DRSC/TRiP Functional Genomics Resources

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Protein Alignment trn and Lrit2

DIOPT Version :9

Sequence 1:NP_001261796.1 Gene:trn / 39491 FlyBaseID:FBgn0010452 Length:751 Species:Drosophila melanogaster
Sequence 2:NP_775594.1 Gene:Lrit2 / 239038 MGIID:2444885 Length:549 Species:Mus musculus


Alignment Length:498 Identity:107/498 - (21%)
Similarity:167/498 - (33%) Gaps:165/498 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   149 TFTPLLKIEELNLGENRIGYLDPKAF-DGLSQLRILYLDDNALTTVPDPVIFQAMPSLAELFLGM 212
            :|...|:...::||:      .|..| :.|.|:||    :|:.........|..|.||..|:|..
Mouse    34 SFGRSLQCMSMSLGK------IPDNFPEELKQVRI----ENSPLFELSQGFFTNMSSLEYLWLNF 88

  Fly   213 NTLQSIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRL 277
            |.:..|...|.:||..|..|.|:|..||::...:|.....||:|||..||:|.:|.:.|..|..|
Mouse    89 NNVTVIHLGALEDLPELRELRLEGNKLRSVPWTAFRATPLLRVLDLKHNRIDSVPELALQFLTNL 153

  Fly   278 EQLSLGQNDFEVISEGAFMGLKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQE 342
            ..|.:..|...|:|:|.|:          |.....||...|.                       
Mouse   154 IYLDISSNRLTVVSKGVFL----------NWPAYQKRQQLGC----------------------- 185

  Fly   343 GALSGLSQLKHVVLKANALTSLAEGLFPWKDLQTLDLSENPLSCDCRVMWLHNLLVAKNASQDDV 407
                |...|.::|                     |.|..||..||||:..|...:  |:.....:
Mouse   186 ----GAEFLSNMV---------------------LSLHNNPWLCDCRLRGLAQFV--KSVGPPFI 223

  Fly   408 ---SELLCEFPERLRGESLRHLNPAM-MGCTHADPRKQALIGALLVGSAATITALALVLYRCRHK 468
               |.|:|:.|....|:.|......: |..|.:.|.....|   .||...|:...|         
Mouse   224 LVNSYLVCQGPVSKAGQLLHETELGVCMKPTISTPSVNVTI---QVGKNVTLQCFA--------- 276

  Fly   469 IRETIKGGLWGNSALGRKEREYQKTFCDEDYMSRHQHHPCSLGIHSTFPNTYTAPHHPGAT-HHY 532
                                                         ...|:...|..:|.:| ..:
Mouse   277 ---------------------------------------------QASPSPTIAWKYPLSTWREF 296

  Fly   533 GMCPMPVNDLGAIDPQQKFQQLVVPTATMISEKKLNNNKALVSQGAIDDSASFV-LHMKSATMGR 596
            .:...|:.: |.|     ..|||:|.|.::.    ..|...::..:|..|:..: |:::.|    
Mouse   297 DVLASPIAE-GII-----LSQLVIPAAQLVD----GGNYTCMAFNSIGRSSLVILLYVQPA---- 347

  Fly   597 DVHQQNPQLNHYTKPQFLSATATVGDSCYSYADVPM----VHG 635
               |..|.|:      |||.::.|.    :|.|:.:    |||
Mouse   348 ---QAMPGLH------FLSTSSEVS----AYVDLRVVKQTVHG 377

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
trnNP_001261796.1 leucine-rich repeat 62..80 CDD:275380
LRR_8 83..142 CDD:290566
leucine-rich repeat 84..107 CDD:275380
leucine-rich repeat 108..131 CDD:275380
LRR_RI 129..421 CDD:238064 68/275 (25%)
LRR_8 132..190 CDD:290566 11/41 (27%)
leucine-rich repeat 132..155 CDD:275380 1/5 (20%)
leucine-rich repeat 156..179 CDD:275380 5/23 (22%)
leucine-rich repeat 180..204 CDD:275380 5/23 (22%)
LRR_8 203..263 CDD:290566 22/59 (37%)
leucine-rich repeat 205..228 CDD:275380 8/22 (36%)
leucine-rich repeat 229..252 CDD:275380 7/22 (32%)
LRR_8 252..308 CDD:290566 18/55 (33%)
leucine-rich repeat 253..276 CDD:275380 11/22 (50%)
leucine-rich repeat 277..300 CDD:275380 7/22 (32%)
leucine-rich repeat 301..322 CDD:275380 4/20 (20%)
LRR_8 325..384 CDD:290566 6/58 (10%)
leucine-rich repeat 326..350 CDD:275380 1/23 (4%)
leucine-rich repeat 351..373 CDD:275380 2/21 (10%)
Lrit2NP_775594.1 LRR_8 56..115 CDD:290566 20/62 (32%)
leucine-rich repeat 57..80 CDD:275378 7/26 (27%)
LRR_4 80..119 CDD:289563 15/38 (39%)
leucine-rich repeat 81..104 CDD:275378 8/22 (36%)
LRR_8 103..163 CDD:290566 21/59 (36%)
leucine-rich repeat 105..128 CDD:275378 7/22 (32%)
LRR_4 129..164 CDD:289563 14/34 (41%)
leucine-rich repeat 129..152 CDD:275378 11/22 (50%)
leucine-rich repeat 153..164 CDD:275378 3/10 (30%)
leucine-rich repeat 193..204 CDD:275378 5/31 (16%)
TPKR_C2 200..243 CDD:301599 13/44 (30%)
I-set 253..344 CDD:254352 23/157 (15%)
Ig 266..345 CDD:299845 20/142 (14%)
fn3 367..441 CDD:278470 4/11 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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