DRSC/TRiP Functional Genomics Resources

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Protein Alignment trn and Flrt1

DIOPT Version :9

Sequence 1:NP_001261796.1 Gene:trn / 39491 FlyBaseID:FBgn0010452 Length:751 Species:Drosophila melanogaster
Sequence 2:NP_001102630.1 Gene:Flrt1 / 499308 RGDID:1565152 Length:674 Species:Rattus norvegicus


Alignment Length:456 Identity:115/456 - (25%)
Similarity:181/456 - (39%) Gaps:106/456 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 CPPGCQCDDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKIKT--IDSSIQFYAELTFLDLSSN 92
            ||..|:||:.  .:.|.:..|..:|..:......|.:::|:|..  |...::...::..:.|..|
  Rat    54 CPSVCRCDNG--FIYCNDRGLTSIPSDIPDDATTLYLQNNQINNAGIPQDLKTKVKVQVIYLYEN 116

  Fly    93 HLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRGNQISELHQGTFTPLLKIE 157
            .|...|   ....:.|:|:||..|.:..|:..:...:..:..|:|..|.:|         .:.||
  Rat   117 DLDEFP---INLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVS---------TVSIE 169

  Fly   158 ELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMP-SLAELFLGMNTLQSIQAD 221
            |             .||....||::|:|..|.|:::|     ..:| :|.||.|..|.:.:|...
  Rat   170 E-------------DAFADSKQLKLLFLSRNHLSSIP-----SGLPHTLEELRLDDNRISTIPLH 216

  Fly   222 AFQDLKGLTRLELKGASLRN--ISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRLEQLSLGQ 284
            ||:.|..|.||.|.|..|.|  |:.|:|..||.|..|.|..|.| ..|.:.|.. ..|::|.|..
  Rat   217 AFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSL-AAPPLNLPS-AHLQKLYLQD 279

  Fly   285 NDFEVISEGAFMGLKQLKRLEV--NGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGALSG 347
            |....|.......:::|:||::  |....|.|   |.|.|.|||..|.|.:|             
  Rat   280 NAISHIPYNTLAKMRELERLDLSNNNLTTLPR---GLFDDLGNLAQLLLRNN------------- 328

  Fly   348 LSQLKHVVLKANALTSLAEGLFPWKDLQTLDLSENPLSCDCRVMWLHNLLVAKNASQDDVSELLC 412
                                  ||             .|.|.:|||.:.:.|: |:..:|..|:|
  Rat   329 ----------------------PW-------------FCGCNLMWLRDWVKAR-AAVVNVRGLMC 357

  Fly   413 EFPERLRGESLRHLNPAMMGCTHADPRKQALIGALLVGSAATITALALVLYRCRHKIRETIKGGL 477
            :.||::||.:::.:...|..|..|..:          ||||...|....   ..|....|.:|.|
  Rat   358 QGPEKVRGMAIKDITSEMDECFEAGSQ----------GSAANAAAKTTA---SNHASATTPQGSL 409

  Fly   478 W 478
            :
  Rat   410 F 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
trnNP_001261796.1 leucine-rich repeat 62..80 CDD:275380 4/19 (21%)
LRR_8 83..142 CDD:290566 13/58 (22%)
leucine-rich repeat 84..107 CDD:275380 4/22 (18%)
leucine-rich repeat 108..131 CDD:275380 6/22 (27%)
LRR_RI 129..421 CDD:238064 80/296 (27%)
LRR_8 132..190 CDD:290566 14/57 (25%)
leucine-rich repeat 132..155 CDD:275380 4/22 (18%)
leucine-rich repeat 156..179 CDD:275380 5/22 (23%)
leucine-rich repeat 180..204 CDD:275380 7/24 (29%)
LRR_8 203..263 CDD:290566 26/62 (42%)
leucine-rich repeat 205..228 CDD:275380 9/22 (41%)
leucine-rich repeat 229..252 CDD:275380 11/24 (46%)
LRR_8 252..308 CDD:290566 15/57 (26%)
leucine-rich repeat 253..276 CDD:275380 7/22 (32%)
leucine-rich repeat 277..300 CDD:275380 5/22 (23%)
leucine-rich repeat 301..322 CDD:275380 8/22 (36%)
LRR_8 325..384 CDD:290566 7/58 (12%)
leucine-rich repeat 326..350 CDD:275380 4/23 (17%)
leucine-rich repeat 351..373 CDD:275380 2/21 (10%)
Flrt1NP_001102630.1 PRK15370 <58..>329 CDD:185268 85/342 (25%)
leucine-rich repeat 108..128 CDD:275380 4/22 (18%)
leucine-rich repeat 129..152 CDD:275380 6/22 (27%)
leucine-rich repeat 153..178 CDD:275380 9/46 (20%)
leucine-rich repeat 179..199 CDD:275380 7/24 (29%)
leucine-rich repeat 200..223 CDD:275380 9/22 (41%)
leucine-rich repeat 224..249 CDD:275380 11/24 (46%)
leucine-rich repeat 250..271 CDD:275380 7/22 (32%)
leucine-rich repeat 272..295 CDD:275380 5/22 (23%)
leucine-rich repeat 296..319 CDD:275380 9/25 (36%)
PCC 300..>386 CDD:188093 31/147 (21%)
FN3 441..505 CDD:214495
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
32.870

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