DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment trn and Chad

DIOPT Version :9

Sequence 1:NP_001261796.1 Gene:trn / 39491 FlyBaseID:FBgn0010452 Length:751 Species:Drosophila melanogaster
Sequence 2:NP_062037.1 Gene:Chad / 29195 RGDID:2336 Length:358 Species:Rattus norvegicus


Alignment Length:451 Identity:120/451 - (26%)
Similarity:186/451 - (41%) Gaps:108/451 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MQRNMMIAFVGIWCILASIGVEPAAGLANCPPGCQCDDNTLVVQCGEGQLDVLPIA------LNP 59
            |.|.::::.|.:..:|      ||  ||.||..|.|..:...|.|.:..|..:|..      || 
  Rat     1 MARVLLLSLVFLAILL------PA--LAACPQNCHCHGDLQHVICDKVGLQKIPKVSETTKLLN- 56

  Fly    60 SIQR---LVIKSNKIKTIDSSIQFYAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQI 121
             :||   .|:.:|..:|:.:       |..|.|...::..:....|...|:|..::|:||.|..:
  Rat    57 -LQRNNFPVLAANSFRTVPN-------LVSLHLQHCNIREVAAGAFRGLKQLIYLYLSHNDIRVL 113

  Fly   122 SNKTFIGLSAVTVLNLRGNQISELHQGTFTPLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLD 186
            ....|..|:.:|.|.|..|::|||.:|..:||:.:..|.|..|:|..|...||.|...||.|||.
  Rat   114 RAGAFDDLTELTYLYLDHNKVSELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLS 178

  Fly   187 DNALTTVPDPVIFQAMPSLAELFLGMNTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQ 251
            :||||                         |:...:..|::.|.:..                  
  Rat   179 ENALT-------------------------SLHPGSLDDVENLAKFH------------------ 200

  Fly   252 ELRILDLSDNRLDRIPSVGLSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVM 316
                  |..|:|...||..||||..:|:|.|..|..:.|.:.||..              ..|.:
  Rat   201 ------LDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQS--------------FGRYL 245

  Fly   317 TGAFSDNGNLEYLNLSSNKMLLEVQEGALSGLSQLKHVVLKANALTSLAEGLFPWKDLQTLDLSE 381
            ...:.||.|||           :..:.|.:|::.||||.|:.|.|..| ...||:.:|:||.|:.
  Rat   246 ETLWLDNTNLE-----------KFSDAAFAGVTTLKHVHLENNRLNQL-PSTFPFDNLETLTLTN 298

  Fly   382 NPLSCDCRVMWLHNLLVAKNASQDDVSELLCEFPERLRGESLRHLNPAMMGCTHADPRKQA 442
            ||..|.|::..|...|.||.:..|    ..|..|.:.:|:.:|..: |:..|  ..|.|::
  Rat   299 NPWKCTCQLRGLRRWLEAKTSRPD----ATCSSPAKFKGQRIRDTD-ALRSC--KSPTKRS 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
trnNP_001261796.1 leucine-rich repeat 62..80 CDD:275380 5/20 (25%)
LRR_8 83..142 CDD:290566 16/58 (28%)
leucine-rich repeat 84..107 CDD:275380 4/22 (18%)
leucine-rich repeat 108..131 CDD:275380 7/22 (32%)
LRR_RI 129..421 CDD:238064 80/291 (27%)
LRR_8 132..190 CDD:290566 24/57 (42%)
leucine-rich repeat 132..155 CDD:275380 10/22 (45%)
leucine-rich repeat 156..179 CDD:275380 8/22 (36%)
leucine-rich repeat 180..204 CDD:275380 9/23 (39%)
LRR_8 203..263 CDD:290566 5/59 (8%)
leucine-rich repeat 205..228 CDD:275380 2/22 (9%)
leucine-rich repeat 229..252 CDD:275380 1/22 (5%)
LRR_8 252..308 CDD:290566 16/55 (29%)
leucine-rich repeat 253..276 CDD:275380 9/22 (41%)
leucine-rich repeat 277..300 CDD:275380 7/22 (32%)
leucine-rich repeat 301..322 CDD:275380 1/20 (5%)
LRR_8 325..384 CDD:290566 20/58 (34%)
leucine-rich repeat 326..350 CDD:275380 4/23 (17%)
leucine-rich repeat 351..373 CDD:275380 10/21 (48%)
ChadNP_062037.1 LRRNT 22..48 CDD:279764 8/25 (32%)
LRR 1 51..72 6/22 (27%)
leucine-rich repeat 52..75 CDD:275380 7/24 (29%)
LRR_8 74..134 CDD:290566 16/66 (24%)
LRR 2 75..96 4/27 (15%)
leucine-rich repeat 76..99 CDD:275380 4/22 (18%)
LRR_RI <89..281 CDD:238064 70/265 (26%)
LRR 3 99..120 6/20 (30%)
leucine-rich repeat 100..123 CDD:275380 7/22 (32%)
LRR 4 123..144 8/20 (40%)
leucine-rich repeat 124..147 CDD:275380 10/22 (45%)
LRR_8 147..206 CDD:290566 22/107 (21%)
LRR 5 147..168 7/20 (35%)
leucine-rich repeat 148..171 CDD:275380 8/22 (36%)
LRR 6 171..192 10/45 (22%)
leucine-rich repeat 172..195 CDD:275380 11/47 (23%)
LRR_8 195..255 CDD:290566 20/97 (21%)
LRR 7 195..216 7/44 (16%)
leucine-rich repeat 196..219 CDD:275380 10/46 (22%)
LRR 8 219..240 7/20 (35%)
leucine-rich repeat 220..243 CDD:275380 7/36 (19%)
LRR_8 243..300 CDD:290566 22/68 (32%)
LRR 9 244..265 6/31 (19%)
leucine-rich repeat 245..268 CDD:275380 7/33 (21%)
LRR 10 268..289 10/21 (48%)
LRRCT 299..346 CDD:214507 15/53 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 321..358 9/39 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24373
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
33.010

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