Protein Alignment caps and lrrn1l

DIOPT Version :10

• Sequence 1: NP_001303391.1
• Gene: caps / 39493
• FlyBaseID: FBgn0023095
• Length: 811
• Species: Drosophila melanogaster
• Sequence 2: NP_001106456.1
• Gene: lrrn1l / 100127637
• XenbaseID: XB-GENE-492890
• Length: 738
• Species: Xenopus tropicalis
• Alignment Length: 710
• Identity: 169/710 - (23%)
• Similarity: 273/710 - (38%)
• Gaps: 177/710 - (24%)

  Fly    24 CLCLCLVLATLPVALGLANCPNGCECD-----------DDTLMVNCGEGTLDVLPIALNPAIQRL 77
            ||.:.::.:.....||:  ||..|.|:           .:...|:|.:..|..:|..|:..||.|
 Frog    21 CLFVIVLHSVFFSTLGV--CPPQCVCETRPWFTPQSVYHEAKTVDCNDLLLTHIPENLSTDIQVL 83

  Fly    78 VIKNNKLKTIDSSMQFYAQLTFLDLSFNDMLTIPERSFAYHAKLQELHLDHNKIGQVSNKTFLGL 142
            ::::||:..:...:|..:.||.||||.|...:|.:...:..::|..|:|:.|::.::.:.:...|
 Frog    84 LLQSNKISHLTWELQELSNLTELDLSQNHFQSIDDLGVSNLSQLITLYLEENQLRELPDYSLKDL 148

  Fly   143 STISVLNLRGNLIAELEYRTFSPMVKLAELNLGQNRISHIDPHALDGLDNLRVLYLDDNTLTTVP 207
            .::..|.:..|.|:.:..|.||.:.:|..|:|..||:..|||...:.|.||.:|.:.:|.:|
 Frog   149 GSLEELYINHNQISYIGPRAFSGLGRLLRLHLNANRLEIIDPRWFEDLPNLEILMVGENPVT--- 210

  Fly   208 GELTFQALHSLAELYLGTNSFMTIPGGAFQDLKGLTRLDLRGAGLHNISGDALKGLVSLRFLDLS 272
                  ||.||                .||.|..|..|.|.|..|.:|..:|.:||..|..|...
 Frog   211 ------ALQSL----------------NFQPLGRLHSLVLAGMELEHIPENAFQGLDYLESLSFF 253

  Fly   273 DNRLPAIPTAAFQRLGRLEQLNIGQNDFEVISSGAFSGLRELRHLELTGAQRLRRVESGAFSGNT 337
            ||||..:|..|.:.|..|:.|::.:|....|..|.|:|:..|..|.|...:.|.|||:.||....
 Frog   254 DNRLTEVPKEALKNLKLLKFLDLNKNPIPEIRGGDFTGMEHLEELSLNSMEELERVEAEAFQDLP 318

  Fly   338 NLEHLNLSSNKQLNELSSIAL-GGLPHLSTVVLKANQLSSLDEGLVPWADLQTL------DLSEN 395
            .|..|.:.:|.:|:.|...|. ..|..|.|::|..|:|:     :||....|.|      .|..|
 Frog   319 ELIKLEMCNNPRLSYLDPEAFSSNLGALKTLLLNNNRLA-----MVPLKIFQALPGLLEISLYSN 378

  Fly   396 PFECDCRLLW-----LRHLLVSRNASGQYAPVICAYPTALRDLPL--AHLAEPLLGCAHGAASKQ 453
            |..|||:..|     ||  |:...|:      :|..|      ||  .||.:.:.|        |
 Frog   379 PIRCDCQNCWKGLSKLR--LIEAQAT------LCINP------PLVSGHLFQEIQG--------Q 421

  Fly   454 AIIGILVVACAALITT--LALVLYTCRH---RIREMLKGHSALGRKEREYQKTFSDEEYMSRPPP 513
            |.:.    .|..||.|  :.......||   ::.....||
 Frog   422 AWLN----RCPPLIDTHLIPPQFQIARHQPVKLSCQASGH------------------------- 457

