DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment trn and BGN

DIOPT Version :9

Sequence 1:NP_001261796.1 Gene:trn / 39491 FlyBaseID:FBgn0010452 Length:751 Species:Drosophila melanogaster
Sequence 2:NP_001702.1 Gene:BGN / 633 HGNCID:1044 Length:368 Species:Homo sapiens


Alignment Length:288 Identity:86/288 - (29%)
Similarity:144/288 - (50%) Gaps:21/288 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 ANCPPGCQCDDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKIKTI-DSSIQFYAELTFLDLSS 91
            |.||.||.|  :..||||.:..|..:|..::|....|.:::|.|..: ....:....|..|.|.:
Human    61 AMCPFGCHC--HLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVN 123

  Fly    92 NHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRGNQISELHQGTFTPLLKI 156
            |.:..|.::.|:..:|||:::::.|.:.:|....   .|::..|.:..|:|.::.:|.|:.|..:
Human   124 NKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNL---PSSLVELRIHDNRIRKVPKGVFSGLRNM 185

  Fly   157 EELNLGENRI---GYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMP-SLAELFLGMNTLQS 217
            ..:.:|.|.:   |: :|.||||| :|..|.:.:..||.:|     :.:| :|.||.|..|.:|:
Human   186 NCIEMGGNPLENSGF-EPGAFDGL-KLNYLRISEAKLTGIP-----KDLPETLNELHLDHNKIQA 243

  Fly   218 IQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRLEQLSL 282
            |:.:.......|.||.|....:|.|.:.|...|..||.|.|.:|:|.|:|| ||..|..|:.:.|
Human   244 IELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPS-GLPDLKLLQVVYL 307

  Fly   283 GQNDFEVISEGAF--MGLKQLKRLEVNG 308
            ..|:...:....|  ||. .:||...||
Human   308 HSNNITKVGVNDFCPMGF-GVKRAYYNG 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
trnNP_001261796.1 leucine-rich repeat 62..80 CDD:275380 3/18 (17%)
LRR_8 83..142 CDD:290566 14/58 (24%)
leucine-rich repeat 84..107 CDD:275380 6/22 (27%)
leucine-rich repeat 108..131 CDD:275380 4/22 (18%)
LRR_RI 129..421 CDD:238064 59/186 (32%)
LRR_8 132..190 CDD:290566 17/60 (28%)
leucine-rich repeat 132..155 CDD:275380 6/22 (27%)
leucine-rich repeat 156..179 CDD:275380 9/25 (36%)
leucine-rich repeat 180..204 CDD:275380 6/24 (25%)
LRR_8 203..263 CDD:290566 21/60 (35%)
leucine-rich repeat 205..228 CDD:275380 7/22 (32%)
leucine-rich repeat 229..252 CDD:275380 8/22 (36%)
LRR_8 252..308 CDD:290566 20/57 (35%)
leucine-rich repeat 253..276 CDD:275380 12/22 (55%)
leucine-rich repeat 277..300 CDD:275380 6/24 (25%)
leucine-rich repeat 301..322 CDD:275380 4/8 (50%)
LRR_8 325..384 CDD:290566
leucine-rich repeat 326..350 CDD:275380
leucine-rich repeat 351..373 CDD:275380
BGNNP_001702.1 NEL <64..>297 CDD:330839 72/245 (29%)
leucine-rich repeat 71..91 CDD:275380 6/19 (32%)
LRR 1 82..102 4/19 (21%)
leucine-rich repeat 92..115 CDD:275380 3/22 (14%)
LRR 2 103..126 4/22 (18%)
leucine-rich repeat 116..139 CDD:275380 6/22 (27%)
LRR 3 127..150 6/22 (27%)
leucine-rich repeat 140..160 CDD:275380 4/22 (18%)
LRR 4 151..171 4/22 (18%)
leucine-rich repeat 161..184 CDD:275380 6/22 (27%)
LRR 5 172..195 5/22 (23%)
leucine-rich repeat 185..208 CDD:275380 7/23 (30%)
LRR 6 196..220 9/25 (36%)
leucine-rich repeat 210..231 CDD:275380 6/25 (24%)
LRR 7 221..241 8/24 (33%)
leucine-rich repeat 233..254 CDD:275380 6/20 (30%)
LRR 8 242..265 6/22 (27%)
leucine-rich repeat 255..278 CDD:275380 8/22 (36%)
LRR 9 266..289 9/22 (41%)
LRR_8 277..>323 CDD:316378 16/46 (35%)
LRR 10 290..312 9/22 (41%)
leucine-rich repeat 302..315 CDD:275378 3/12 (25%)
LRR 11 313..342 7/23 (30%)
LRR 12 343..368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.