CDD:275380 9/23 (39%)
LRR_8 217..276 CDD:290566 22/58 (38%)
leucine-rich repeat 218..241 CDD:275380 8/22 (36%)
leucine-rich repeat 242..265 CDD:275380 8/22 (36%)
LRR_8 265..321 CDD:290566 11/55 (20%)
leucine-rich repeat 266..289 CDD:275380 8/22 (36%)
leucine-rich repeat 290..313 CDD:275380 2/22 (9%)
LRR_8 312..374 CDD:290566 9/61 (15%)
leucine-rich repeat 314..335 CDD:275380 5/20 (25%)
leucine-rich repeat 339..363 CDD:275380 2/23 (9%)
LRRCT 395..445 CDD:214507 21/55 (38%)
LRFN5NP_001333102.1 LRR 1 52..73 4/16 (25%)
LRR 2 76..97 10/20 (50%)
LRR 3 100..121 9/21 (43%)
LRR 4 124..145 7/20 (35%)
LRR 5 148..169 8/20 (40%)
LRR 6 172..193 8/20 (40%)
LRR 7 196..217 2/30 (7%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 385..414
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 615..694
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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