Protein Alignment trn and Nepn

DIOPT Version :9

• Sequence 1: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_006512881.1
• Gene: Nepn / 66650
• MGIID: 1913900
• Length: 561
• Species: Mus musculus
• Alignment Length: 499
• Identity: 128/499 - (25%)
• Similarity: 202/499 - (40%)
• Gaps: 102/499 - (20%)

  Fly    12 IWCILASIGVEPAAGL-ANCPPGCQCDDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKIKTI- 74
            :|..|  :|:....|| ||||..|.| |:...|||  .:|..||..:..:.:||.|..::|:.:
Mouse    53 LWAFL--LGLSLTNGLSANCPGRCSC-DSMQSVQC--YRLMELPSGIPSTTKRLYISHSRIQHLQ 112

  Fly    75 ------------------------DSSIQFYAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNH 115
                                    :.:.:..:.|..|:|..|.|..:|.   |....|:.:.||.
Mouse   113 LSNFTGLLALEDFILLASGTESIENDTFKTLSTLKTLELWKNKLRQVPS---ALPANLEVLKLND 174

  Fly   116 NKIGQISNKTFIGLSAVTVLNLRGNQISELHQGTFTPLLKIEELNLGENRI-GYLDPKAFDGLSQ 179
            |.|..:....|.||..:.||.|:.|.||.|.....:||..::.|.:..|.| ..:.|.:   |..
Mouse   175 NAICALRGSEFEGLKNLKVLELKNNLISSLSPSMLSPLASLQSLMVDGNNIESVVGPLS---LPH 236

  Fly   180 LRILYLDDNALTTVPDPVIFQAMPSLAELFLGMNTLQSIQADAFQDLKGL--TRLELKGASLRNI 242
            |:.:.:::|.|..:|..| |.::.:|..|....|.|..|..:..:.|..|  .|.:||....|::
Mouse   237 LKYMSMENNQLHLIPGNV-FTSLQNLQFLSFSGNFLTKIPINLPKSLLSLKMERNQLKVVRFRDM 300

  Fly   243 SHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVN 307
            .|     |:.|..|.||:|.|..|.  |..:|..|..|.:.||..:::....   ..:|::|:.:
Mouse   301 KH-----LENLSHLYLSENFLSSID--GAQQLTNLTTLEVSQNQLQMLPPRL---PSRLQKLDCS 355

  Fly   308 GALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGALSGLSQLKHVV----------------- 355
            ... ::||....|.|..:|::|.|.:|.:.| .:.|||...|||.::.
Mouse   356 SNF-IQRVTAPEFQDLRDLKHLFLDNNVVSL-FEAGALQRCSQLSNLALEQNLLLSIPLRLPKTL 418

  Fly   356 ----LKANALTSLAE-GLFPWKDLQTLDLSE------------------------NPLSCDCRVM 391
                ||.||:..:|| .|...|.||.|:|..                        ||.:|.|.::
Mouse   419 ARLDLKGNAIQDMAERELRDLKQLQVLNLRNNRISALDFKALEGLPRLRHLYLDGNPWNCTCSLL 483

  Fly   392 WLHNLLVAKNASQDDVSELLCEFPERLRGESLRHLNPAMMGCTH 435
            ....:|.||..   ||....|..|...:|||.......:..|.|
Mouse   484 RAREVLKAKGT---DVKGGQCAAPAERQGESWMSSKKILRQCEH 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	4/42 (10%)
		LRR_8	83..142	CDD:290566	19/58 (33%)
		leucine-rich repeat	84..107	CDD:275380	7/22 (32%)
		leucine-rich repeat	108..131	CDD:275380	8/22 (36%)
		LRR_RI	129..421	CDD:238064	87/340 (26%)
		LRR_8	132..190	CDD:290566	16/58 (28%)
		leucine-rich repeat	132..155	CDD:275380	9/22 (41%)
		leucine-rich repeat	156..179	CDD:275380	5/23 (22%)
		leucine-rich repeat	180..204	CDD:275380	6/23 (26%)
		LRR_8	203..263	CDD:290566	18/61 (30%)
		leucine-rich repeat	205..228	CDD:275380	6/22 (27%)
		leucine-rich repeat	229..252	CDD:275380	7/24 (29%)
		LRR_8	252..308	CDD:290566	15/55 (27%)
		leucine-rich repeat	253..276	CDD:275380	9/22 (41%)
		leucine-rich repeat	277..300	CDD:275380	4/22 (18%)
		leucine-rich repeat	301..322	CDD:275380	5/20 (25%)
		LRR_8	325..384	CDD:290566	24/104 (23%)
		leucine-rich repeat	326..350	CDD:275380	8/23 (35%)
		leucine-rich repeat	351..373	CDD:275380	8/43 (19%)
Nepn	XP_006512881.1	leucine-rich repeat	101..121	CDD:275380	3/19 (16%)
		leucine-rich repeat	122..145	CDD:275380	0/22 (0%)
		leucine-rich repeat	146..166	CDD:275380	7/22 (32%)
		PRK15370	<148..>367	CDD:185268	64/236 (27%)
		leucine-rich repeat	167..190	CDD:275380	8/22 (36%)
		leucine-rich repeat	191..214	CDD:275380	9/22 (41%)
		leucine-rich repeat	215..236	CDD:275380	5/23 (22%)
		leucine-rich repeat	237..260	CDD:275380	6/23 (26%)
		leucine-rich repeat	261..305	CDD:275380	13/48 (27%)
		PRK15370	<271..>474	CDD:185268	52/214 (24%)
		leucine-rich repeat	282..297	CDD:275380	5/14 (36%)
		leucine-rich repeat	306..327	CDD:275380	9/22 (41%)
		leucine-rich repeat	328..348	CDD:275380	4/22 (18%)
		leucine-rich repeat	349..372	CDD:275380	6/23 (26%)
		leucine-rich repeat	373..396	CDD:275380	8/23 (35%)
		leucine-rich repeat	397..420	CDD:275380	1/22 (5%)
		leucine-rich repeat	421..441	CDD:275380	7/19 (37%)
		leucine-rich repeat	442..465	CDD:275380	4/22 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100