Protein Alignment trn and NYX

DIOPT Version :9

• Sequence 1: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001365406.2
• Gene: NYX / 60506
• HGNCID: 8082
• Length: 476
• Species: Homo sapiens
• Alignment Length: 474
• Identity: 128/474 - (27%)
• Similarity: 189/474 - (39%)
• Gaps: 82/474 - (17%)

  Fly    30 CPPGCQCD--DNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKIKTIDSSIQFYAELTFLDLSSN 92
            ||..|.|.  :....|:|....|..:|..|.                       .|...:||..|
Human    26 CPAACACSTVERGCSVRCDRAGLLRVPAELP-----------------------CEAVSIDLDRN 67

  Fly    93 HLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRGNQISELHQGTFTPLLKIE 157
            .|..:.:|.|.....|:.:.|.||           .||.:|             .|.|..|.::.
Human    68 GLRFLGERAFGTLPSLRRLSLRHN-----------NLSFIT-------------PGAFKGLPRLA 108

  Fly   158 ELNLGEN-RIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMPSLAELFLGMNTLQSIQAD 221
            ||.|..| .:.||..:.|..||:||.|.|....|.:||:.::.: :|:|.||....|..:.:..
Human   109 ELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLLAE-LPALRELAAFDNLFRRVPG- 171

  Fly   222 AFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRLEQLSLGQND 286
            |.:.|..||...|:...:..::..|..||:.||.|.|..||:..:.:........||.|.|..|.
Human   172 ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNL 236

  Fly   287 FEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGALSGLSQL 351
            ...:...||.||::|:.|.:.|. .|.||....|:|...||.|.|..|.:.. |:|||...||.|
Human   237 LAELPADAFRGLRRLRTLNLGGN-ALDRVARAWFADLAELELLYLDRNSIAF-VEEGAFQNLSGL 299

  Fly   352 KHVVLKANALTSLAEGLF-PWKDLQTLDLSENPLSCDCRVMWLHNLLVAKNASQDDVSELLCEFP 415
            ..:.|..|.||.||...| |...|..|.|..||..||||:.||.:.:.....    |:::.|..|
Human   300 LALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNPWCCDCRLEWLRDWMEGSGR----VTDVPCASP 360

  Fly   416 ERLRGESLRH-----------LNPAMMGCTHADPRKQALIGALLVGSAATITALALVLYRC---R 466
            ..:.|..|..           ::|..:..|.:.|      |.....:|.|::..:.:|.:.   |
Human   361 GSVAGLDLSQVTFGRSSDGLCVDPEELNLTTSSP------GPSPEPAATTVSRFSSLLSKLLAPR 419

  Fly   467 HKIRETIK--GGLWGNSAL 483
            ..:.|...  ||| .|::|
Human   420 VPVEEAANTTGGL-ANASL 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	0/17 (0%)
		LRR_8	83..142	CDD:290566	14/58 (24%)
		leucine-rich repeat	84..107	CDD:275380	6/22 (27%)
		leucine-rich repeat	108..131	CDD:275380	5/22 (23%)
		LRR_RI	129..421	CDD:238064	92/293 (31%)
		LRR_8	132..190	CDD:290566	17/58 (29%)
		leucine-rich repeat	132..155	CDD:275380	4/22 (18%)
		leucine-rich repeat	156..179	CDD:275380	8/23 (35%)
		leucine-rich repeat	180..204	CDD:275380	7/23 (30%)
		LRR_8	203..263	CDD:290566	18/59 (31%)
		leucine-rich repeat	205..228	CDD:275380	6/22 (27%)
		leucine-rich repeat	229..252	CDD:275380	6/22 (27%)
		LRR_8	252..308	CDD:290566	17/55 (31%)
		leucine-rich repeat	253..276	CDD:275380	6/22 (27%)
		leucine-rich repeat	277..300	CDD:275380	9/22 (41%)
		leucine-rich repeat	301..322	CDD:275380	7/20 (35%)
		LRR_8	325..384	CDD:290566	24/59 (41%)
		leucine-rich repeat	326..350	CDD:275380	10/23 (43%)
		leucine-rich repeat	351..373	CDD:275380	9/22 (41%)
NYX	NP_001365406.2	LRR_8	61..115	CDD:404697	19/77 (25%)
		leucine-rich repeat	63..82	CDD:275380	6/18 (33%)
		leucine-rich repeat	83..106	CDD:275380	10/46 (22%)
		leucine-rich repeat	107..131	CDD:275380	8/23 (35%)
		leucine-rich repeat	132..155	CDD:275380	7/23 (30%)
		PPP1R42	150..310	CDD:411060	50/163 (31%)
		leucine-rich repeat	156..178	CDD:275380	6/22 (27%)
		leucine-rich repeat	179..202	CDD:275380	6/22 (27%)
		leucine-rich repeat	203..226	CDD:275380	6/22 (27%)
		LRR_8	227..285	CDD:404697	22/58 (38%)
		leucine-rich repeat	227..250	CDD:275380	9/22 (41%)
		leucine-rich repeat	251..274	CDD:275380	8/23 (35%)
		leucine-rich repeat	275..296	CDD:275380	9/21 (43%)
		leucine-rich repeat	323..335	CDD:275378	5/11 (45%)
		LRRCT	331..>365	CDD:214507	11/37 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010