DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment trn and CG7800

DIOPT Version :9

Sequence 1:	NP_001261796.1	Gene:	trn / 39491	FlyBaseID:	FBgn0010452	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_649770.1	Gene:	CG7800 / 40963	FlyBaseID:	FBgn0037552	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	354	Identity:	96/354 - (27%)
Similarity:	144/354 - (40%)	Gaps:	89/354 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 RTFAYQK--KLQEVHLNH---------------------------NKIGQISNKTFIGLSAVTVL 135
            |||:.:|  ||.|.|::.                           |.:.|        |..:|.|
  Fly    36 RTFSDKKATKLTEFHMDSCEKKVLKLMPNLRTLELENCDSPDFTMNDLNQ--------LPYLTSL 92

  Fly   136 NLRGNQISELHQGTFT--PLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVI 198
            .||...:..||...|:  |.:||  |.||.|.|..|..:.|.||:||.:|.|..|.:..:|..|
  Fly    93 QLRRGNLLGLHDEHFSKWPNMKI--LMLGGNNITRLSNECFKGLAQLWLLSLPGNGIQGLPWDV- 154

  Fly   199 FQAMPSLAELFLGMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLS---- 259
            ||.:|.|..|.|..|.::::..:.|..:..|..|.|.|..|..|:..|...|..||:||:|
  Fly   155 FQNLPELLHLDLSGNRIETLHENIFTGVPKLEMLLLNGNPLTWIAPTSLKSLSNLRLLDMSNCGP 219

  Fly   260 --------------DN----RLDRIPSVGLSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEV 306
                          ||    |||.:.||        .:|...:|.   |:|........:..|::
  Fly   220 LPDLSLPGAHTLILDNSGVQRLDILGSV--------HKLQARKNH---ITEIKLPDKSSVIELDL 273

  Fly   307 NG----ALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGA-----LSGLSQLKHVVLKANALT 362
            :.    |..:.:::||.:    .|:.|:||.|.:.:....|:     |..|..|.::.|.||.||
  Fly   274 HSNLLTATDIPKLLTGMW----RLQRLDLSENIIGIYAAAGSDNTSELFILPNLMYMNLSANRLT 334

  Fly   363 SL-AEGLFPWKDLQTLDLSENPLSCDCRV 390
            .| .:...||:.|..||.|.|.:....:|
  Fly   335 RLHFDSPIPWERLTHLDASYNRIYAPAKV 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380
		LRR_8	83..142	CDD:290566	15/70 (21%)
		leucine-rich repeat	84..107	CDD:275380	4/8 (50%)
		leucine-rich repeat	108..131	CDD:275380	6/49 (12%)
		LRR_RI	129..421	CDD:238064	86/296 (29%)
		LRR_8	132..190	CDD:290566	24/59 (41%)
		leucine-rich repeat	132..155	CDD:275380	8/24 (33%)
		leucine-rich repeat	156..179	CDD:275380	10/22 (45%)
		leucine-rich repeat	180..204	CDD:275380	8/23 (35%)
		LRR_8	203..263	CDD:290566	21/81 (26%)
		leucine-rich repeat	205..228	CDD:275380	5/22 (23%)
		leucine-rich repeat	229..252	CDD:275380	8/22 (36%)
		LRR_8	252..308	CDD:290566	17/77 (22%)
		leucine-rich repeat	253..276	CDD:275380	12/44 (27%)
		leucine-rich repeat	277..300	CDD:275380	4/22 (18%)
		leucine-rich repeat	301..322	CDD:275380	4/24 (17%)
		LRR_8	325..384	CDD:290566	22/64 (34%)
		leucine-rich repeat	326..350	CDD:275380	8/28 (29%)
		leucine-rich repeat	351..373	CDD:275380	9/22 (41%)
CG7800	NP_649770.1	leucine-rich repeat	46..64	CDD:275380	3/17 (18%)
		leucine-rich repeat	65..85	CDD:275380	1/19 (5%)
		LRR_8	87..147	CDD:290566	24/61 (39%)
		leucine-rich repeat	89..112	CDD:275380	7/22 (32%)
		leucine-rich repeat	113..136	CDD:275380	11/24 (46%)
		LRR_RI	<131..334	CDD:238064	58/218 (27%)
		leucine-rich repeat	137..160	CDD:275380	8/23 (35%)
		LRR_8	140..195	CDD:290566	17/55 (31%)
		leucine-rich repeat	161..184	CDD:275380	5/22 (23%)
		leucine-rich repeat	185..208	CDD:275380	8/22 (36%)
		leucine-rich repeat	209..246	CDD:275380	10/36 (28%)
		leucine-rich repeat	247..267	CDD:275380	5/30 (17%)
		leucine-rich repeat	268..292	CDD:275380	4/27 (15%)
		leucine-rich repeat	293..322	CDD:275380	8/28 (29%)
		leucine-rich repeat	395..406	CDD:275378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453587
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930