DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment caps and LOC100535105

DIOPT Version :9

Sequence 1:	NP_001303391.1	Gene:	caps / 39493	FlyBaseID:	FBgn0023095	Length:	811	Species:	Drosophila melanogaster
Sequence 2:	XP_009298331.1	Gene:	LOC100535105 / 100535105	-ID:	-	Length:	706	Species:	Danio rerio

Alignment Length:	398	Identity:	105/398 - (26%)
Similarity:	174/398 - (43%)	Gaps:	44/398 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LCLCLVLATLPVAL-GLANCPNGCECD-----------DDTLMVNCGEGTLDVLPIALNPAIQRL 77
            |.:.|.:||..:|. ...:||..|.|:           .:...::|.:..|..||..|....|.|
Zfish    10 LLVGLAMATFVIAAEEKISCPKLCVCEIRPWFSPSSVYMEAPTIDCNDLGLFKLPTRLPLDTQVL 74

  Fly    78 VIKNNKLKTIDSSMQFYAQLTFLDLSFNDMLTIPERSFAYHAKLQELHLDHNKIGQVSNKTFLGL 142
            :::.|.:...:..:.:...:|.:|||.|::.:|.:.:.....:|..||::.
Zfish    75 LLQTNNIAKNEHPLDYLTNITEIDLSQNNLSSINDINIGSLPQLLSLHMEE-------------- 125

  Fly   143 STISVLNLRGNLIAELEYRTFSPMVKLAELNLGQNRISHIDPHALDGLDNLRVLYLDDNTLTTVP 207
                      |.|..|...:.|.:..|.||.|..|.||.|.|.|..||.:|..|:|:.|.|..:.
Zfish   126 ----------NWICSLPDNSLSQLTNLQELYLNHNLISLISPEAFRGLQSLLRLHLNSNRLQIIK 180

  Fly   208 GELTFQALHSLAELYLGTNSFMTIPGGAFQDLKGLTRLDLRGAGLHNISGDALKGLVSLRFLDLS 272
            .| .|:.|.:|..|.:|.|..::|....|:.|:.|..|.|....|..|..|:..||.:|..:...
Zfish   181 SE-WFEPLPNLEILMIGENPVLSIQDMNFKPLRNLRSLVLTRMNLSQIPDDSFLGLDNLESISFY 244

  Fly   273 DNRLPAIPTAAFQRLGRLEQLNIGQNDFEVISSGAFSGLRELRHLELTGAQRLRRVESGAFSGNT 337
            ||..|.:|..|.:.|..|:.|::.:|....|..|.|..:..|:.|.:.....|..::|.|.:...
Zfish   245 DNTFPKVPHGALRHLKSLKFLDLNKNPIGRIQRGDFVDMLHLKELGINSMPELVSIDSFALNNLP 309

  Fly   338 NLEHLNLSSNKQLNELSSIALGGLPHLSTVVLKANQLSSLD----EGLVPWADLQTLDLSENPFE 398
            .|..:..::|.:|:.:...|...||.|.|::|..|.||:|.    |.|   .:|:.:.:..||..
Zfish   310 ELTKIEATNNPKLSYIHPNAFYRLPRLETLMLNGNALSALHRITVESL---PNLREVSMHSNPIR 371

  Fly   399 CDCRLLWL 406
            |||.:.|:
Zfish   372 CDCVVRWM 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	3/20 (15%)
		LRR_8	96..155	CDD:290566	10/58 (17%)
		leucine-rich repeat	97..120	CDD:275380	6/22 (27%)
		leucine-rich repeat	121..144	CDD:275380	3/22 (14%)
		LRR_8	143..201	CDD:290566	19/57 (33%)
		leucine-rich repeat	145..168	CDD:275380	4/22 (18%)
		LRR_RI	147..397	CDD:238064	74/253 (29%)
		leucine-rich repeat	169..192	CDD:275380	12/22 (55%)
		leucine-rich repeat	193..217	CDD:275380	8/23 (35%)
		LRR_8	217..276	CDD:290566	18/58 (31%)
		leucine-rich repeat	218..241	CDD:275380	7/22 (32%)
		leucine-rich repeat	242..265	CDD:275380	8/22 (36%)
		LRR_8	265..321	CDD:290566	15/55 (27%)
		leucine-rich repeat	266..289	CDD:275380	7/22 (32%)
		leucine-rich repeat	290..313	CDD:275380	6/22 (27%)
		LRR_8	312..374	CDD:290566	15/61 (25%)
		leucine-rich repeat	314..335	CDD:275380	5/20 (25%)
		leucine-rich repeat	339..363	CDD:275380	5/23 (22%)
		LRRCT	395..445	CDD:214507	6/12 (50%)
LOC100535105	XP_009298331.1	leucine-rich repeat	52..70	CDD:275380	5/17 (29%)
		leucine-rich repeat	71..93	CDD:275380	3/21 (14%)
		LRR_RI	88..>273	CDD:238064	58/209 (28%)
		leucine-rich repeat	95..117	CDD:275380	6/21 (29%)
		LRR_8	116..176	CDD:290566	23/83 (28%)
		leucine-rich repeat	118..141	CDD:275380	7/46 (15%)
		leucine-rich repeat	142..165	CDD:275380	12/22 (55%)
		LRR_8	165..221	CDD:290566	18/56 (32%)
		leucine-rich repeat	166..189	CDD:275380	8/23 (35%)
		leucine-rich repeat	190..213	CDD:275380	7/22 (32%)
		LRR_8	212..272	CDD:290566	18/59 (31%)
		leucine-rich repeat	214..237	CDD:275380	8/22 (36%)
		leucine-rich repeat	238..261	CDD:275380	7/22 (32%)
		leucine-rich repeat	262..285	CDD:275380	6/22 (27%)
		leucine-rich repeat	286..310	CDD:275380	5/23 (22%)
		LRR_8	309..370	CDD:290566	17/63 (27%)
		leucine-rich repeat	311..333	CDD:275380	4/21 (19%)
		leucine-rich repeat	336..357	CDD:275380	8/20 (40%)
		leucine-rich repeat	360..372	CDD:275378	3/11 (27%)
		LRRCT	368..411	CDD:214507	6/12 (50%)
		IG_like	429..513	CDD:214653
		Ig	437..513	CDD:299845
		fn3	518..593	CDD:278470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4248
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6470
orthoMCL	1	0.900	-	-		OOG6_103993
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.860