DRSC/TRiP Functional Genomics Resources

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Protein Alignment trn and rtn4rl2b

DIOPT Version :9

Sequence 1:NP_001261796.1 Gene:trn / 39491 FlyBaseID:FBgn0010452 Length:751 Species:Drosophila melanogaster
Sequence 2:NP_982350.1 Gene:rtn4rl2b / 403309 ZFINID:ZDB-GENE-040310-2 Length:457 Species:Danio rerio


Alignment Length:558 Identity:124/558 - (22%)
Similarity:191/558 - (34%) Gaps:186/558 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 IWCILASIGVEPAAGLANCPPGCQCDDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKIKTIDS 76
            :|.::..:....|.|.| ||..|.|....:.|.|.......:|..:....||:.:::|:|..:.:
Zfish    24 LWLVIWLLACRCAPGQA-CPRLCVCYHMPMTVSCQSQNFTSVPAGVPYDSQRVFLQNNRITELRA 87

  Fly    77 SIQFYAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRGNQ 141
            .                       :|.::.:                          ||.|..|.
Zfish    88 D-----------------------SFGFETQ--------------------------VLWLYSNN 103

  Fly   142 ISELHQGTFTPLLKIEELNLGEN-RIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMPSL 205
            |:.:..|.|:.|..:|||:|.:| .:..||..||.||.:|:.|::....||.:|           
Zfish   104 ITWIEAGAFSNLRVLEELDLSDNPSLRRLDGGAFRGLERLQSLHMHRCHLTELP----------- 157

  Fly   206 AELFLGMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVG 270
            |:||..:.:||                              ||.|||        |:|..:|...
Zfish   158 ADLFHKLYSLQ------------------------------FLYLQE--------NQLTNLPDGL 184

  Fly   271 LSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNK 335
            .|.||.|..|.|..|....:||.||.||..|.||.::.. |:::|...:|.|.|.|..|.|.:|.
Zfish   185 FSDLVNLTHLFLHGNRIRTVSENAFRGLVNLDRLLLHDN-RIRQVHRRSFRDLGRLTILYLFNNS 248

  Fly   336 MLLEVQEGALSGLSQLKHVVLKANALTSLAEGLFPWKDLQTLDLSENPLSCDCRVM----WLHNL 396
            :    ||             |...||...:       .:|.|.|:.||.:|.|...    |....
Zfish   249 L----QE-------------LPGQALRDTS-------SVQFLRLNGNPWTCGCEARSLWEWFRKA 289

  Fly   397 LVAKNASQDDVSELLCEFPERLRGESLRHLNPAMMG-CTHADPRKQALIGALLVGSAATITALAL 460
            .::.       |:|.|..|...:|:.||.|...... |...||...|       |:..|..:...
Zfish   290 RISS-------SDLTCSSPAPRKGQDLRFLRELDFALCPLPDPGSMA-------GTTTTTFSTKT 340

  Fly   461 VLYRCR-----------HKIRETIKGGLWGN---------------------SALGRKE-REYQK 492
            ..:..:           ||..||:|...:.:                     :||.:.| .||..
Zfish   341 RWWFSKNKPASSSKSHFHKSSETLKAFPFNSGKNPSSSSTSFSSKYDLTAEEAALPKLEPEEYWA 405

  Fly   493 TFCDEDYMS-RHQHHPCSLGIHSTFPNTYTAPHHPGAT 529
            .:.:||..| |.....|        |..|.:|..|.::
Zfish   406 NYGNEDAASVRCFELEC--------PPGYDSPILPSSS 435

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
trnNP_001261796.1 leucine-rich repeat 62..80 CDD:275380 4/17 (24%)
LRR_8 83..142 CDD:290566 5/58 (9%)
leucine-rich repeat 84..107 CDD:275380 1/22 (5%)
leucine-rich repeat 108..131 CDD:275380 0/22 (0%)
LRR_RI 129..421 CDD:238064 79/296 (27%)
LRR_8 132..190 CDD:290566 21/58 (36%)
leucine-rich repeat 132..155 CDD:275380 8/22 (36%)
leucine-rich repeat 156..179 CDD:275380 11/23 (48%)
leucine-rich repeat 180..204 CDD:275380 5/23 (22%)
LRR_8 203..263 CDD:290566 11/59 (19%)
leucine-rich repeat 205..228 CDD:275380 5/22 (23%)
leucine-rich repeat 229..252 CDD:275380 3/22 (14%)
LRR_8 252..308 CDD:290566 20/55 (36%)
leucine-rich repeat 253..276 CDD:275380 5/22 (23%)
leucine-rich repeat 277..300 CDD:275380 10/22 (45%)
leucine-rich repeat 301..322 CDD:275380 6/20 (30%)
LRR_8 325..384 CDD:290566 13/58 (22%)
leucine-rich repeat 326..350 CDD:275380 6/23 (26%)
leucine-rich repeat 351..373 CDD:275380 3/21 (14%)
rtn4rl2bNP_982350.1 LRRNT 40..71 CDD:214470 8/31 (26%)
leucine-rich repeat 53..70 CDD:275380 3/16 (19%)
leucine-rich repeat 73..93 CDD:275380 5/42 (12%)
LRR_RI 93..>326 CDD:238064 85/339 (25%)
LRR_8 95..153 CDD:290566 21/83 (25%)
leucine-rich repeat 95..117 CDD:275380 8/47 (17%)
leucine-rich repeat 118..142 CDD:275380 11/23 (48%)
leucine-rich repeat 143..166 CDD:275380 8/33 (24%)
LRR_8 166..225 CDD:290566 26/97 (27%)
LRR_4 166..206 CDD:289563 17/77 (22%)
leucine-rich repeat 167..190 CDD:275380 12/60 (20%)
leucine-rich repeat 191..214 CDD:275380 10/22 (45%)
LRR_8 214..272 CDD:290566 20/82 (24%)
leucine-rich repeat 215..238 CDD:275380 7/23 (30%)
leucine-rich repeat 239..262 CDD:275380 9/46 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24373
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
22.010

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