DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trn and CG18249

DIOPT Version :9

Sequence 1:	NP_001261796.1	Gene:	trn / 39491	FlyBaseID:	FBgn0010452	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_001163549.1	Gene:	CG18249 / 40964	FlyBaseID:	FBgn0037553	Length:	559	Species:	Drosophila melanogaster

Alignment Length:	462	Identity:	116/462 - (25%)
Similarity:	180/462 - (38%)	Gaps:	126/462 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SIGVEPAAG----LANCPPG-CQCDDNTLVV--------------QCGEGQLDVLPIALNPSIQR 63
            ::.|..|:|    .|:||.. |...|..:..              .|....:..|.:.|.|.::.
  Fly    19 ALAVYDASGRFNLSASCPDSFCSLSDRPVAYSATPALQLRELHLRNCSRQSITWLVLQLTPGLRT 83

  Fly    64 LVIKSNKIKTID-SSIQFYAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFI 127
            |||::.....|. .|::....||.|.:....|..:..:.|....:|:.:.|:.|.|..:....|.
  Fly    84 LVIRNCATYHISKESLRPVENLTSLQMQGTSLGVLRDQIFNAVPRLEILQLSQNFIHTVHVAAFQ 148

  Fly   128 GLSAVTVLNLRGNQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNAL-T 191
            |||.:.:|.|:||.|:|:...|..||:::..|:|..|.:..|....|....:|:.|.|:.|.| .
  Fly   149 GLSKLRLLGLQGNAIAEILSSTLDPLMELVHLDLSRNELTTLPQNIFAKNKKLQTLLLNGNPLRI 213

  Fly   192 TVPDPVIFQAMPSLAELFLG------MNTLQSIQADAFQDLKGLTRLELKGASLRNI-------- 242
            .:||  :..::|:|..|.||      :.||         :|..:..|.|:|:||.::
  Fly   214 LMPD--VLGSLPNLRLLDLGHAAELEVMTL---------NLTNVQNLVLEGSSLSSLVINGGFIK 267

  Fly   243 -----------------------SHDSFL----------GLQELRILDLSDNRLDRIPSVG---- 270
                                   .|.:.|          |:..|:.||||.||::.:|..|
  Fly   268 LQAGNNELNHLQVGNKSSVIEMDLHGNLLNGNDTAALLRGMWNLQRLDLSKNRIEALPQHGSGLD 332

  Fly   271 ------LSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYL 329
                  |..|..|:.|:|..|              ||.||.....:...|           |.||
  Fly   333 ASGTQELLILPSLKFLNLANN--------------QLVRLPPESPILSSR-----------LSYL 372

  Fly   330 NLSSNKML-LEVQEGALSGLSQLKHVVLKANALTS-----LAEGLFPWKDLQTLDLSENPLSCDC 388
            :||.|.|| |:|  ..|..||.||.:.::.|.|.:     |.|   ...||..|.|.:||.|...
  Fly   373 DLSHNLMLTLDV--AILRSLSVLKGLYVEGNRLNTINYQKLHE---EHPDLSELGLHDNPWSSGL 432

  Fly   389 -RVMWLH 394
             |.|:|:
  Fly   433 YRKMFLY 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	5/18 (28%)
		LRR_8	83..142	CDD:290566	17/58 (29%)
		leucine-rich repeat	84..107	CDD:275380	5/22 (23%)
		leucine-rich repeat	108..131	CDD:275380	7/22 (32%)
		LRR_RI	129..421	CDD:238064	88/331 (27%)
		LRR_8	132..190	CDD:290566	18/57 (32%)
		leucine-rich repeat	132..155	CDD:275380	9/22 (41%)
		leucine-rich repeat	156..179	CDD:275380	5/22 (23%)
		leucine-rich repeat	180..204	CDD:275380	7/24 (29%)
		LRR_8	203..263	CDD:290566	22/106 (21%)
		leucine-rich repeat	205..228	CDD:275380	7/28 (25%)
		leucine-rich repeat	229..252	CDD:275380	8/63 (13%)
		LRR_8	252..308	CDD:290566	19/65 (29%)
		leucine-rich repeat	253..276	CDD:275380	11/32 (34%)
		leucine-rich repeat	277..300	CDD:275380	4/22 (18%)
		leucine-rich repeat	301..322	CDD:275380	4/20 (20%)
		LRR_8	325..384	CDD:290566	24/64 (38%)
		leucine-rich repeat	326..350	CDD:275380	12/24 (50%)
		leucine-rich repeat	351..373	CDD:275380	6/26 (23%)
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380	3/22 (14%)
		LRR_8	104..163	CDD:290566	17/58 (29%)
		leucine-rich repeat	105..128	CDD:275380	5/22 (23%)
		LRR_RI	107..438	CDD:238064	96/371 (26%)
		leucine-rich repeat	129..152	CDD:275380	7/22 (32%)
		leucine-rich repeat	153..176	CDD:275380	9/22 (41%)
		LRR_8	176..232	CDD:290566	16/57 (28%)
		leucine-rich repeat	177..200	CDD:275380	5/22 (23%)
		leucine-rich repeat	201..224	CDD:275380	7/24 (29%)
		leucine-rich repeat	225..258	CDD:275380	12/41 (29%)
		leucine-rich repeat	259..310	CDD:275380	3/50 (6%)
		leucine-rich repeat	311..344	CDD:275380	11/32 (34%)
		LRR_8	343..403	CDD:290566	25/86 (29%)
		leucine-rich repeat	345..368	CDD:275380	8/36 (22%)
		leucine-rich repeat	369..390	CDD:275380	11/22 (50%)
		leucine-rich repeat	393..417	CDD:275380	6/26 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453588
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840