Protein Alignment trn and Lrrtm4

DIOPT Version :9

• Sequence 1: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001128215.1
• Gene: Lrrtm4 / 243499
• MGIID: 2389180
• Length: 591
• Species: Mus musculus
• Alignment Length: 660
• Identity: 151/660 - (22%)
• Similarity: 235/660 - (35%)
• Gaps: 209/660 - (31%)

  Fly    30 CPPGCQCDDNTLVVQCGEGQLDVLPIALNPSIQRLVIKSNKIKTIDSSIQFYAELTFLDLSSNHL 94
            ||..|:||..  :|.|.......:|..::...|.|.::.|.|:.:.|:
Mouse    35 CPKNCRCDGK--IVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSN----------------- 80

  Fly    95 MTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRGNQISELHQGTFTPLLKIEEL 159
                  .||...:|..::|:||.|..:....|.|:..:..|.|..|:|:.||..||.|:..:..|
Mouse    81 ------QFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNL 139

  Fly   160 NLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMPSLAELFLGMNTLQSIQADAFQ 224
            :|..|::..|..:.|.||.:|.||:|..|:|.|||..|                         ||
Mouse   140 DLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRV-------------------------FQ 179

  Fly   225 DLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRLEQLSLGQNDFEV 289
            |.:.|..|:|....||::|.::|.||.:|:.|.|..|:..:|......:|..|..:.|..|....
Mouse   180 DCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRS 244

  Fly   290 ISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGALSGLSQLKHV 354
            :|:|.......|..|:::|. .::.:..|.|....||:.|||.|||         |:.:||
Mouse   245 VSQGLTWTWSSLHTLDLSGN-DIQAIEPGTFKCLPNLQKLNLDSNK---------LTNVSQ---- 295

  Fly   355 VLKANALTSLAEGLFPWKDLQTLDLSENPLSCD---CRVM-WLHNLLVAKNASQDDVSELLCEFP 415
                       |.:..|..|.::.||.|...|.   |.:. ||      ||...:..|.::|..|
Mouse   296 -----------ETVNAWISLISITLSGNMWECSRSICPLFYWL------KNFKGNKESTMICAGP 343

  Fly   416 ERLRGESL--------------------RHLN---------------------PAMMGCTHADPR 439
            :.::||.:                    .||.                     ||.:......|.
Mouse   344 KHIQGEKVSDAVETYNICSDVQVVNTERSHLAPQTPQKPPFIPKPTIFKPDAVPATLEAVSPSPG 408

  Fly   440 KQ----------ALIGALLVGSAATITALALVLY-----------------------RCRHKIRE 471
            .|          .....::.||.|...::|::|.                       |.|.|.||
Mouse   409 FQIPGTDHEYEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPASMKQLQQHSLMKRRRKKARE 473

  Fly   472 TIKGGLWGNSALGRKEREYQKTFCDEDYMSRHQHHPCSLGIHSTFPNTYT--------APHHPGA 528
            :.:   ..||.|.....:|:.|          ......:.::.:.|.|||        .|||
Mouse   474 SER---QMNSPLQEYYVDYKPT----------NSETMDISVNGSGPCTYTISGSRECEIPHH--- 522

  Fly   529 THHYGMCPMPVNDLGAIDPQQKFQQLVVPTATMISEKKLNNNKAL----VSQGAIDDSASFVL-- 587
                      |..|    |...:.|.|:....  :.:.|:.|||.    :.|   |||.|..|
Mouse   523 ----------VKPL----PYYSYDQPVIGYCQ--AHQPLHINKAYEAVSIEQ---DDSPSLELGR 568

  Fly   588 -HMKSATMGR 596
             |...||:.|
Mouse   569 DHSFIATIAR 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	5/17 (29%)
		LRR_8	83..142	CDD:290566	12/58 (21%)
		leucine-rich repeat	84..107	CDD:275380	2/22 (9%)
		leucine-rich repeat	108..131	CDD:275380	7/22 (32%)
		LRR_RI	129..421	CDD:238064	80/295 (27%)
		LRR_8	132..190	CDD:290566	21/57 (37%)
		leucine-rich repeat	132..155	CDD:275380	9/22 (41%)
		leucine-rich repeat	156..179	CDD:275380	7/22 (32%)
		leucine-rich repeat	180..204	CDD:275380	10/23 (43%)
		LRR_8	203..263	CDD:290566	16/59 (27%)
		leucine-rich repeat	205..228	CDD:275380	3/22 (14%)
		leucine-rich repeat	229..252	CDD:275380	9/22 (41%)
		LRR_8	252..308	CDD:290566	13/55 (24%)
		leucine-rich repeat	253..276	CDD:275380	6/22 (27%)
		leucine-rich repeat	277..300	CDD:275380	5/22 (23%)
		leucine-rich repeat	301..322	CDD:275380	5/20 (25%)
		LRR_8	325..384	CDD:290566	17/58 (29%)
		leucine-rich repeat	326..350	CDD:275380	8/23 (35%)
		leucine-rich repeat	351..373	CDD:275380	2/21 (10%)
Lrrtm4	NP_001128215.1	leucine-rich repeat	44..62	CDD:275380	3/19 (16%)
		leucine-rich repeat	65..87	CDD:275380	7/44 (16%)
		LRR_8	87..146	CDD:316378	19/58 (33%)
		leucine-rich repeat	88..111	CDD:275380	7/22 (32%)
		leucine-rich repeat	112..135	CDD:275380	9/22 (41%)
		LRR_8	134..194	CDD:316378	23/84 (27%)
		leucine-rich repeat	136..159	CDD:275380	7/22 (32%)
		leucine-rich repeat	160..183	CDD:275380	13/47 (28%)
		leucine-rich repeat	184..207	CDD:275380	9/22 (41%)
		leucine-rich repeat	208..231	CDD:275380	6/22 (27%)
		LRR_8	231..290	CDD:316378	18/68 (26%)
		leucine-rich repeat	232..255	CDD:275380	5/22 (23%)
		leucine-rich repeat	256..279	CDD:275380	5/23 (22%)
		leucine-rich repeat	304..316	CDD:275378	4/11 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24373
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010