Protein Alignment snky and DCST1

DIOPT Version :10

• Sequence 1: NP_648633.2
• Gene: snky / 39492
• FlyBaseID: FBgn0086916
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_689707.2
• Gene: DCST1 / 149095
• HGNCID: 26539
• Length: 706
• Species: Homo sapiens
• Alignment Length: 733
• Identity: 176/733 - (24%)
• Similarity: 301/733 - (41%)
• Gaps: 120/733 - (16%)

  Fly    21 SEGSTRIQ---CLRRFVTFLLGLVLGFLLWKLAALNFTLGRLFVN-GATDLYVFIIFVLVTG--- 78
            :.|..|.|   .::|.:|:.|.:...:.||:... .|.:..|.:. ||..|....:|.|:..
Human    10 TRGQRRKQPHTTVQRLLTWGLPVSCSWFLWRQPG-EFPVTALLLGAGAGGLLAIGLFQLLVNPMN 73

  Fly    79 ------TIFMLSL------------PVRAVILLIFVALVGKSGRTYLRAVAFAFIISGPIANLVE 125
                  .:|:.||            .:|...||:...::||.||.::...|.|.|..||:|||..
Human    74 IYEEQKIMFLYSLVGLGAMGWGTSPHIRCASLLLVPKMLGKEGRLFVLGYALAAIYVGPVANLRH 138

  Fly   126 NAGEVARVFVCTTVLTYNLSKTRFDLMAKPFTNTLKHMRGDVEEIRHTFYELQEVLVDLKYAVEN 190
            |...|.....||..|..|.::..:.:...|.....|.:....|.:|.....:.....||...|.:
Human   139 NLNNVIASLGCTVELQINNTRAAWRISTAPLRAMFKDLLSSKELLRAETRNISATFEDLDAQVNS 203

  Fly   191 SDIEDEKYGDKNTKPIYERWGRETSRMNVSEIGNGGKELPTPA-----AVQERFQRNMRNRCKHQ 250
                :..|..::|             |:..|...|.:....||     :.|:.::...:.||.:.
Human   204 ----ETGYTPEDT-------------MDSGETAQGREARQAPASRLHLSTQKMYELKTKLRCSYV 251

  Fly   251 LRSGHRACLEVFRNGYRKCTTN-FPSMIAKAICWPYRVDIICELDLFGNPDKI----CDPSAVVP 310
            :.....:|...|...:.:|..: :..::...:|.|.:....|.:      .|:    |.....|.
Human   252 VNQAILSCRRWFDRKHEQCMKHIWVPLLTHLLCLPMKFKFFCGI------AKVMEVWCRNRIPVE 310

  Fly   311 QNFGETYVELLKAEKKLFDNSSQIVVNYEIKDEQFA--KSQLKSAERTGQAFKEDFERQKRIFNK 373
            .|||:||..|.::.:.|   ..:...|.:.|:|:.|  .....|.||.....::...||:.....
Human   311 GNFGQTYDSLNQSIRGL---DGEFSANIDFKEEKQAGVLGLNTSWERVSTEVRDYVYRQEARLEW 372

  Fly   374 VMGILQKIL-CLFMLRMVYVSINYYVKYLNDVEFDNFYITKYFKHVDQRRKEQRIDAILPLRTYE 437
            .:|:|..:| |.|:| :::.|.:|...|.:|:.|||.||:.||..:|.|||:.....:||||..|
Human   373 ALGLLHVLLSCTFLL-VLHASFSYMDSYNHDIRFDNIYISTYFCQIDDRRKKLGKRTLLPLRKAE 436

  Fly   438 KSKYIDVDHIFSRTHHESTTVCF------------NLLQFLLELVTAGLFILI----DHLVVELL 486
            :.                 ||.|            |:::.|||.:...|.:::    |..:..:.
Human   437 EK-----------------TVIFPCKPTIQASEMSNVVRELLETLPILLLLVVLCGLDWALYSIF 484

  Fly   487 QIVRKRSKIVYQQDGEHEVRFNISGVGQMARLLRTTMHNFNIHEKVSTSLSNKECLPNAHVLPKK 551
            ..:|..|.:.|.....|::...:.|...:|||||.|:...|...:.....:|..|||....|..:
Human   485 DTIRHHSFLQYSFRSSHKLEVKVGGDSMLARLLRKTIGALNTSSETVMESNNMPCLPQPVGLDAR 549

  Fly   552 MYYQ-LILLYLIIIVLIYQSTTFLRMRRVICSFFYYKREKQRILFLYNRILRNR-----LRSLEF 610
            .|:: .:.:.|::.:.:.|:..: |:||||.:|::.||||:|||||||.:|:.|     ||....
Human   550 AYWRAAVPIGLLVCLCLLQAFGY-RLRRVIAAFYFPKREKKRILFLYNDLLKKRAAFTKLRRAAI 613

  Fly   611 LIHDAEDNLATHRIQQQVNVFLWLRFSCPVAFGWIRHFKFAKRTCMICRGLEDSTFTVCG--NCG 673
            |..:.:.....|.:..      .|...||:...|:      .|.|::|:..|.....||.  :|.
Human   614 LRRERQQKAPRHPLAD------ILHRGCPLLRRWL------CRRCVVCQAPETPESYVCRTLDCE 666

  Fly   674 LPYCDDCAEDLNSVCFQC 691
            ..||..|.:|:...|..|
Human   667 AVYCWSCWDDMRQRCPVC 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snky	NP_648633.2	DC_STAMP	406..597	CDD:462265	59/207 (29%)
DCST1	NP_689707.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		3/9 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..230		6/38 (16%)
		DC_STAMP	405..595	CDD:462265	59/207 (29%)