  Fly   514 GGGGVHPAAGGYPYIAGNSRMIPVTELXLEAPPPPQLRGRGG-----GGGASTASGAVQQLQVPS 573
                                  |..|:....|...::.|..|     .||:         |::..
 Frog   458 ----------------------PKPEIYWMTPHGERVTGTNGRVKINAGGS---------LEITD 491

  Fly   574 AVDQASNSF---------AQLSHIHYMTNNGQQQQAQQQQSTSKMHHSQ---QDMRLLACNGGKP 626
            ||::.|.|:         .....:....|..|:.:|......:|..||.   .:.::|:.:|..|
 Frog   492 AVEEDSGSYTCQMWNSDGTDSKSVFVSINRTQEPEAMSLLMVTKKVHSNFAVVEWKMLSGSGVSP 556

  Fly   627 -------LNATSLPRHRPPV---------VQESTLSHYSQPLANGIRLTQDHFNHNQNQS 670
                   .::.::..|.|.:         |||..|:|........:.||....:....||
 Frog   557 NVLVPFQWSSATMRIHNPHISYTAKVPLEVQEYNLTHLQPSTKYEVCLTVSSVSQPSQQS 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	5/20 (25%)
		LRR_8	96..155	CDD:404697	15/58 (26%)
		leucine-rich repeat	97..120	CDD:275380	8/22 (36%)
		leucine-rich repeat	121..144	CDD:275380	5/22 (23%)
		LRR	135..>398	CDD:443914	81/269 (30%)
		leucine-rich repeat	145..168	CDD:275380	6/22 (27%)
		leucine-rich repeat	169..192	CDD:275380	9/22 (41%)
		leucine-rich repeat	193..217	CDD:275380	6/23 (26%)
		leucine-rich repeat	218..241	CDD:275380	4/22 (18%)
		leucine-rich repeat	242..265	CDD:275380	9/22 (41%)
		leucine-rich repeat	266..289	CDD:275380	9/22 (41%)
		leucine-rich repeat	290..313	CDD:275380	7/22 (32%)
		leucine-rich repeat	314..335	CDD:275380	9/20 (45%)
		leucine-rich repeat	339..363	CDD:275380	7/24 (29%)
		LRRCT	395..445	CDD:214507	16/56 (29%)
lrrn1l	NP_001106456.1	leucine-rich repeat	60..79	CDD:275380	5/18 (28%)
		LRR	<78..419	CDD:443914	113/384 (29%)
		leucine-rich repeat	80..102	CDD:275380	6/21 (29%)
		leucine-rich repeat	103..126	CDD:275380	8/22 (36%)
		leucine-rich repeat	127..150	CDD:275380	5/22 (23%)
		leucine-rich repeat	151..174	CDD:275380	6/22 (27%)
		leucine-rich repeat	175..198	CDD:275380	9/22 (41%)
		leucine-rich repeat	199..222	CDD:275380	11/47 (23%)
		leucine-rich repeat	223..246	CDD:275380	9/22 (41%)
		leucine-rich repeat	247..294	CDD:275380	16/46 (35%)
		leucine-rich repeat	295..319	CDD:275380	9/23 (39%)
		leucine-rich repeat	320..345	CDD:275380	7/24 (29%)
		leucine-rich repeat	346..367	CDD:275380	8/25 (32%)
		leucine-rich repeat	370..382	CDD:275378	3/11 (27%)
		IG_like	437..519	CDD:214653	16/137 (12%)
		Ig strand B	448..452	CDD:409353	0/3 (0%)
		Ig strand C	461..465	CDD:409353	1/3 (33%)
		Ig strand E	485..489	CDD:409353	2/12 (17%)
		Ig strand F	499..504	CDD:409353	1/4 (25%)
		Ig strand G	512..515	CDD:409353	0/2 (0%)