DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment caps and lrrtm1

DIOPT Version :9

Sequence 1:	NP_001303391.1	Gene:	caps / 39493	FlyBaseID:	FBgn0023095	Length:	811	Species:	Drosophila melanogaster
Sequence 2:	XP_002935525.1	Gene:	lrrtm1 / 100493874	XenbaseID:	XB-GENE-966481	Length:	521	Species:	Xenopus tropicalis

Alignment Length:	404	Identity:	102/404 - (25%)
Similarity:	157/404 - (38%)	Gaps:	96/404 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LCLCLCL--------CLVLATLPV---ALGLAN--CPNGCECDDDTLMVNCGEGTLDVLPIALNP 72
            |.:.|||        .|:|.||.|   .|.|.|  ||..|.|:...|.  |....:..:|..|:.
Frog     4 LLIGLCLNWLLRKPPGLILCTLGVFVKMLPLVNSGCPRLCRCEGRFLY--CESQNVTEIPHNLSG 66

  Fly    73 AIQRLVIKNNKLKTIDSSMQFYAQLTFLDLSFNDMLTIPERSFAYHAKLQELHLDHNKIGQVSNK 137
            .:.                        |.|.:|.:..:.:..|....:|..|:||||.|..|...
Frog    67 VMG------------------------LSLRYNSLSELQDGQFTGLIQLTWLYLDHNHIHTVEGN 107

  Fly   138 TFLGLSTISVLNLRGNLIAELEYRTFSPMVKLAELNLGQNRISHIDPHALDGLDNLRVLYLDDNT 202
            .|..|..:..|.|..|.|..|...||.||                        .|||.:.|.:|.
Frog   108 AFHKLRRVKELTLSSNKITHLANTTFRPM------------------------PNLRSVDLSNNN 148

  Fly   203 LTTVPGELTFQALHSLAELYLGTNSFMTIPGGAFQDLKGLTRLDLRGAGLHNISGDALKGLVSLR 267
            |.::..:| |..|..|..|::..|:...:|...|||.:                        ||:
Frog   149 LQSLEADL-FHGLRKLTTLHMRYNAIKFVPVRIFQDCR------------------------SLK 188

  Fly   268 FLDLSDNRLPAIPTAAFQRLGRLEQLNIGQNDFEVISSGAFSGLRELRHLELTGAQRLRRVESGA 332
            ||||..|:|.::...:|..|.:|.:|::..||...::...|..|..|..|.:...:....|.|..
Frog   189 FLDLGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNLAHFPRLLSLHSLFMRRNKVTIVVNSLD 253

  Fly   333 FSGNTNLEHLNLSSNKQLNELSSIALGGLPHLSTVVLKANQLSSLDEGLV-PWADLQTLDLSENP 396
            |.  ..||.::||.| ::..:.......||||.::.|.:|:|:.:|..:: .|..|.::.|:.|.
Frog   254 FV--WKLEKMDLSGN-EIEYIEPHVFESLPHLESLQLDSNRLTYVDPRILNSWKSLSSITLAGNN 315

  Fly   397 FECD---CRLL-WL 406
            ::|.   |.|. ||
Frog   316 WDCGRNVCALASWL 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	0/20 (0%)
		LRR_8	96..155	CDD:290566	17/58 (29%)
		leucine-rich repeat	97..120	CDD:275380	4/22 (18%)
		leucine-rich repeat	121..144	CDD:275380	10/22 (45%)
		LRR_8	143..201	CDD:290566	13/57 (23%)
		leucine-rich repeat	145..168	CDD:275380	9/22 (41%)
		LRR_RI	147..397	CDD:238064	63/250 (25%)
		leucine-rich repeat	169..192	CDD:275380	0/22 (0%)
		leucine-rich repeat	193..217	CDD:275380	8/23 (35%)
		LRR_8	217..276	CDD:290566	14/58 (24%)
		leucine-rich repeat	218..241	CDD:275380	7/22 (32%)
		leucine-rich repeat	242..265	CDD:275380	0/22 (0%)
		LRR_8	265..321	CDD:290566	18/55 (33%)
		leucine-rich repeat	266..289	CDD:275380	9/22 (41%)
		leucine-rich repeat	290..313	CDD:275380	6/22 (27%)
		LRR_8	312..374	CDD:290566	16/61 (26%)
		leucine-rich repeat	314..335	CDD:275380	5/20 (25%)
		leucine-rich repeat	339..363	CDD:275380	6/23 (26%)
		LRRCT	395..445	CDD:214507	6/16 (38%)
lrrtm1	XP_002935525.1	LRRNT	38..>61	CDD:214470	6/24 (25%)
		LRR	53..>316	CDD:227223	79/338 (23%)
		leucine-rich repeat	70..90	CDD:275380	4/19 (21%)
		leucine-rich repeat	91..114	CDD:275380	10/22 (45%)
		LRR_8	114..173	CDD:338972	21/83 (25%)
		leucine-rich repeat	115..138	CDD:275380	9/46 (20%)
		leucine-rich repeat	139..162	CDD:275380	8/23 (35%)
		leucine-rich repeat	163..186	CDD:275380	7/46 (15%)
		leucine-rich repeat	187..210	CDD:275380	9/22 (41%)
		leucine-rich repeat	211..234	CDD:275380	6/22 (27%)
		leucine-rich repeat	235..257	CDD:275380	5/23 (22%)
		leucine-rich repeat	258..281	CDD:275380	6/23 (26%)
		leucine-rich repeat	282..300	CDD:275380	5/17 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910