DRSC/TRiP Functional Genomics Resources

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Protein Alignment trn and Lrrtm2

DIOPT Version :9

Sequence 1:NP_001261796.1 Gene:trn / 39491 FlyBaseID:FBgn0010452 Length:751 Species:Drosophila melanogaster
Sequence 2:NP_001102939.1 Gene:Lrrtm2 / 685472 RGDID:1593785 Length:515 Species:Rattus norvegicus


Alignment Length:632 Identity:145/632 - (22%)
Similarity:222/632 - (35%) Gaps:213/632 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 MMIAFVGIWCILASIGVEPAAGLANCPPGCQCDDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSN 69
            |:.|...:..:|..:   ||.|:| |||.|:|:  .|:..|.......:|.|             
  Rat    13 MLAAIYAMSVVLKML---PALGMA-CPPKCRCE--KLLFYCDSQGFHSVPNA------------- 58

  Fly    70 KIKTIDSSIQFYAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTV 134
               |...|:.       |.|..||:..:.:..||...:|..:||:||:|..:....|.||..:..
  Rat    59 ---TDKGSLG-------LSLRHNHITALERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKE 113

  Fly   135 LNLRGNQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIF 199
            |.|..|:|..|...|||.|:.::.|:|..|::..|.|:.|.||.:|:.|:|..|:|.|:|     
  Rat   114 LILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIP----- 173

  Fly   200 QAMPSLAELFLGMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLD 264
                                ...|.|.:.|..|:|....||:::.:.|.||.:||.|.|..|:|.
  Rat   174 --------------------VRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLT 218

  Fly   265 RIPSVGLSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYL 329
            :|......:|..|..|.|..|....::.|.......|::|::.|. .:|.:....|....||:.|
  Rat   219 KINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWSTLEKLDLTGN-EIKAIDLTVFETMPNLKIL 282

  Fly   330 NLSSNKMLLEVQEGALSGLSQLKHVVLKANALTSLAEGLFPWKDLQTLDLSENPLSCDCRV---- 390
            .:.:||:                 ..|.:..|:||       :.|.|:.||.|...|..||    
  Rat   283 LMDNNKL-----------------NSLDSKILSSL-------RSLTTVGLSGNLWECSPRVCALA 323

  Fly   391 --------MWLHNLLVAKNASQDDVSELLCEFPERLRGESLRHLNPAMMGCTHADPRKQALIGAL 447
                    .|.|:              :||..|:..:||.:.........|.:.           
  Rat   324 SWLGSFQGRWEHS--------------ILCHSPDHTQGEDILDAVHGFQLCWNL----------- 363

  Fly   448 LVGSAATITALALVLYRCRHKIRETIKGGLWGNSALGRKEREYQKTFCDEDYMSRHQHH------ 506
                :.|:||:| ..||                    ....||.|       :|...:|      
  Rat   364 ----STTVTAMA-TTYR--------------------DPTTEYTK-------ISSSSYHVGDKEI 396

  Fly   507 PCSLGIHSTFPNTYTAPHHPGATHHYGMCPMPVNDLGAIDPQQKFQQLVVPTATM---------- 561
            |.:.||..|            ...|:   |.|.|.:        |.|.|: |.||          
  Rat   397 PTTAGIAVT------------TEEHF---PEPDNAI--------FTQRVI-TGTMALLFSFFFII 437

  Fly   562 ----ISEK-------------KLNNNKALVSQGAIDDSASFVLHMKS 591
                ||.|             .:.|::.|.||..        |||.:
  Rat   438 FIVFISRKCCPPTLRRIRQCSMIQNHRQLRSQTR--------LHMSN 476

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
trnNP_001261796.1 leucine-rich repeat 62..80 CDD:275380 2/17 (12%)
LRR_8 83..142 CDD:290566 18/58 (31%)
leucine-rich repeat 84..107 CDD:275380 6/22 (27%)
leucine-rich repeat 108..131 CDD:275380 9/22 (41%)
LRR_RI 129..421 CDD:238064 75/303 (25%)
LRR_8 132..190 CDD:290566 21/57 (37%)
leucine-rich repeat 132..155 CDD:275380 9/22 (41%)
leucine-rich repeat 156..179 CDD:275380 8/22 (36%)
leucine-rich repeat 180..204 CDD:275380 7/23 (30%)
LRR_8 203..263 CDD:290566 15/59 (25%)
leucine-rich repeat 205..228 CDD:275380 2/22 (9%)
leucine-rich repeat 229..252 CDD:275380 8/22 (36%)
LRR_8 252..308 CDD:290566 15/55 (27%)
leucine-rich repeat 253..276 CDD:275380 8/22 (36%)
leucine-rich repeat 277..300 CDD:275380 5/22 (23%)
leucine-rich repeat 301..322 CDD:275380 5/20 (25%)
LRR_8 325..384 CDD:290566 14/58 (24%)
leucine-rich repeat 326..350 CDD:275380 4/23 (17%)
leucine-rich repeat 351..373 CDD:275380 4/21 (19%)
Lrrtm2NP_001102939.1 LRR 1 61..83 6/28 (21%)
leucine-rich repeat 66..86 CDD:275380 6/19 (32%)
LRR_RI 73..311 CDD:238064 76/287 (26%)
LRR 2 84..107 7/22 (32%)
LRR_8 85..145 CDD:290566 21/59 (36%)
leucine-rich repeat 87..110 CDD:275380 9/22 (41%)
LRR 3 109..131 7/21 (33%)
leucine-rich repeat 111..134 CDD:275380 9/22 (41%)
LRR 4 132..155 7/22 (32%)
LRR_8 134..193 CDD:290566 20/83 (24%)
leucine-rich repeat 135..158 CDD:275380 8/22 (36%)
LRR 5 156..179 9/47 (19%)
leucine-rich repeat 159..182 CDD:275380 9/47 (19%)
LRR_8 181..241 CDD:290566 20/59 (34%)
LRR 6 181..203 6/21 (29%)
leucine-rich repeat 183..206 CDD:275380 8/22 (36%)
LRR 7 205..227 7/21 (33%)
leucine-rich repeat 207..230 CDD:275380 8/22 (36%)
LRR 8 229..251 5/21 (24%)
leucine-rich repeat 231..254 CDD:275380 5/22 (23%)
LRR 9 252..275 5/23 (22%)
LRR_8 253..312 CDD:290566 18/83 (22%)
leucine-rich repeat 255..278 CDD:275380 5/23 (22%)
LRR 10 276..299 7/39 (18%)
leucine-rich repeat 279..300 CDD:275380 6/37 (16%)
Involved in DLG4-binding 512..515
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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